BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

381 related articles for article (PubMed ID: 17110594)

  • 1. Hypoxia-induced endothelial proliferation requires both mTORC1 and mTORC2.
    Li W; Petrimpol M; Molle KD; Hall MN; Battegay EJ; Humar R
    Circ Res; 2007 Jan; 100(1):79-87. PubMed ID: 17110594
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility.
    Gulati N; Karsy M; Albert L; Murali R; Jhanwar-Uniyal M
    Int J Oncol; 2009 Oct; 35(4):731-40. PubMed ID: 19724909
    [TBL] [Abstract][Full Text] [Related]  

  • 3. mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
    Julien LA; Carriere A; Moreau J; Roux PP
    Mol Cell Biol; 2010 Feb; 30(4):908-21. PubMed ID: 19995915
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways.
    Wang S; Amato KR; Song W; Youngblood V; Lee K; Boothby M; Brantley-Sieders DM; Chen J
    Mol Cell Biol; 2015 Apr; 35(7):1299-313. PubMed ID: 25582201
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
    Woo SY; Kim DH; Jun CB; Kim YM; Haar EV; Lee SI; Hegg JW; Bandhakavi S; Griffin TJ; Kim DH
    J Biol Chem; 2007 Aug; 282(35):25604-12. PubMed ID: 17599906
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.
    Guertin DA; Stevens DM; Thoreen CC; Burds AA; Kalaany NY; Moffat J; Brown M; Fitzgerald KJ; Sabatini DM
    Dev Cell; 2006 Dec; 11(6):859-71. PubMed ID: 17141160
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rapamycin regulates the phosphorylation of rictor.
    Akcakanat A; Singh G; Hung MC; Meric-Bernstam F
    Biochem Biophys Res Commun; 2007 Oct; 362(2):330-3. PubMed ID: 17707343
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CD40-induced signaling in human endothelial cells results in mTORC2- and Akt-dependent expression of vascular endothelial growth factor in vitro and in vivo.
    Dormond O; Contreras AG; Meijer E; Datta D; Flynn E; Pal S; Briscoe DM
    J Immunol; 2008 Dec; 181(11):8088-95. PubMed ID: 19018001
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.
    Jacinto E; Facchinetti V; Liu D; Soto N; Wei S; Jung SY; Huang Q; Qin J; Su B
    Cell; 2006 Oct; 127(1):125-37. PubMed ID: 16962653
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.
    Feldman ME; Apsel B; Uotila A; Loewith R; Knight ZA; Ruggero D; Shokat KM
    PLoS Biol; 2009 Feb; 7(2):e38. PubMed ID: 19209957
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition.
    Han EK; Leverson JD; McGonigal T; Shah OJ; Woods KW; Hunter T; Giranda VL; Luo Y
    Oncogene; 2007 Aug; 26(38):5655-61. PubMed ID: 17334390
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pravastatin induces rat aortic endothelial cell proliferation and migration via activation of PI3K/Akt/mTOR/p70 S6 kinase signaling.
    Nakao T; Shiota M; Tatemoto Y; Izumi Y; Iwao H
    J Pharmacol Sci; 2007 Dec; 105(4):334-41. PubMed ID: 18057776
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin.
    Toschi A; Lee E; Xu L; Garcia A; Gadir N; Foster DA
    Mol Cell Biol; 2009 Mar; 29(6):1411-20. PubMed ID: 19114562
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of phosphatidylinositol 3-kinase, Akt, and mammalian target of rapamycin is necessary for hypoxia-induced pulmonary artery adventitial fibroblast proliferation.
    Gerasimovskaya EV; Tucker DA; Stenmark KR
    J Appl Physiol (1985); 2005 Feb; 98(2):722-31. PubMed ID: 15501927
    [TBL] [Abstract][Full Text] [Related]  

  • 15. mTOR in renal cell cancer: modulator of tumor biology and therapeutic target.
    Wysocki PJ
    Expert Rev Mol Diagn; 2009 Apr; 9(3):231-41. PubMed ID: 19379082
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of 14-3-3 binding to Rictor of mTORC2 for Akt phosphorylation at Ser473 is regulated by selenoprotein W.
    Jeon YH; Park YH; Kwon JH; Lee JH; Kim IY
    Biochim Biophys Acta; 2013 Oct; 1833(10):2135-42. PubMed ID: 23680186
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RAD 001 (everolimus) prevents mTOR and Akt late re-activation in response to imatinib in chronic myeloid leukemia.
    Mancini M; Petta S; Martinelli G; Barbieri E; Santucci MA
    J Cell Biochem; 2010 Feb; 109(2):320-8. PubMed ID: 20014066
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential dependence of hypoxia-inducible factors 1 alpha and 2 alpha on mTORC1 and mTORC2.
    Toschi A; Lee E; Gadir N; Ohh M; Foster DA
    J Biol Chem; 2008 Dec; 283(50):34495-9. PubMed ID: 18945681
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling.
    Humar R; Kiefer FN; Berns H; Resink TJ; Battegay EJ
    FASEB J; 2002 Jun; 16(8):771-80. PubMed ID: 12039858
    [TBL] [Abstract][Full Text] [Related]  

  • 20. mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).
    García-Martínez JM; Alessi DR
    Biochem J; 2008 Dec; 416(3):375-85. PubMed ID: 18925875
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.