BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 17095022)

  • 1. Multiple effects of pentyl-4-yn-VPA enantiomers: from toxicity to short-term memory enhancement.
    Gotfryd K; Owczarek S; Hoffmann K; Klementiev B; Nau H; Berezin V; Bock E; Walmod PS
    Neuropharmacology; 2007 Mar; 52(3):764-78. PubMed ID: 17095022
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prediction of embryotoxic effects of valproic acid-derivatives with molecular in vitro methods.
    Lampen A; Göttlicher M; Nau H
    ALTEX; 2001; 18(2):123-6. PubMed ID: 11378687
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stereoselective dysmorphogenicity of the enantiomers of the valproic acid analogue 2-N-propyl-4-pentynoic acid (4-yn-VPA): cross-species evaluation in whole embryo culture.
    Andrews JE; Ebron-McCoy MT; Bojic U; Nau H; Kavlock RJ
    Teratology; 1997 May; 55(5):314-8. PubMed ID: 9261925
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential enantioselective effects of pentyl-4-yn-valproate on spatial learning in the rat, and neurite outgrowth and cyclin D3 expression in vitro.
    O'Loinsigh ED; Gherardini LM; Gallagher HC; Foley AG; Murphy KJ; Regan CM
    J Neurochem; 2004 Jan; 88(2):370-9. PubMed ID: 14690525
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pentyl-4-yn-valproic acid reverses age-associated memory impairment in the Wistar rat.
    Foley AG; Gallagher HC; Murphy KJ; Regan CM
    Neurobiol Aging; 2004 Apr; 25(4):539-46. PubMed ID: 15013575
    [TBL] [Abstract][Full Text] [Related]  

  • 6. S-2-pentyl-4-pentynoic hydroxamic acid and its metabolite s-2-pentyl-4-pentynoic acid in the NMRI-exencephaly-mouse model: pharmacokinetic profiles, teratogenic effects, and histone deacetylase inhibition abilities of further valproic acid hydroxamates and amides.
    Eikel D; Hoffmann K; Zoll K; Lampen A; Nau H
    Drug Metab Dispos; 2006 Apr; 34(4):612-20. PubMed ID: 16415118
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cell motility is inhibited by the antiepileptic compound, valproic acid and its teratogenic analogues.
    Walmod PS; Foley A; Berezin A; Ellerbeck U; Nau H; Bock E; Berezin V
    Cell Motil Cytoskeleton; 1998; 40(3):220-37. PubMed ID: 9678666
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pentyl-4-yn-valproic acid enhances both spatial and avoidance learning, and attenuates age-related NCAM-mediated neuroplastic decline within the rat medial temporal lobe.
    Murphy KJ; Fox GB; Foley AG; Gallagher HC; O'Connell A; Griffin AM; Nau H; Regan CM
    J Neurochem; 2001 Aug; 78(4):704-14. PubMed ID: 11520891
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New molecular bioassays for the estimation of the teratogenic potency of valproic acid derivatives in vitro: activation of the peroxisomal proliferator-activated receptor (PPARdelta).
    Lampen A; Siehler S; Ellerbeck U; Göttlicher M; Nau H
    Toxicol Appl Pharmacol; 1999 Nov; 160(3):238-49. PubMed ID: 10544058
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The effects of central nervous system-active valproic acid constitutional isomers, cyclopropyl analogs, and amide derivatives on neuronal growth cone behavior.
    Shimshoni JA; Dalton EC; Jenkins A; Eyal S; Ewan K; Williams RS; Pessah N; Yagen B; Harwood AJ; Bialer M
    Mol Pharmacol; 2007 Mar; 71(3):884-92. PubMed ID: 17167030
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of P2, a peptide derived from a homophilic binding site in the neural cell adhesion molecule on learning and memory in rats.
    Rizhova L; Klementiev B; Cambon K; Venero C; Sandi C; Vershinina E; Vaudano E; Berezin V; Bock E
    Neuroscience; 2007 Nov; 149(4):931-42. PubMed ID: 17949921
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prediction of teratogenic potency of valproate analogues using cerebellar aggregation cultures.
    Maar TE; Ellerbeck U; Bock E; Nau H; Schousboe A; Berezin V
    Toxicology; 1997 Jan; 116(1-3):159-68. PubMed ID: 9020517
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Validation of an in vitro teratology system using chiral substances: stereoselective teratogenicity of 4-yn-valproic acid in cultured mouse embryos.
    Andrews JE; Ebron-McCoy M; Bojic U; Nau H; Kavlock RJ
    Toxicol Appl Pharmacol; 1995 Jun; 132(2):310-6. PubMed ID: 7785058
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Valproate decreases inositol biosynthesis.
    Shaltiel G; Shamir A; Shapiro J; Ding D; Dalton E; Bialer M; Harwood AJ; Belmaker RH; Greenberg ML; Agam G
    Biol Psychiatry; 2004 Dec; 56(11):868-74. PubMed ID: 15576064
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pentyl-4-yn-VPA, a histone deacetylase inhibitor, ameliorates deficits in social behavior and cognition in a rodent model of autism spectrum disorders.
    Foley AG; Cassidy AW; Regan CM
    Eur J Pharmacol; 2014 Mar; 727():80-6. PubMed ID: 24486700
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cell proliferation, migration and CAM-dependent neurite outgrowth as developmental in vitro endpoints for screening teratogenic potential: Application to valproic acid and related analogues of varying potency.
    Bacon CL; Berezin V; Bode G; Bock E; Bojic U; Doherty P; Ehlers K; Ellerbeck U; Julien P; Kawa A; Maar TE; Nau H; Pirovano R; Regan CM; Schousboe A; Spezia F; Walsh FS; Williams EJ
    Toxicol In Vitro; 1998 Apr; 12(2):101-9. PubMed ID: 20654391
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug.
    Sobol E; Yagen B; Steve White H; Wilcox KS; Lamb JG; Pappo O; Wlodarczyk BJ; Finnell RH; Bialer M
    Neuropharmacology; 2006 Sep; 51(4):933-46. PubMed ID: 16890251
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The enantiomers of the valproic acid analogue 2-n-propyl-4-pentynoic acid (4-yn-VPA): asymmetric synthesis and highly stereoselective teratogenicity in mice.
    Hauck RS; Nau H
    Pharm Res; 1992 Jul; 9(7):850-5. PubMed ID: 1437995
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid.
    Shimshoni JA; Bialer M; Wlodarczyk B; Finnell RH; Yagen B
    J Med Chem; 2007 Dec; 50(25):6419-27. PubMed ID: 17994680
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes.
    Chen PS; Peng GS; Li G; Yang S; Wu X; Wang CC; Wilson B; Lu RB; Gean PW; Chuang DM; Hong JS
    Mol Psychiatry; 2006 Dec; 11(12):1116-25. PubMed ID: 16969367
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.