These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 17083961)

  • 1. Synthesis with good enantiomeric excess of both enantiomers of alpha-ketols and acetolactates by two thiamin diphosphate-dependent decarboxylases.
    Baykal A; Chakraborty S; Dodoo A; Jordan F
    Bioorg Chem; 2006 Dec; 34(6):380-93. PubMed ID: 17083961
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Catalytic acid-base groups in yeast pyruvate decarboxylase. 2. Insights into the specific roles of D28 and E477 from the rates and stereospecificity of formation of carboligase side products.
    Sergienko EA; Jordan F
    Biochemistry; 2001 Jun; 40(25):7369-81. PubMed ID: 11412091
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tetrahedral intermediates in thiamin diphosphate-dependent decarboxylations exist as a 1',4'-imino tautomeric form of the coenzyme, unlike the michaelis complex or the free coenzyme.
    Nemeria N; Baykal A; Joseph E; Zhang S; Yan Y; Furey W; Jordan F
    Biochemistry; 2004 Jun; 43(21):6565-75. PubMed ID: 15157089
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glutamate 636 of the Escherichia coli pyruvate dehydrogenase-E1 participates in active center communication and behaves as an engineered acetolactate synthase with unusual stereoselectivity.
    Nemeria N; Tittmann K; Joseph E; Zhou L; Vazquez-Coll MB; Arjunan P; Hübner G; Furey W; Jordan F
    J Biol Chem; 2005 Jun; 280(22):21473-82. PubMed ID: 15802265
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bifunctionality of the thiamin diphosphate cofactor: assignment of tautomeric/ionization states of the 4'-aminopyrimidine ring when various intermediates occupy the active sites during the catalysis of yeast pyruvate decarboxylase.
    Balakrishnan A; Gao Y; Moorjani P; Nemeria NS; Tittmann K; Jordan F
    J Am Chem Soc; 2012 Feb; 134(8):3873-85. PubMed ID: 22300533
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 2-Oxo-3-alkynoic acids, universal mechanism-based inactivators of thiamin diphosphate-dependent decarboxylases: synthesis and evidence for potent inactivation of the pyruvate dehydrogenase multienzyme complex.
    Brown A; Nemeria N; Yi J; Zhang D; Jordan WB; Machado RS; Guest JR; Jordan F
    Biochemistry; 1997 Jul; 36(26):8071-81. PubMed ID: 9201955
    [TBL] [Abstract][Full Text] [Related]  

  • 7. C2-alpha-lactylthiamin diphosphate is an intermediate on the pathway of thiamin diphosphate-dependent pyruvate decarboxylation. Evidence on enzymes and models.
    Zhang S; Liu M; Yan Y; Zhang Z; Jordan F
    J Biol Chem; 2004 Dec; 279(52):54312-8. PubMed ID: 15501823
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Multiple modes of active center communication in thiamin diphosphate-dependent enzymes.
    Jordan F; Nemeria NS; Sergienko E
    Acc Chem Res; 2005 Sep; 38(9):755-63. PubMed ID: 16171318
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutagenesis at asp27 of pyruvate decarboxylase from Zymomonas mobilis. Effect on its ability to form acetoin and acetolactate.
    Wu YG; Chang AK; Nixon PF; Li W; Duggleby RG
    Eur J Biochem; 2000 Nov; 267(21):6493-500. PubMed ID: 11029594
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Spectroscopic evidence for participation of the 1',4'-imino tautomer of thiamin diphosphate in catalysis by yeast pyruvate decarboxylase.
    Jordan F; Zhang Z; Sergienko E
    Bioorg Chem; 2002 Jun; 30(3):188-98. PubMed ID: 12406703
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of thiamin diphosphate-dependent 2-oxo acid decarboxylases by substrate and thiamin diphosphate.Mg(II) - evidence for tertiary and quaternary interactions.
    Jordan F; Nemeria N; Guo F; Baburina I; Gao Y; Kahyaoglu A; Li H; Wang J; Yi J; Guest JR; Furey W
    Biochim Biophys Acta; 1998 Jun; 1385(2):287-306. PubMed ID: 9655921
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Application of alpha-keto acid decarboxylases in biotransformations.
    Iding H; Siegert P; Mesch K; Pohl M
    Biochim Biophys Acta; 1998 Jun; 1385(2):307-22. PubMed ID: 9655924
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation.
    Hohmann S; Meacock PA
    Biochim Biophys Acta; 1998 Jun; 1385(2):201-19. PubMed ID: 9655908
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Intermediates and transition states in thiamin diphosphate-dependent decarboxylases. A kinetic and NMR study on wild-type indolepyruvate decarboxylase and variants using indolepyruvate, benzoylformate, and pyruvate as substrates.
    Schütz A; Golbik R; König S; Hübner G; Tittmann K
    Biochemistry; 2005 Apr; 44(16):6164-79. PubMed ID: 15835904
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Competence of Thiamin Diphosphate-Dependent Enzymes with 2'-Methoxythiamin Diphosphate Derived from Bacimethrin, a Naturally Occurring Thiamin Anti-vitamin.
    Nemeria NS; Shome B; DeColli AA; Heflin K; Begley TP; Meyers CF; Jordan F
    Biochemistry; 2016 Feb; 55(7):1135-48. PubMed ID: 26813608
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Thiamin-dependent enzymes as catalysts in chemoenzymatic syntheses.
    Schörken U; Sprenger GA
    Biochim Biophys Acta; 1998 Jun; 1385(2):229-43. PubMed ID: 9655911
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dual catalytic apparatus of the thiamin diphosphate coenzyme: acid-base via the 1',4'-iminopyrimidine tautomer along with its electrophilic role.
    Jordan F; Nemeria NS; Zhang S; Yan Y; Arjunan P; Furey W
    J Am Chem Soc; 2003 Oct; 125(42):12732-8. PubMed ID: 14558820
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Function of a conserved loop of the beta-domain, not involved in thiamin diphosphate binding, in catalysis and substrate activation in yeast pyruvate decarboxylase.
    Joseph E; Wei W; Tittmann K; Jordan F
    Biochemistry; 2006 Nov; 45(45):13517-27. PubMed ID: 17087505
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Engineering stereoselectivity of ThDP-dependent enzymes.
    Hailes HC; Rother D; Müller M; Westphal R; Ward JM; Pleiss J; Vogel C; Pohl M
    FEBS J; 2013 Dec; 280(24):6374-94. PubMed ID: 24034356
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of substitution of tryptophan 412 in the substrate activation pathway of yeast pyruvate decarboxylase.
    Li H; Jordan F
    Biochemistry; 1999 Aug; 38(31):10004-12. PubMed ID: 10433707
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.