BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

334 related articles for article (PubMed ID: 17088896)

  • 21. The molecular chaperone Hsp90 plays a role in the assembly and maintenance of the 26S proteasome.
    Imai J; Maruya M; Yashiroda H; Yahara I; Tanaka K
    EMBO J; 2003 Jul; 22(14):3557-67. PubMed ID: 12853471
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Heat shock protein 90 is important for Sp1 stability during mitosis.
    Wang SA; Chuang JY; Yeh SH; Wang YT; Liu YW; Chang WC; Hung JJ
    J Mol Biol; 2009 Apr; 387(5):1106-19. PubMed ID: 19245816
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The molecular chaperone Hsp90 regulates accumulation of DNA polymerase eta at replication stalling sites in UV-irradiated cells.
    Sekimoto T; Oda T; Pozo FM; Murakumo Y; Masutani C; Hanaoka F; Yamashita T
    Mol Cell; 2010 Jan; 37(1):79-89. PubMed ID: 20129057
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The stabilization mechanism of mutant-type p53 by impaired ubiquitination: the loss of wild-type p53 function and the hsp90 association.
    Nagata Y; Anan T; Yoshida T; Mizukami T; Taya Y; Fujiwara T; Kato H; Saya H; Nakao M
    Oncogene; 1999 Oct; 18(44):6037-49. PubMed ID: 10557093
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Negative feedback loop in T cell activation through IkappaB kinase-induced phosphorylation and degradation of Bcl10.
    Lobry C; Lopez T; Israƫl A; Weil R
    Proc Natl Acad Sci U S A; 2007 Jan; 104(3):908-13. PubMed ID: 17213322
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Delineating role of ubiquitination on nuclear factor-kappa B pathway by a computational modeling approach.
    Lee J; Choi K; Choi C
    Biochem Biophys Res Commun; 2010 Jan; 391(1):33-7. PubMed ID: 19895789
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Alleviating neurodegeneration by an anticancer agent: an Hsp90 inhibitor (17-AAG).
    Waza M; Adachi H; Katsuno M; Minamiyama M; Tanaka F; Sobue G
    Ann N Y Acad Sci; 2006 Nov; 1086():21-34. PubMed ID: 17185503
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Hsp90 inhibitors: small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation.
    Blagg BS; Kerr TD
    Med Res Rev; 2006 May; 26(3):310-38. PubMed ID: 16385472
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Endoplasmic reticulum vacuolization and valosin-containing protein relocalization result from simultaneous hsp90 inhibition by geldanamycin and proteasome inhibition by velcade.
    Mimnaugh EG; Xu W; Vos M; Yuan X; Neckers L
    Mol Cancer Res; 2006 Sep; 4(9):667-81. PubMed ID: 16966435
    [TBL] [Abstract][Full Text] [Related]  

  • 30. 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse.
    Tokui K; Adachi H; Waza M; Katsuno M; Minamiyama M; Doi H; Tanaka K; Hamazaki J; Murata S; Tanaka F; Sobue G
    Hum Mol Genet; 2009 Mar; 18(5):898-910. PubMed ID: 19066230
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Phosphorylation accelerates geldanamycin-induced Akt degradation.
    Su CH; Lan KH; Li CP; Chao Y; Lin HC; Lee SD; Lee WP
    Arch Biochem Biophys; 2013 Aug; 536(1):6-11. PubMed ID: 23668972
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Suppression of the NF-kappaB signalling pathway by ergolide, sesquiterpene lactone, in HeLa cells.
    Chun JK; Seo DW; Ahn SH; Park JH; You JS; Lee CH; Lee JC; Kim YK; Han JW
    J Pharm Pharmacol; 2007 Apr; 59(4):561-6. PubMed ID: 17430640
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The heat-shock protein 90 inhibitor, geldanamycin, induces apoptotic cell death in Epstein-Barr virus-positive NK/T-cell lymphoma by Akt down-regulation.
    Jeon YK; Park CH; Kim KY; Li YC; Kim J; Kim YA; Paik JH; Park BK; Kim CW; Kim YN
    J Pathol; 2007 Oct; 213(2):170-9. PubMed ID: 17768706
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synergistic antipancreatic tumor effect by simultaneously targeting hypoxic cancer cells with HSP90 inhibitor and glycolysis inhibitor.
    Cao X; Bloomston M; Zhang T; Frankel WL; Jia G; Wang B; Hall NC; Koch RM; Cheng H; Knopp MV; Sun D
    Clin Cancer Res; 2008 Mar; 14(6):1831-9. PubMed ID: 18347186
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Inhibition of lysosomal functions reduces proteasomal activity.
    Qiao L; Zhang J
    Neurosci Lett; 2009 May; 456(1):15-9. PubMed ID: 19429125
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Hsp90 inhibitor geldanamycin attenuates the cytotoxicity of sunitinib in cardiomyocytes via inhibition of the autophagy pathway.
    Kimura T; Uesugi M; Takase K; Miyamoto N; Sawada K
    Toxicol Appl Pharmacol; 2017 Aug; 329():282-292. PubMed ID: 28624441
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Two endoplasmic reticulum-associated degradation (ERAD) systems for the novel variant of the mutant dysferlin: ubiquitin/proteasome ERAD(I) and autophagy/lysosome ERAD(II).
    Fujita E; Kouroku Y; Isoai A; Kumagai H; Misutani A; Matsuda C; Hayashi YK; Momoi T
    Hum Mol Genet; 2007 Mar; 16(6):618-29. PubMed ID: 17331981
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The role of ubiquitin in NF-kappaB regulatory pathways.
    Skaug B; Jiang X; Chen ZJ
    Annu Rev Biochem; 2009; 78():769-96. PubMed ID: 19489733
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Molecular characterization of macbecin as an Hsp90 inhibitor.
    Martin CJ; Gaisser S; Challis IR; Carletti I; Wilkinson B; Gregory M; Prodromou C; Roe SM; Pearl LH; Boyd SM; Zhang MQ
    J Med Chem; 2008 May; 51(9):2853-7. PubMed ID: 18357975
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Triad3A regulates ubiquitination and proteasomal degradation of RIP1 following disruption of Hsp90 binding.
    Fearns C; Pan Q; Mathison JC; Chuang TH
    J Biol Chem; 2006 Nov; 281(45):34592-600. PubMed ID: 16968706
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 17.