BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 17112240)

  • 1. Chalcone inhibition of anthracycline secondary alcohol metabolite formation in rabbit and human heart cytosol.
    Silvestrini A; Meucci E; Vitali A; Giardina B; Mordente A
    Chem Res Toxicol; 2006 Nov; 19(11):1518-24. PubMed ID: 17112240
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Anthracycline secondary alcohol metabolite formation in human or rabbit heart: biochemical aspects and pharmacologic implications.
    Mordente A; Minotti G; Martorana GE; Silvestrini A; Giardina B; Meucci E
    Biochem Pharmacol; 2003 Sep; 66(6):989-98. PubMed ID: 12963485
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human heart cytosolic reductases and anthracycline cardiotoxicity.
    Mordente A; Meucci E; Martorana GE; Giardina B; Minotti G
    IUBMB Life; 2001 Jul; 52(1-2):83-8. PubMed ID: 11795600
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Secondary alcohol metabolites mediate iron delocalization in cytosolic fractions of myocardial biopsies exposed to anticancer anthracyclines. Novel linkage between anthracycline metabolism and iron-induced cardiotoxicity.
    Minotti G; Cavaliere AF; Mordente A; Rossi M; Schiavello R; Zamparelli R; Possati G
    J Clin Invest; 1995 Apr; 95(4):1595-605. PubMed ID: 7706466
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of Anthracycline Alcohol Metabolite Formation in Human Heart Cytosol: A Potential Role for Several Promising Drugs.
    Mordente A; Silvestrini A; Martorana GE; Tavian D; Meucci E
    Drug Metab Dispos; 2015 Nov; 43(11):1691-701. PubMed ID: 26265744
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Studies of structure-activity relationship on plant polyphenol-induced suppression of human liver cancer cells.
    Loa J; Chow P; Zhang K
    Cancer Chemother Pharmacol; 2009 May; 63(6):1007-16. PubMed ID: 18766342
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chronic cardiotoxicity of anticancer anthracyclines in the rat: role of secondary metabolites and reduced toxicity by a novel anthracycline with impaired metabolite formation and reactivity.
    Sacco G; Giampietro R; Salvatorelli E; Menna P; Bertani N; Graiani G; Animati F; Goso C; Maggi CA; Manzini S; Minotti G
    Br J Pharmacol; 2003 Jun; 139(3):641-51. PubMed ID: 12788824
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Impairment of myocardial contractility by anticancer anthracyclines: role of secondary alcohol metabolites and evidence of reduced toxicity by a novel disaccharide analogue.
    Minotti G; Parlani M; Salvatorelli E; Menna P; Cipollone A; Animati F; Maggi CA; Manzini S
    Br J Pharmacol; 2001 Nov; 134(6):1271-8. PubMed ID: 11704647
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Doxorubicin metabolism and toxicity in human myocardium: role of cytoplasmic deglycosidation and carbonyl reduction.
    Licata S; Saponiero A; Mordente A; Minotti G
    Chem Res Toxicol; 2000 May; 13(5):414-20. PubMed ID: 10813659
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Doxorubicin irreversibly inactivates iron regulatory proteins 1 and 2 in cardiomyocytes: evidence for distinct metabolic pathways and implications for iron-mediated cardiotoxicity of antitumor therapy.
    Minotti G; Ronchi R; Salvatorelli E; Menna P; Cairo G
    Cancer Res; 2001 Dec; 61(23):8422-8. PubMed ID: 11731422
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chemoprotective and toxic potentials of synthetic and natural chalcones and dihydrochalcones in vitro.
    Forejtníková H; Lunerová K; Kubínová R; Jankovská D; Marek R; Kares R; Suchý V; Vondrácek J; Machala M
    Toxicology; 2005 Mar; 208(1):81-93. PubMed ID: 15664435
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anthracycline metabolism and toxicity in human myocardium: comparisons between doxorubicin, epirubicin, and a novel disaccharide analogue with a reduced level of formation and [4Fe-4S] reactivity of its secondary alcohol metabolite.
    Minotti G; Licata S; Saponiero A; Menna P; Calafiore AM; Di Giammarco G; Liberi G; Animati F; Cipollone A; Manzini S; Maggi CA
    Chem Res Toxicol; 2000 Dec; 13(12):1336-41. PubMed ID: 11123976
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cardiotoxicity and comparative pharmacokinetics of six anthracyclines in the rabbit.
    Jaenke RS; Deprez-DeCampeneere D; Trouet A
    Cancer Res; 1980 Oct; 40(10):3530-6. PubMed ID: 6934026
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural requirement of chalcones for the inhibitory activity of interleukin-5.
    Yang HM; Shin HR; Cho SH; Bang SC; Song GY; Ju JH; Kim MK; Lee SH; Ryu JC; Kim Y; Jung SH
    Bioorg Med Chem; 2007 Jan; 15(1):104-11. PubMed ID: 17064909
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Paclitaxel and docetaxel stimulation of doxorubicinol formation in the human heart: implications for cardiotoxicity of doxorubicin-taxane chemotherapies.
    Salvatorelli E; Menna P; Cascegna S; Liberi G; Calafiore AM; Gianni L; Minotti G
    J Pharmacol Exp Ther; 2006 Jul; 318(1):424-33. PubMed ID: 16614166
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of quinones and flavonoids on the reduction of all-trans retinal to all-trans retinol in pig heart.
    Shimada H; Hirashima T; Imamura Y
    Eur J Pharmacol; 2006 Jul; 540(1-3):46-52. PubMed ID: 16730705
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Defective taxane stimulation of epirubicinol formation in the human heart: insight into the cardiac tolerability of epirubicin-taxane chemotherapies.
    Salvatorelli E; Menna P; Gianni L; Minotti G
    J Pharmacol Exp Ther; 2007 Feb; 320(2):790-800. PubMed ID: 17135345
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anthracyclines and their metabolism in human liver microsomes and the participation of the new microsomal carbonyl reductase.
    Skarka A; Skarydová L; Stambergová H; Wsól V
    Chem Biol Interact; 2011 May; 191(1-3):66-74. PubMed ID: 21185270
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibitory activities of prenylated flavonoids from Sophora flavescens against aldose reductase and generation of advanced glycation endproducts.
    Jung HA; Yoon NY; Kang SS; Kim YS; Choi JS
    J Pharm Pharmacol; 2008 Sep; 60(9):1227-36. PubMed ID: 18718128
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacokinetic characterization of amrubicin cardiac safety in an ex vivo human myocardial strip model. II. Amrubicin shows metabolic advantages over doxorubicin and epirubicin.
    Salvatorelli E; Menna P; Gonzalez Paz O; Surapaneni S; Aukerman SL; Chello M; Covino E; Sung V; Minotti G
    J Pharmacol Exp Ther; 2012 May; 341(2):474-83. PubMed ID: 22338034
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.