BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

299 related articles for article (PubMed ID: 17084458)

  • 1. On the identity and reactivity patterns of the "second oxidant" of the T252A mutant of cytochrome P450cam in the oxidation of 5-methylenenylcamphor.
    Hirao H; Kumar D; Shaik S
    J Inorg Biochem; 2006 Dec; 100(12):2054-68. PubMed ID: 17084458
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A proton-shuttle mechanism mediated by the porphyrin in benzene hydroxylation by cytochrome p450 enzymes.
    de Visser SP; Shaik S
    J Am Chem Soc; 2003 Jun; 125(24):7413-24. PubMed ID: 12797816
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The influence of substrate on the spectral properties of oxyferrous wild-type and T252A cytochrome P450-CAM.
    Sono M; Perera R; Jin S; Makris TM; Sligar SG; Bryson TA; Dawson JH
    Arch Biochem Biophys; 2005 Apr; 436(1):40-9. PubMed ID: 15752707
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Quantum mechanical/molecular mechanical calculated reactivity networks reveal how cytochrome P450cam and Its T252A mutant select their oxidation pathways.
    Wang B; Li C; Dubey KD; Shaik S
    J Am Chem Soc; 2015 Jun; 137(23):7379-90. PubMed ID: 26011529
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Epoxidation of olefins by hydroperoxo-ferric cytochrome P450.
    Jin S; Makris TM; Bryson TA; Sligar SG; Dawson JH
    J Am Chem Soc; 2003 Mar; 125(12):3406-7. PubMed ID: 12643683
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gauging the relative oxidative powers of compound I, ferric-hydroperoxide, and the ferric-hydrogen peroxide species of cytochrome P450 toward C-H hydroxylation of a radical clock substrate.
    Derat E; Kumar D; Hirao H; Shaik S
    J Am Chem Soc; 2006 Jan; 128(2):473-84. PubMed ID: 16402834
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Is the ruthenium analogue of compound I of cytochrome p450 an efficient oxidant? A theoretical investigation of the methane hydroxylation reaction.
    Sharma PK; De Visser SP; Ogliaro F; Shaik S
    J Am Chem Soc; 2003 Feb; 125(8):2291-300. PubMed ID: 12590559
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Is the bound substrate in nitric oxide synthase protonated or neutral and what is the active oxidant that performs substrate hydroxylation?
    de Visser SP; Tan LS
    J Am Chem Soc; 2008 Oct; 130(39):12961-74. PubMed ID: 18774806
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fundamental differences of substrate hydroxylation by high-valent iron(IV)-oxo models of cytochrome P450.
    Tahsini L; Bagherzadeh M; Nam W; de Visser SP
    Inorg Chem; 2009 Jul; 48(14):6661-9. PubMed ID: 19469505
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Can ferric-superoxide act as a potential oxidant in P450(cam)? QM/MM investigation of hydroxylation, epoxidation, and sulfoxidation.
    Lai W; Shaik S
    J Am Chem Soc; 2011 Apr; 133(14):5444-52. PubMed ID: 21413763
    [TBL] [Abstract][Full Text] [Related]  

  • 11. What factors affect the regioselectivity of oxidation by cytochrome p450? A DFT study of allylic hydroxylation and double bond epoxidation in a model reaction.
    de Visser SP; Ogliaro F; Sharma PK; Shaik S
    J Am Chem Soc; 2002 Oct; 124(39):11809-26. PubMed ID: 12296749
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular recognition in (+)-alpha-pinene oxidation by cytochrome P450cam.
    Bell SG; Chen X; Sowden RJ; Xu F; Williams JN; Wong LL; Rao Z
    J Am Chem Soc; 2003 Jan; 125(3):705-14. PubMed ID: 12526670
    [TBL] [Abstract][Full Text] [Related]  

  • 13. What factors influence the rate constant of substrate epoxidation by compound I of cytochrome P450 and analogous iron(IV)-oxo oxidants?
    Kumar D; Karamzadeh B; Sastry GN; de Visser SP
    J Am Chem Soc; 2010 Jun; 132(22):7656-67. PubMed ID: 20481499
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rapid kinetics investigations of peracid oxidation of ferric cytochrome P450cam: nature and possible function of compound ES.
    Spolitak T; Dawson JH; Ballou DP
    J Inorg Biochem; 2006 Dec; 100(12):2034-44. PubMed ID: 17095096
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Substrate modulation of the properties and reactivity of the oxy-ferrous and hydroperoxo-ferric intermediates of cytochrome P450cam as shown by cryoreduction-EPR/ENDOR spectroscopy.
    Davydov R; Perera R; Jin S; Yang TC; Bryson TA; Sono M; Dawson JH; Hoffman BM
    J Am Chem Soc; 2005 Feb; 127(5):1403-13. PubMed ID: 15686372
    [TBL] [Abstract][Full Text] [Related]  

  • 16. QM/MM study of mechanisms for compound I formation in the catalytic cycle of cytochrome P450cam.
    Zheng J; Wang D; Thiel W; Shaik S
    J Am Chem Soc; 2006 Oct; 128(40):13204-15. PubMed ID: 17017800
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Trends in substrate hydroxylation reactions by heme and nonheme iron(IV)-oxo oxidants give correlations between intrinsic properties of the oxidant with barrier height.
    de Visser SP
    J Am Chem Soc; 2010 Jan; 132(3):1087-97. PubMed ID: 20041691
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Searching for the second oxidant in the catalytic cycle of cytochrome P450: a theoretical investigation of the iron(III)-hydroperoxo species and its epoxidation pathways.
    Ogliaro F; de Visser SP; Cohen S; Sharma PK; Shaik S
    J Am Chem Soc; 2002 Mar; 124(11):2806-17. PubMed ID: 11890833
    [TBL] [Abstract][Full Text] [Related]  

  • 19. What is the active species of cytochrome P450 during camphor hydroxylation? QM/MM studies of different electronic states of compound I and of reduced and oxidized iron-oxo intermediates.
    Altun A; Shaik S; Thiel W
    J Am Chem Soc; 2007 Jul; 129(29):8978-87. PubMed ID: 17595079
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cryoreduction EPR and 13C, 19F ENDOR study of substrate-bound substates and solvent kinetic isotope effects in the catalytic cycle of cytochrome P450cam and its T252A mutant.
    Kim SH; Yang TC; Perera R; Jin S; Bryson TA; Sono M; Davydov R; Dawson JH; Hoffman BM
    Dalton Trans; 2005 Nov; (21):3464-9. PubMed ID: 16234926
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.