BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

506 related articles for article (PubMed ID: 17110449)

  • 1. Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation.
    Sethi G; Ahn KS; Pandey MK; Aggarwal BB
    Blood; 2007 Apr; 109(7):2727-35. PubMed ID: 17110449
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion.
    Takada Y; Kobayashi Y; Aggarwal BB
    J Biol Chem; 2005 Apr; 280(17):17203-12. PubMed ID: 15710601
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalpha kinase activation.
    Sung B; Pandey MK; Aggarwal BB
    Mol Pharmacol; 2007 Jun; 71(6):1703-14. PubMed ID: 17387141
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis.
    Sethi G; Ahn KS; Sung B; Aggarwal BB
    Mol Cancer Ther; 2008 Jun; 7(6):1604-14. PubMed ID: 18566231
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products.
    Ichikawa H; Takada Y; Murakami A; Aggarwal BB
    J Immunol; 2005 Jun; 174(11):7383-92. PubMed ID: 15905586
    [TBL] [Abstract][Full Text] [Related]  

  • 6. N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products.
    Shishodia S; Gutierrez AM; Lotan R; Aggarwal BB
    Cancer Res; 2005 Oct; 65(20):9555-65. PubMed ID: 16230421
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Salinosporamide A (NPI-0052) potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through down-modulation of NF-kappaB regulated gene products.
    Ahn KS; Sethi G; Chao TH; Neuteboom ST; Chaturvedi MM; Palladino MA; Younes A; Aggarwal BB
    Blood; 2007 Oct; 110(7):2286-95. PubMed ID: 17609425
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway.
    Pandey MK; Sung B; Ahn KS; Kunnumakkara AB; Chaturvedi MM; Aggarwal BB
    Blood; 2007 Nov; 110(10):3517-25. PubMed ID: 17673602
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells.
    Shishodia S; Sethi G; Konopleva M; Andreeff M; Aggarwal BB
    Clin Cancer Res; 2006 Mar; 12(6):1828-38. PubMed ID: 16551868
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells.
    Yadav VR; Prasad S; Gupta SC; Sung B; Phatak SS; Zhang S; Aggarwal BB
    J Biol Chem; 2012 Jan; 287(1):245-256. PubMed ID: 22065587
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis.
    Kunnumakkara AB; Ichikawa H; Anand P; Mohankumar CJ; Hema PS; Nair MS; Aggarwal BB
    Mol Cancer Ther; 2008 Oct; 7(10):3306-17. PubMed ID: 18852134
    [TBL] [Abstract][Full Text] [Related]  

  • 12. β-Caryophyllene oxide potentiates TNFα-induced apoptosis and inhibits invasion through down-modulation of NF-κB-regulated gene products.
    Kim C; Cho SK; Kim KD; Nam D; Chung WS; Jang HJ; Lee SG; Shim BS; Sethi G; Ahn KS
    Apoptosis; 2014 Apr; 19(4):708-18. PubMed ID: 24370994
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agents.
    Sandur SK; Ichikawa H; Sethi G; Ahn KS; Aggarwal BB
    J Biol Chem; 2006 Jun; 281(25):17023-17033. PubMed ID: 16624823
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Indole-3-carbinol suppresses NF-kappaB and IkappaBalpha kinase activation, causing inhibition of expression of NF-kappaB-regulated antiapoptotic and metastatic gene products and enhancement of apoptosis in myeloid and leukemia cells.
    Takada Y; Andreeff M; Aggarwal BB
    Blood; 2005 Jul; 106(2):641-9. PubMed ID: 15811958
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Suberoylanilide hydroxamic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing nuclear factor-kappaB activation.
    Takada Y; Gillenwater A; Ichikawa H; Aggarwal BB
    J Biol Chem; 2006 Mar; 281(9):5612-22. PubMed ID: 16377638
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation.
    Aggarwal S; Ichikawa H; Takada Y; Sandur SK; Shishodia S; Aggarwal BB
    Mol Pharmacol; 2006 Jan; 69(1):195-206. PubMed ID: 16219905
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protein farnesyltransferase inhibitor (SCH 66336) abolishes NF-kappaB activation induced by various carcinogens and inflammatory stimuli leading to suppression of NF-kappaB-regulated gene expression and up-regulation of apoptosis.
    Takada Y; Khuri FR; Aggarwal BB
    J Biol Chem; 2004 Jun; 279(25):26287-99. PubMed ID: 15090542
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kappaB activation pathway.
    Ahn KS; Sethi G; Shishodia S; Sung B; Arbiser JL; Aggarwal BB
    Mol Cancer Res; 2006 Sep; 4(9):621-33. PubMed ID: 16966432
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis.
    Pandey MK; Sung B; Kunnumakkara AB; Sethi G; Chaturvedi MM; Aggarwal BB
    Cancer Res; 2008 Jul; 68(13):5370-9. PubMed ID: 18593939
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Zerumbone abolishes NF-kappaB and IkappaBalpha kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion.
    Takada Y; Murakami A; Aggarwal BB
    Oncogene; 2005 Oct; 24(46):6957-69. PubMed ID: 16007145
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.