152 related articles for article (PubMed ID: 17095214)
1. Development of potent, orally active 1-substituted-3,4-dihydro-2-quinolone glycogen phosphorylase inhibitors.
Birch AM; Kenny PW; Oikonomakos NG; Otterbein L; Schofield P; Whittamore PR; Whalley DP
Bioorg Med Chem Lett; 2007 Jan; 17(2):394-9. PubMed ID: 17095214
[TBL] [Abstract][Full Text] [Related]
2. Novel 3,4-dihydroquinolin-2(1H)-one inhibitors of human glycogen phosphorylase a.
Rosauer KG; Ogawa AK; Willoughby CA; Ellsworth KP; Geissler WM; Myers RW; Deng Q; Chapman KT; Harris G; Moller DE
Bioorg Med Chem Lett; 2003 Dec; 13(24):4385-8. PubMed ID: 14643331
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and glycogen phosphorylase inhibitor activity of functionalized 1,4-benzodioxanes.
Czakó Z; Docsa T; Gergely P; Juhász L; Antus S
Pharmazie; 2010 Apr; 65(4):235-8. PubMed ID: 20432616
[TBL] [Abstract][Full Text] [Related]
4. 5-Chloroindoloyl glycine amide inhibitors of glycogen phosphorylase: synthesis, in vitro, in vivo, and X-ray crystallographic characterization.
Wright SW; Rath VL; Genereux PE; Hageman DL; Levy CB; McClure LD; McCoid SC; McPherson RK; Schelhorn TM; Wilder DE; Zavadoski WJ; Gibbs EM; Treadway JL
Bioorg Med Chem Lett; 2005 Jan; 15(2):459-65. PubMed ID: 15603973
[TBL] [Abstract][Full Text] [Related]
5. A multidisciplinary study of 3-(β-d-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and kinetics reveal new potent inhibitors.
Kun S; Begum J; Kyriakis E; Stamati ECV; Barkas TA; Szennyes E; Bokor É; Szabó KE; Stravodimos GA; Sipos Á; Docsa T; Gergely P; Moffatt C; Patraskaki MS; Kokolaki MC; Gkerdi A; Skamnaki VT; Leonidas DD; Somsák L; Hayes JM
Eur J Med Chem; 2018 Mar; 147():266-278. PubMed ID: 29453094
[TBL] [Abstract][Full Text] [Related]
6. Identification, synthesis, and characterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site.
Kristiansen M; Andersen B; Iversen LF; Westergaard N
J Med Chem; 2004 Jul; 47(14):3537-45. PubMed ID: 15214781
[TBL] [Abstract][Full Text] [Related]
7. Novel thienopyrrole glycogen phosphorylase inhibitors: synthesis, in vitro SAR and crystallographic studies.
Whittamore PR; Addie MS; Bennett SN; Birch AM; Butters M; Godfrey L; Kenny PW; Morley AD; Murray PM; Oikonomakos NG; Otterbein LR; Pannifer AD; Parker JS; Readman K; Siedlecki PS; Schofield P; Stocker A; Taylor MJ; Townsend LA; Whalley DP; Whitehouse J
Bioorg Med Chem Lett; 2006 Nov; 16(21):5567-71. PubMed ID: 16945526
[TBL] [Abstract][Full Text] [Related]
8. Discovering benzamide derivatives as glycogen phosphorylase inhibitors and their binding site at the enzyme.
Chen L; Li H; Liu J; Zhang L; Liu H; Jiang H
Bioorg Med Chem; 2007 Nov; 15(21):6763-74. PubMed ID: 17719791
[TBL] [Abstract][Full Text] [Related]
9. Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy.
Thomson SA; Banker P; Bickett DM; Boucheron JA; Carter HL; Clancy DC; Cooper JP; Dickerson SH; Garrido DM; Nolte RT; Peat AJ; Sheckler LR; Sparks SM; Tavares FX; Wang L; Wang TY; Weiel JE
Bioorg Med Chem Lett; 2009 Feb; 19(4):1177-82. PubMed ID: 19138846
[TBL] [Abstract][Full Text] [Related]
10. Advances in glycogen phosphorylase inhibitor design.
Oikonomakos NG; Somsák L
Curr Opin Investig Drugs; 2008 Apr; 9(4):379-95. PubMed ID: 18393105
[TBL] [Abstract][Full Text] [Related]
11. Synthesis, in vitro ADME profiling and in vivo pharmacological evaluation of novel glycogen phosphorylase inhibitors.
