165 related articles for article (PubMed ID: 17090533)
1. Increased flexibility enhances misincorporation: temperature effects on nucleotide incorporation opposite a bulky carcinogen-DNA adduct by a Y-family DNA polymerase.
Perlow-Poehnelt RA; Likhterov I; Wang L; Scicchitano DA; Geacintov NE; Broyde S
J Biol Chem; 2007 Jan; 282(2):1397-408. PubMed ID: 17090533
[TBL] [Abstract][Full Text] [Related]
2. Extending the understanding of mutagenicity: structural insights into primer-extension past a benzo[a]pyrene diol epoxide-DNA adduct.
Perlow RA; Broyde S
J Mol Biol; 2003 Apr; 327(4):797-818. PubMed ID: 12654264
[TBL] [Abstract][Full Text] [Related]
3. The spacious active site of a Y-family DNA polymerase facilitates promiscuous nucleotide incorporation opposite a bulky carcinogen-DNA adduct: elucidating the structure-function relationship through experimental and computational approaches.
Perlow-Poehnelt RA; Likhterov I; Scicchitano DA; Geacintov NE; Broyde S
J Biol Chem; 2004 Aug; 279(35):36951-61. PubMed ID: 15210693
[TBL] [Abstract][Full Text] [Related]
4. Evading the proofreading machinery of a replicative DNA polymerase: induction of a mutation by an environmental carcinogen.
Perlow RA; Broyde S
J Mol Biol; 2001 Jun; 309(2):519-36. PubMed ID: 11371169
[TBL] [Abstract][Full Text] [Related]
5. Toward understanding the mutagenicity of an environmental carcinogen: structural insights into nucleotide incorporation preferences.
Perlow RA; Broyde S
J Mol Biol; 2002 Sep; 322(2):291-309. PubMed ID: 12217692
[TBL] [Abstract][Full Text] [Related]
6. Visualizing sequence-governed nucleotide selectivities and mutagenic consequences through a replicative cycle: processing of a bulky carcinogen N2-dG lesion in a Y-family DNA polymerase.
Xu P; Oum L; Lee YC; Geacintov NE; Broyde S
Biochemistry; 2009 Jun; 48(22):4677-90. PubMed ID: 19364137
[TBL] [Abstract][Full Text] [Related]
7. How Y-Family DNA polymerase IV is more accurate than Dpo4 at dCTP insertion opposite an N2-dG adduct of benzo[a]pyrene.
Sholder G; Creech A; Loechler EL
DNA Repair (Amst); 2015 Nov; 35():144-53. PubMed ID: 26523515
[TBL] [Abstract][Full Text] [Related]
8. Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): modeling and dynamics studies.
Zhang L; Rechkoblit O; Wang L; Patel DJ; Shapiro R; Broyde S
Nucleic Acids Res; 2006; 34(11):3326-37. PubMed ID: 16820532
[TBL] [Abstract][Full Text] [Related]
9. A new anti conformation for N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (AAF-dG) allows Watson-Crick pairing in the Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4).
Wang L; Broyde S
Nucleic Acids Res; 2006; 34(3):785-95. PubMed ID: 16452300
[TBL] [Abstract][Full Text] [Related]
10. Effect of N2-guanyl modifications on early steps in catalysis of polymerization by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W.
Zhang H; Guengerich FP
J Mol Biol; 2010 Feb; 395(5):1007-18. PubMed ID: 19969000
[TBL] [Abstract][Full Text] [Related]
11. Solution conformation of the (+)-cis-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove.
Cosman M; Fiala R; Hingerty BE; Amin S; Geacintov NE; Broyde S; Patel DJ
Biochemistry; 1994 Sep; 33(38):11518-27. PubMed ID: 7918365
[TBL] [Abstract][Full Text] [Related]
12. A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment.
Bauer J; Xing G; Yagi H; Sayer JM; Jerina DM; Ling H
Proc Natl Acad Sci U S A; 2007 Sep; 104(38):14905-10. PubMed ID: 17848527
[TBL] [Abstract][Full Text] [Related]
13. DNA adducts from a tumorigenic metabolite of benzo[a]pyrene block human RNA polymerase II elongation in a sequence- and stereochemistry-dependent manner.
Perlow RA; Kolbanovskii A; Hingerty BE; Geacintov NE; Broyde S; Scicchitano DA
J Mol Biol; 2002 Aug; 321(1):29-47. PubMed ID: 12139931
[TBL] [Abstract][Full Text] [Related]
14. Mechanistic investigation of the bypass of a bulky aromatic DNA adduct catalyzed by a Y-family DNA polymerase.
Gadkari VV; Tokarsky EJ; Malik CK; Basu AK; Suo Z
DNA Repair (Amst); 2014 Sep; 21():65-77. PubMed ID: 25048879
[TBL] [Abstract][Full Text] [Related]
15. Versatility of Y-family Sulfolobus solfataricus DNA polymerase Dpo4 in translesion synthesis past bulky N2-alkylguanine adducts.
Zhang H; Eoff RL; Kozekov ID; Rizzo CJ; Egli M; Guengerich FP
J Biol Chem; 2009 Feb; 284(6):3563-76. PubMed ID: 19059910
[TBL] [Abstract][Full Text] [Related]
16. Insights into the mismatch discrimination mechanism of Y-family DNA polymerase Dpo4.
Jung H; Lee S
Biochem J; 2021 May; 478(9):1769-1781. PubMed ID: 33881499
[TBL] [Abstract][Full Text] [Related]
17. Altering DNA polymerase incorporation fidelity by distorting the dNTP binding pocket with a bulky carcinogen-damaged template.
Yan SF; Wu M; Geacintov NE; Broyde S
Biochemistry; 2004 Jun; 43(24):7750-65. PubMed ID: 15196018
[TBL] [Abstract][Full Text] [Related]
18. DNA adduct bypass polymerization by Sulfolobus solfataricus DNA polymerase Dpo4: analysis and crystal structures of multiple base pair substitution and frameshift products with the adduct 1,N2-ethenoguanine.
Zang H; Goodenough AK; Choi JY; Irimia A; Loukachevitch LV; Kozekov ID; Angel KC; Rizzo CJ; Egli M; Guengerich FP
J Biol Chem; 2005 Aug; 280(33):29750-64. PubMed ID: 15965231
[TBL] [Abstract][Full Text] [Related]
19. Mechanistic Basis for the Bypass of a Bulky DNA Adduct Catalyzed by a Y-Family DNA Polymerase.
Vyas R; Efthimiopoulos G; Tokarsky EJ; Malik CK; Basu AK; Suo Z
J Am Chem Soc; 2015 Sep; 137(37):12131-42. PubMed ID: 26327169
[TBL] [Abstract][Full Text] [Related]
20. Mutagenic Replication of N
Gowda ASP; Krzeminski J; Amin S; Suo Z; Spratt TE
Chem Res Toxicol; 2017 May; 30(5):1168-1176. PubMed ID: 28402640
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]