193 related articles for article (PubMed ID: 17092942)
1. Disease-associated mutations at copper ligand histidine residues of superoxide dismutase 1 diminish the binding of copper and compromise dimer stability.
Wang J; Caruano-Yzermans A; Rodriguez A; Scheurmann JP; Slunt HH; Cao X; Gitlin J; Hart PJ; Borchelt DR
J Biol Chem; 2007 Jan; 282(1):345-52. PubMed ID: 17092942
[TBL] [Abstract][Full Text] [Related]
2. Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site.
Wang J; Xu G; Gonzales V; Coonfield M; Fromholt D; Copeland NG; Jenkins NA; Borchelt DR
Neurobiol Dis; 2002 Jul; 10(2):128-38. PubMed ID: 12127151
[TBL] [Abstract][Full Text] [Related]
3. Structural and biophysical properties of the pathogenic SOD1 variant H46R/H48Q.
Winkler DD; Schuermann JP; Cao X; Holloway SP; Borchelt DR; Carroll MC; Proescher JB; Culotta VC; Hart PJ
Biochemistry; 2009 Apr; 48(15):3436-47. PubMed ID: 19227972
[TBL] [Abstract][Full Text] [Related]
4. Heat shock factor 1 over-expression protects against exposure of hydrophobic residues on mutant SOD1 and early mortality in a mouse model of amyotrophic lateral sclerosis.
Lin PY; Simon SM; Koh WK; Folorunso O; Umbaugh CS; Pierce A
Mol Neurodegener; 2013 Nov; 8():43. PubMed ID: 24256636
[TBL] [Abstract][Full Text] [Related]
5. Structural consequences of the familial amyotrophic lateral sclerosis SOD1 mutant His46Arg.
Antonyuk S; Elam JS; Hough MA; Strange RW; Doucette PA; Rodriguez JA; Hayward LJ; Valentine JS; Hart PJ; Hasnain SS
Protein Sci; 2005 May; 14(5):1201-13. PubMed ID: 15840828
[TBL] [Abstract][Full Text] [Related]
6. Copper and zinc metallation status of copper-zinc superoxide dismutase from amyotrophic lateral sclerosis transgenic mice.
Lelie HL; Liba A; Bourassa MW; Chattopadhyay M; Chan PK; Gralla EB; Miller LM; Borchelt DR; Valentine JS; Whitelegge JP
J Biol Chem; 2011 Jan; 286(4):2795-806. PubMed ID: 21068388
[TBL] [Abstract][Full Text] [Related]
7. Common dynamical signatures of familial amyotrophic lateral sclerosis-associated structurally diverse Cu, Zn superoxide dismutase mutants.
Khare SD; Dokholyan NV
Proc Natl Acad Sci U S A; 2006 Feb; 103(9):3147-52. PubMed ID: 16488975
[TBL] [Abstract][Full Text] [Related]
8. Chaperone-facilitated copper binding is a property common to several classes of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants.
Corson LB; Strain JJ; Culotta VC; Cleveland DW
Proc Natl Acad Sci U S A; 1998 May; 95(11):6361-6. PubMed ID: 9600970
[TBL] [Abstract][Full Text] [Related]
9. Copper-binding-site-null SOD1 causes ALS in transgenic mice: aggregates of non-native SOD1 delineate a common feature.
Wang J; Slunt H; Gonzales V; Fromholt D; Coonfield M; Copeland NG; Jenkins NA; Borchelt DR
Hum Mol Genet; 2003 Nov; 12(21):2753-64. PubMed ID: 12966034
[TBL] [Abstract][Full Text] [Related]
10. Decreased metallation and activity in subsets of mutant superoxide dismutases associated with familial amyotrophic lateral sclerosis.
Hayward LJ; Rodriguez JA; Kim JW; Tiwari A; Goto JJ; Cabelli DE; Valentine JS; Brown RH
J Biol Chem; 2002 May; 277(18):15923-31. PubMed ID: 11854284
[TBL] [Abstract][Full Text] [Related]
11. Molecular dynamics using atomic-resolution structure reveal structural fluctuations that may lead to polymerization of human Cu-Zn superoxide dismutase.
