BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 17094177)

  • 1. An unconventional IAP-binding motif revealed by target-assisted iterative screening (TAIS) of the BIR3-cIAP1 domain.
    Kurakin A; Bredesen DE
    J Mol Recognit; 2007; 20(1):39-50. PubMed ID: 17094177
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The mechanism of peptide-binding specificity of IAP BIR domains.
    Eckelman BP; Drag M; Snipas SJ; Salvesen GS
    Cell Death Differ; 2008 May; 15(5):920-8. PubMed ID: 18239672
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Determination of the sequence specificity of XIAP BIR domains by screening a combinatorial peptide library.
    Sweeney MC; Wang X; Park J; Liu Y; Pei D
    Biochemistry; 2006 Dec; 45(49):14740-8. PubMed ID: 17144666
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.
    Vucic D; Franklin MC; Wallweber HJ; Das K; Eckelman BP; Shin H; Elliott LO; Kadkhodayan S; Deshayes K; Salvesen GS; Fairbrother WJ
    Biochem J; 2005 Jan; 385(Pt 1):11-20. PubMed ID: 15485396
    [TBL] [Abstract][Full Text] [Related]  

  • 5. E2F1 binds to the peptide-binding groove within the BIR3 domain of cIAP1 and requires cIAP1 for chromatin binding.
    Allègre J; Cartier J; Glorian V; Droin N; Dumetier B; Kayaci C; Berthelet J; Gemble S; Vuillier C; Maillet L; Garrido C; Dubrez L
    PLoS One; 2018; 13(10):e0206253. PubMed ID: 30359437
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.
    Zobel K; Wang L; Varfolomeev E; Franklin MC; Elliott LO; Wallweber HJ; Okawa DC; Flygare JA; Vucic D; Fairbrother WJ; Deshayes K
    ACS Chem Biol; 2006 Sep; 1(8):525-33. PubMed ID: 17168540
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP).
    Franklin MC; Kadkhodayan S; Ackerly H; Alexandru D; Distefano MD; Elliott LO; Flygare JA; Mausisa G; Okawa DC; Ong D; Vucic D; Deshayes K; Fairbrother WJ
    Biochemistry; 2003 Jul; 42(27):8223-31. PubMed ID: 12846571
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural basis for bivalent Smac-mimetics recognition in the IAP protein family.
    Cossu F; Milani M; Mastrangelo E; Vachette P; Servida F; Lecis D; Canevari G; Delia D; Drago C; Rizzo V; Manzoni L; Seneci P; Scolastico C; Bolognesi M
    J Mol Biol; 2009 Sep; 392(3):630-44. PubMed ID: 19393243
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of mammalian mitochondrial proteins that interact with IAPs via N-terminal IAP binding motifs.
    Verhagen AM; Kratina TK; Hawkins CJ; Silke J; Ekert PG; Vaux DL
    Cell Death Differ; 2007 Feb; 14(2):348-57. PubMed ID: 16794601
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recognition of Smac-mimetic compounds by the BIR domain of cIAP1.
    Cossu F; Malvezzi F; Canevari G; Mastrangelo E; Lecis D; Delia D; Seneci P; Scolastico C; Bolognesi M; Milani M
    Protein Sci; 2010 Dec; 19(12):2418-29. PubMed ID: 20954235
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1).
    Blankenship JW; Varfolomeev E; Goncharov T; Fedorova AV; Kirkpatrick DS; Izrael-Tomasevic A; Phu L; Arnott D; Aghajan M; Zobel K; Bazan JF; Fairbrother WJ; Deshayes K; Vucic D
    Biochem J; 2009 Jan; 417(1):149-60. PubMed ID: 18939944
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IAPs: Modular regulators of cell signalling.
    Budhidarmo R; Day CL
    Semin Cell Dev Biol; 2015 Mar; 39():80-90. PubMed ID: 25542341
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Benzazepinones and benzoxazepinones as antagonists of inhibitor of apoptosis proteins (IAPs) selective for the second baculovirus IAP repeat (BIR2) domain.
    Donnell AF; Michoud C; Rupert KC; Han X; Aguilar D; Frank KB; Fretland AJ; Gao L; Goggin B; Hogg JH; Hong K; Janson CA; Kester RF; Kong N; Le K; Li S; Liang W; Lombardo LJ; Lou Y; Lukacs CM; Mischke S; Moliterni JA; Polonskaia A; Schutt AD; Solis DS; Specian A; Taylor RT; Weisel M; Remiszewski SW
    J Med Chem; 2013 Oct; 56(20):7772-87. PubMed ID: 24083782
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo[5.3.0]alkane smac mimetics. Structure, activity, and recognition principles.
    Mastrangelo E; Cossu F; Milani M; Sorrentino G; Lecis D; Delia D; Manzoni L; Drago C; Seneci P; Scolastico C; Rizzo V; Bolognesi M
    J Mol Biol; 2008 Dec; 384(3):673-89. PubMed ID: 18851976
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Optimization of benzodiazepinones as selective inhibitors of the X-linked inhibitor of apoptosis protein (XIAP) second baculovirus IAP repeat (BIR2) domain.
    Kester RF; Donnell AF; Lou Y; Remiszewski SW; Lombardo LJ; Chen S; Le NT; Lo J; Moliterni JA; Han X; Hogg JH; Liang W; Michoud C; Rupert KC; Mischke S; Le K; Weisel M; Janson CA; Lukacs CM; Fretland AJ; Hong K; Polonskaia A; Gao L; Li S; Solis DS; Aguilar D; Tardell C; Dvorozniak M; Tannu S; Lee EC; Schutt AD; Goggin B
    J Med Chem; 2013 Oct; 56(20):7788-803. PubMed ID: 24093940
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination.
    Dueber EC; Schoeffler AJ; Lingel A; Elliott JM; Fedorova AV; Giannetti AM; Zobel K; Maurer B; Varfolomeev E; Wu P; Wallweber HJ; Hymowitz SG; Deshayes K; Vucic D; Fairbrother WJ
    Science; 2011 Oct; 334(6054):376-80. PubMed ID: 22021857
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structures of BIR domains from human NAIP and cIAP2.
    Herman MD; Moche M; Flodin S; Welin M; Trésaugues L; Johansson I; Nilsson M; Nordlund P; Nyman T
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2009 Nov; 65(Pt 11):1091-6. PubMed ID: 19923725
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9.
    Kulathila R; Vash B; Sage D; Cornell-Kennon S; Wright K; Koehn J; Stams T; Clark K; Price A
    Acta Crystallogr D Biol Crystallogr; 2009 Jan; 65(Pt 1):58-66. PubMed ID: 19153467
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Asymmetric recruitment of cIAPs by TRAF2.
    Mace PD; Smits C; Vaux DL; Silke J; Day CL
    J Mol Biol; 2010 Jul; 400(1):8-15. PubMed ID: 20447407
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains.
    Sweeney MC; Wavreille AS; Park J; Butchar JP; Tridandapani S; Pei D
    Biochemistry; 2005 Nov; 44(45):14932-47. PubMed ID: 16274240
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.