BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 17107284)

  • 21. Nelarabine in the treatment of pediatric and adult patients with T-cell acute lymphoblastic leukemia and lymphoma.
    Kadia TM; Gandhi V
    Expert Rev Hematol; 2017 Jan; 10(1):1-8. PubMed ID: 27869523
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Potent orally bioavailable purine nucleoside phosphorylase inhibitor BCX-4208 induces apoptosis in B- and T-lymphocytes--a novel treatment approach for autoimmune diseases, organ transplantation and hematologic malignancies.
    Bantia S; Parker C; Upshaw R; Cunningham A; Kotian P; Kilpatrick JM; Morris P; Chand P; Babu YS
    Int Immunopharmacol; 2010 Jul; 10(7):784-90. PubMed ID: 20399911
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A purine nucleoside phosphorylase (PNP) inhibitor induces apoptosis via caspase-3-like protease activity in MOLT-4 T cells.
    Posmantur R; Wang KK; Nath R; Gilbertsen RB
    Immunopharmacology; 1997 Oct; 37(2-3):231-44. PubMed ID: 9403342
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Determinants of sensitivity of human T-cell leukemia CCRF-CEM cells to immucillin-H.
    Huang M; Wang Y; Gu J; Yang J; Noel K; Mitchell BS; Schramm VL; Graves LM
    Leuk Res; 2008 Aug; 32(8):1268-78. PubMed ID: 18279955
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Mechanisms of 2'-deoxyguanosine toxicity in mouse T-lymphoma cells with purine nucleoside phosphorylase deficiency and resistance to inhibition of ribonucleotide reductase by dGTP.
    Duan DS; Nagashima T; Hoshino T; Waldman F; Pawlak K; Sadee W
    Biochem J; 1990 Jun; 268(3):725-31. PubMed ID: 2114100
    [TBL] [Abstract][Full Text] [Related]  

  • 26. One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase.
    Miles RW; Tyler PC; Furneaux RH; Bagdassarian CK; Schramm VL
    Biochemistry; 1998 Jun; 37(24):8615-21. PubMed ID: 9628722
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Nelarabine (Arranon) for T-cell acute lymphoblastic leukemia.
    Med Lett Drugs Ther; 2006 Feb; 48(1228):14-5. PubMed ID: 16467734
    [No Abstract]   [Full Text] [Related]  

  • 28. Effect of 9-benzyl-9-deazaguanine, a potent inhibitor of purine nucleoside phosphorylase, on the cytotoxicity and metabolism of 6-thio-2'-deoxyguanosine.
    Parker WB; Allan PW; Niwas S; Montgomery JA; Bennett LL
    Cancer Res; 1994 Apr; 54(7):1742-5. PubMed ID: 8137289
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Structure of human PNP complexed with ligands.
    Canduri F; Silva RG; dos Santos DM; Palma MS; Basso LA; Santos DS; de Azevedo WF
    Acta Crystallogr D Biol Crystallogr; 2005 Jul; 61(Pt 7):856-62. PubMed ID: 15983407
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Mechanisms of deoxyguanosine lymphotoxicity. Human thymocytes, but not peripheral blood lymphocytes accumulate deoxy-GTP in conditions simulating purine nucleoside phosphorylase deficiency.
    Fairbanks LD; Taddeo A; Duley JA; Simmonds HA
    J Immunol; 1990 Jan; 144(2):485-91. PubMed ID: 2104895
    [TBL] [Abstract][Full Text] [Related]  

  • 31. In vitro efficacy of forodesine and nelarabine (ara-G) in pediatric leukemia.
    Homminga I; Zwaan CM; Manz CY; Parker C; Bantia S; Smits WK; Higginbotham F; Pieters R; Meijerink JP
    Blood; 2011 Aug; 118(8):2184-90. PubMed ID: 21730354
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Correction of purine nucleoside phosphorylase deficiency by retroviral-mediated gene transfer in mouse S49 T cell lymphoma: a model for gene therapy of T cell immunodeficiency.
    Foresman MD; Nelson DM; McIvor RS
    Hum Gene Ther; 1992 Dec; 3(6):625-31. PubMed ID: 1482702
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Structural basis for inhibition of human PNP by immucillin-H.
    Filgueira de Azevedo W; Canduri F; Marangoni dos Santos D; Pereira JH; Dias MV; Silva RG; Mendes MA; Basso LA; Palma MS; Santos DS
    Biochem Biophys Res Commun; 2003 Oct; 309(4):917-22. PubMed ID: 13679061
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Different pathways for deoxyguanosine toxicity in T-lymphocytes of various developmental stages.
    Scharenberg JG; Rijkers GT; Spaapen LJ; Toebes EA; Rijksen G; Duran M; Staal GE; Zegers BJ
    Int J Immunopharmacol; 1988; 10(6):675-86. PubMed ID: 2974022
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Diagnosis of immunodeficiency caused by a purine nucleoside phosphorylase defect by using tandem mass spectrometry on dried blood spots.
    la Marca G; Canessa C; Giocaliere E; Romano F; Malvagia S; Funghini S; Moriondo M; Valleriani C; Lippi F; Ombrone D; Della Bona ML; Speckmann C; Borte S; Brodszki N; Gennery AR; Weinacht K; Celmeli F; Pagel J; de Martino M; Guerrini R; Wittkowski H; Santisteban I; Bali P; Ikinciogullari A; Hershfield M; Notarangelo LD; Resti M; Azzari C
    J Allergy Clin Immunol; 2014 Jul; 134(1):155-9. PubMed ID: 24767876
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Novel agents in development for peripheral T-cell lymphoma.
    O'Connor OA
    Semin Hematol; 2010 Apr; 47 Suppl 1():S11-4. PubMed ID: 20359580
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synthesis of analogs of forodesine HCl, a human purine nucleoside phosphorylase inhibitor-Part II.
    Kamath VP; Xue J; Juarez-Brambila JJ
    Bioorg Med Chem Lett; 2009 May; 19(10):2627-9. PubMed ID: 19386496
    [TBL] [Abstract][Full Text] [Related]  

  • 38. [Tight binding transition state analogues of purine nucleoside phosphorylase--meaning, design and properties].
    Lewandowicz A
    Postepy Biochem; 2004; 50(3):218-27. PubMed ID: 15822751
    [No Abstract]   [Full Text] [Related]  

  • 39. Synthesis of analogs of forodesine HCl, a human purine nucleoside phosphorylase inhibitor-Part I.
    Kamath VP; Xue J; Juarez-Brambila JJ; Morris CB; Ganorkar R; Morris PE
    Bioorg Med Chem Lett; 2009 May; 19(10):2624-6. PubMed ID: 19386498
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Phase 2 and pharmacodynamic study of oral forodesine in patients with advanced, fludarabine-treated chronic lymphocytic leukemia.
    Balakrishnan K; Verma D; O'Brien S; Kilpatrick JM; Chen Y; Tyler BF; Bickel S; Bantia S; Keating MJ; Kantarjian H; Gandhi V; Ravandi F
    Blood; 2010 Aug; 116(6):886-92. PubMed ID: 20427701
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.