Strange RW; Yong CW; Smith W; Hasnain SS
Proc Natl Acad Sci U S A; 2007 Jun; 104(24):10040-4. PubMed ID: 17548825
[TBL] [Abstract][Full Text] [Related]
12. Copper(2+) binding to the surface residue cysteine 111 of His46Arg human copper-zinc superoxide dismutase, a familial amyotrophic lateral sclerosis mutant.
Liu H; Zhu H; Eggers DK; Nersissian AM; Faull KF; Goto JJ; Ai J; Sanders-Loehr J; Gralla EB; Valentine JS
Biochemistry; 2000 Jul; 39(28):8125-32. PubMed ID: 10889018
[TBL] [Abstract][Full Text] [Related]
13. A cysteine residue affects the conformational state and neuronal toxicity of mutant SOD1 in mice: relevance to the pathogenesis of ALS.
Nagano S; Takahashi Y; Yamamoto K; Masutani H; Fujiwara N; Urushitani M; Araki T
Hum Mol Genet; 2015 Jun; 24(12):3427-39. PubMed ID: 25762155
[TBL] [Abstract][Full Text] [Related]
14. Familial amyotrophic lateral sclerosis-associated mutations decrease the thermal stability of distinctly metallated species of human copper/zinc superoxide dismutase.
Rodriguez JA; Valentine JS; Eggers DK; Roe JA; Tiwari A; Brown RH; Hayward LJ
J Biol Chem; 2002 May; 277(18):15932-7. PubMed ID: 11854285
[TBL] [Abstract][Full Text] [Related]
15. FALS mutations in Cu, Zn superoxide dismutase destabilize the dimer and increase dimer dissociation propensity: a large-scale thermodynamic analysis.
Khare SD; Caplow M; Dokholyan NV
Amyloid; 2006 Dec; 13(4):226-35. PubMed ID: 17107883
[TBL] [Abstract][Full Text] [Related]
16. Small-molecule-mediated stabilization of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants against unfolding and aggregation.
Ray SS; Nowak RJ; Brown RH; Lansbury PT
Proc Natl Acad Sci U S A; 2005 Mar; 102(10):3639-44. PubMed ID: 15738401
[TBL] [Abstract][Full Text] [Related]
17. Variation in the biochemical/biophysical properties of mutant superoxide dismutase 1 enzymes and the rate of disease progression in familial amyotrophic lateral sclerosis kindreds.
Ratovitski T; Corson LB; Strain J; Wong P; Cleveland DW; Culotta VC; Borchelt DR
Hum Mol Genet; 1999 Aug; 8(8):1451-60. PubMed ID: 10400992
[TBL] [Abstract][Full Text] [Related]
18. The metal binding properties of the zinc site of yeast copper-zinc superoxide dismutase: implications for amyotrophic lateral sclerosis.
Lyons TJ; Nersissian A; Huang H; Yeom H; Nishida CR; Graden JA; Gralla EB; Valentine JS
J Biol Inorg Chem; 2000 Apr; 5(2):189-203. PubMed ID: 10819464
[TBL] [Abstract][Full Text] [Related]
19. Increased affinity for copper mediated by cysteine 111 in forms of mutant superoxide dismutase 1 linked to amyotrophic lateral sclerosis.
Watanabe S; Nagano S; Duce J; Kiaei M; Li QX; Tucker SM; Tiwari A; Brown RH; Beal MF; Hayward LJ; Culotta VC; Yoshihara S; Sakoda S; Bush AI
Free Radic Biol Med; 2007 May; 42(10):1534-42. PubMed ID: 17448900
[TBL] [Abstract][Full Text] [Related]
20. Palmitoylation of superoxide dismutase 1 (SOD1) is increased for familial amyotrophic lateral sclerosis-linked SOD1 mutants.
Antinone SE; Ghadge GD; Lam TT; Wang L; Roos RP; Green WN
J Biol Chem; 2013 Jul; 288(30):21606-17. PubMed ID: 23760509
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]