Miao GX; Wang YD; Yan ZW; Zhang LY
Bioorg Med Chem Lett; 2020 Jul; 30(14):127117. PubMed ID: 32527535
[TBL] [Abstract][Full Text] [Related]
12. Synthesis, screening and docking of small heterocycles as glycogen phosphorylase inhibitors.
Schweiker SS; Loughlin WA; Lohning AS; Petersson MJ; Jenkins ID
Eur J Med Chem; 2014 Sep; 84():584-94. PubMed ID: 25062009
[TBL] [Abstract][Full Text] [Related]
13. Probing the β-pocket of the active site of human liver glycogen phosphorylase with 3-(C-β-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors.
Kyriakis E; Solovou TGA; Kun S; Czifrák K; Szőcs B; Juhász L; Bokor É; Stravodimos GA; Kantsadi AL; Chatzileontiadou DSM; Skamnaki VT; Somsák L; Leonidas DD
Bioorg Chem; 2018 Apr; 77():485-493. PubMed ID: 29454281
[TBL] [Abstract][Full Text] [Related]
14. A new class of glycogen phosphorylase inhibitors.
Lu Z; Bohn J; Bergeron R; Deng Q; Ellsworth KP; Geissler WM; Harris G; McCann PE; McKeever B; Myers RW; Saperstein R; Willoughby CA; Yao J; Chapman K
Bioorg Med Chem Lett; 2003 Nov; 13(22):4125-8. PubMed ID: 14592521
[TBL] [Abstract][Full Text] [Related]
15. New inhibitors of glycogen phosphorylase as potential antidiabetic agents.
Somsák L; Czifrák K; Tóth M; Bokor E; Chrysina ED; Alexacou KM; Hayes JM; Tiraidis C; Lazoura E; Leonidas DD; Zographos SE; Oikonomakos NG
Curr Med Chem; 2008; 15(28):2933-83. PubMed ID: 19075645
[TBL] [Abstract][Full Text] [Related]
16. New synthesis of 3-(β-D-glucopyranosyl)-5-substituted-1,2,4-triazoles, nanomolar inhibitors of glycogen phosphorylase.
Kun S; Bokor É; Varga G; Szőcs B; Páhi A; Czifrák K; Tóth M; Juhász L; Docsa T; Gergely P; Somsák L
Eur J Med Chem; 2014 Apr; 76():567-79. PubMed ID: 24608000
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of asiatic acid derivatives as inhibitors of glycogen phosphorylases.
Zhang L; Chen J; Gong Y; Liu J; Zhang L; Hua W; Sun H
Chem Biodivers; 2009 Jun; 6(6):864-74. PubMed ID: 19551727
[TBL] [Abstract][Full Text] [Related]
18. Natural flavonoids as antidiabetic agents. The binding of gallic and ellagic acids to glycogen phosphorylase b.
Kyriakis E; Stravodimos GA; Kantsadi AL; Chatzileontiadou DS; Skamnaki VT; Leonidas DD
FEBS Lett; 2015 Jul; 589(15):1787-94. PubMed ID: 25980608
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological evaluation of ambradiolic acid as an inhibitor of glycogen phosphorylase.
Liu J; Zhang H; Zhu P; Wu X; Yao H; Ye W; Jiang J; Xu J
Fitoterapia; 2015 Jan; 100():50-5. PubMed ID: 25447165
[TBL] [Abstract][Full Text] [Related]
20. Sensitivity of glycogen phosphorylase isoforms to indole site inhibitors is markedly dependent on the activation state of the enzyme.
Freeman S; Bartlett JB; Convey G; Hardern I; Teague JL; Loxham SJ; Allen JM; Poucher SM; Charles AD
Br J Pharmacol; 2006 Nov; 149(6):775-85. PubMed ID: 17016495
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
