BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 17089371)

  • 1. Prolonged exposure to homocysteine results in diminished but reversible pancreatic beta-cell responsiveness to insulinotropic agents.
    Patterson S; Scullion SM; McCluskey JT; Flatt PR; McClenaghan NH
    Diabetes Metab Res Rev; 2007 May; 23(4):324-34. PubMed ID: 17089371
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Detrimental actions of metabolic syndrome risk factor, homocysteine, on pancreatic beta-cell glucose metabolism and insulin secretion.
    Patterson S; Flatt PR; Brennan L; Newsholme P; McClenaghan NH
    J Endocrinol; 2006 May; 189(2):301-10. PubMed ID: 16648297
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Homocysteine-induced impairment of insulin secretion from clonal pancreatic BRIN-BD11 beta-cells is not prevented by catalase.
    Patterson S; Flatt PR; McClenaghan NH
    Pancreas; 2007 Jan; 34(1):144-51. PubMed ID: 17198197
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhancement of homocysteine toxicity to insulin-secreting BRIN-BD11 cells in combination with alloxan.
    Scullion SM; Gurgul-Convey E; Elsner M; Lenzen S; Flatt PR; McClenaghan NH
    J Endocrinol; 2012 Aug; 214(2):233-8. PubMed ID: 22582095
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Acute and long-term effects of metformin on the function and insulin secretory responsiveness of clonal β-cells.
    McKiney JM; Irwin N; Flatt PR; Bailey CJ; McClenaghan NH
    Biol Chem; 2010 Dec; 391(12):1451-9. PubMed ID: 20868233
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of the role of N-methyl-D-aspartate (NMDA) receptors in insulin secreting beta-cells.
    Patterson S; Irwin N; Guo-Parke H; Moffett RC; Scullion SM; Flatt PR; McClenaghan NH
    Eur J Pharmacol; 2016 Jan; 771():107-13. PubMed ID: 26688567
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of chronic exposure of clonal β-cells to elevated glucose and free fatty acids on incretin receptor gene expression and secretory responses to GIP and GLP-1.
    Pathak V; Vasu S; Flatt PR; Irwin N
    Diabetes Obes Metab; 2014 Apr; 16(4):357-65. PubMed ID: 24164718
    [TBL] [Abstract][Full Text] [Related]  

  • 8. L-Alanine induces changes in metabolic and signal transduction gene expression in a clonal rat pancreatic beta-cell line and protects from pro-inflammatory cytokine-induced apoptosis.
    Cunningham GA; McClenaghan NH; Flatt PR; Newsholme P
    Clin Sci (Lond); 2005 Nov; 109(5):447-55. PubMed ID: 16045439
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Acute and long-term effects of peroxisome proliferator-activated receptor-γ activation on the function and insulin secretory responsiveness of clonal beta-cells.
    Irwin N; McKinney JM; Bailey CJ; McClenaghan NH; Flatt PR
    Horm Metab Res; 2011 Apr; 43(4):244-9. PubMed ID: 21165811
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Major metabolic homocysteine-derivative, homocysteine thiolactone, exerts changes in pancreatic beta-cell glucose-sensing, cellular signal transduction and integrity.
    Patterson S; Flatt PR; McClenaghan NH
    Arch Biochem Biophys; 2007 May; 461(2):287-93. PubMed ID: 17376398
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Homocysteine and other structurally-diverse amino thiols can alter pancreatic beta cell function without evoking cellular damage.
    Patterson S; Flatt PR; McClenaghan NH
    Biochim Biophys Acta; 2006 Jul; 1760(7):1109-14. PubMed ID: 16632205
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of a novel glucose-responsive insulin-secreting cell line, BRIN-BD11, produced by electrofusion.
    McClenaghan NH; Barnett CR; Ah-Sing E; Abdel-Wahab YH; O'Harte FP; Yoon TW; Swanston-Flatt SK; Flatt PR
    Diabetes; 1996 Aug; 45(8):1132-40. PubMed ID: 8690162
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Costus pictus D. Don leaf extract stimulates GLP-1 secretion from GLUTag L-cells and has cytoprotective effects in BRIN-BD11 β-cells.
    Patibandla C; Khan ZI; MacGregor L; Campbell MJ; Patterson S
    J Ethnopharmacol; 2020 Oct; 260():112970. PubMed ID: 32422353
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Iterative exposure of clonal BRIN-BD11 cells to ninhydrin enables selection of robust toxin-resistant cells but with decreased gene expression of insulin secretory function.
    Liu HK; McCluskey JT; McClenghan NH; Flatt PR
    Pancreas; 2008 Apr; 36(3):294-301. PubMed ID: 18362844
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induced desensitization of the insulinotropic effects of antidiabetic drugs, BTS 67 582 and tolbutamide.
    McClenaghan NH; Ball AJ; Flatt PR
    Br J Pharmacol; 2000 May; 130(2):478-84. PubMed ID: 10807689
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Engineering cultured insulin-secreting pancreatic B-cell lines.
    McClenaghan NH; Flatt PR
    J Mol Med (Berl); 1999 Jan; 77(1):235-43. PubMed ID: 9930971
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evidence for inhibitory autocrine effects of proinsulin C-peptide on pancreatic β-cell function and insulin secretion.
    McKillop AM; Ng MT; Abdel-Wahab YH; Flatt PR
    Diabetes Obes Metab; 2014 Oct; 16(10):937-46. PubMed ID: 24702738
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Detrimental effects of homocysteine on insulin release and apoptosis of pancreatic beta cells].
    Zhang Y; Lu JM; Gu WJ; Yang GQ; Mu YM; Dou JT; Wang BA; Pan CY
    Zhonghua Yi Xue Za Zhi; 2008 Apr; 88(14):990-3. PubMed ID: 18756974
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evaluation of the insulin-releasing and glucose-lowering effects of GPR120 activation in pancreatic β-cells.
    Moran BM; Abdel-Wahab YH; Flatt PR; McKillop AM
    Diabetes Obes Metab; 2014 Nov; 16(11):1128-39. PubMed ID: 24919766
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Prolonged L-alanine exposure induces changes in metabolism, Ca(2+) handling and desensitization of insulin secretion in clonal pancreatic beta-cells.
    McClenaghan NH; Scullion SM; Mion B; Hewage C; Malthouse JP; Flatt PR; Newsholme P; Brennan L
    Clin Sci (Lond); 2009 Feb; 116(4):341-51. PubMed ID: 18702613
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.