BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

594 related articles for article (PubMed ID: 17114044)

  • 21. Clinical implications of gene discovery in Parkinson's disease and parkinsonism.
    Wider C; Foroud T; Wszolek ZK
    Mov Disord; 2010; 25 Suppl 1():S15-20. PubMed ID: 20187245
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration.
    Smith WW; Pei Z; Jiang H; Moore DJ; Liang Y; West AB; Dawson VL; Dawson TM; Ross CA
    Proc Natl Acad Sci U S A; 2005 Dec; 102(51):18676-81. PubMed ID: 16352719
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Parkinsonism, Lrrk2 G2019S, and tau neuropathology.
    Rajput A; Dickson DW; Robinson CA; Ross OA; Dächsel JC; Lincoln SJ; Cobb SA; Rajput ML; Farrer MJ
    Neurology; 2006 Oct; 67(8):1506-8. PubMed ID: 17060589
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Isolated nigral degeneration without pathological protein aggregation in autopsied brains with LRRK2 p.R1441H homozygous and heterozygous mutations.
    Takanashi M; Funayama M; Matsuura E; Yoshino H; Li Y; Tsuyama S; Takashima H; Nishioka K; Hattori N
    Acta Neuropathol Commun; 2018 Oct; 6(1):105. PubMed ID: 30333048
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Abnormal localization of leucine-rich repeat kinase 2 to the endosomal-lysosomal compartment in lewy body disease.
    Higashi S; Moore DJ; Yamamoto R; Minegishi M; Sato K; Togo T; Katsuse O; Uchikado H; Furukawa Y; Hino H; Kosaka K; Emson PC; Wada K; Dawson VL; Dawson TM; Arai H; Iseki E
    J Neuropathol Exp Neurol; 2009 Sep; 68(9):994-1005. PubMed ID: 19680143
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Biochemical and pathological characterization of Lrrk2.
    Giasson BI; Covy JP; Bonini NM; Hurtig HI; Farrer MJ; Trojanowski JQ; Van Deerlin VM
    Ann Neurol; 2006 Feb; 59(2):315-22. PubMed ID: 16437584
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain.
    Civiero L; Cirnaru MD; Beilina A; Rodella U; Russo I; Belluzzi E; Lobbestael E; Reyniers L; Hondhamuni G; Lewis PA; Van den Haute C; Baekelandt V; Bandopadhyay R; Bubacco L; Piccoli G; Cookson MR; Taymans JM; Greggio E
    J Neurochem; 2015 Dec; 135(6):1242-56. PubMed ID: 26375402
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Leucine-rich repeat kinase 2 (LRRK2)/PARK8 possesses GTPase activity that is altered in familial Parkinson's disease R1441C/G mutants.
    Li X; Tan YC; Poulose S; Olanow CW; Huang XY; Yue Z
    J Neurochem; 2007 Oct; 103(1):238-47. PubMed ID: 17623048
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity.
    West AB; Moore DJ; Choi C; Andrabi SA; Li X; Dikeman D; Biskup S; Zhang Z; Lim KL; Dawson VL; Dawson TM
    Hum Mol Genet; 2007 Jan; 16(2):223-32. PubMed ID: 17200152
    [TBL] [Abstract][Full Text] [Related]  

  • 30. LRRK2 guides the actin cytoskeleton at growth cones together with ARHGEF7 and Tropomyosin 4.
    Häbig K; Gellhaar S; Heim B; Djuric V; Giesert F; Wurst W; Walter C; Hentrich T; Riess O; Bonin M
    Biochim Biophys Acta; 2013 Dec; 1832(12):2352-67. PubMed ID: 24075941
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Parkinsonism genes: culprits and clues.
    Abeliovich A; Flint Beal M
    J Neurochem; 2006 Nov; 99(4):1062-72. PubMed ID: 16836655
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A Drosophila model for LRRK2-linked parkinsonism.
    Liu Z; Wang X; Yu Y; Li X; Wang T; Jiang H; Ren Q; Jiao Y; Sawa A; Moran T; Ross CA; Montell C; Smith WW
    Proc Natl Acad Sci U S A; 2008 Feb; 105(7):2693-8. PubMed ID: 18258746
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Targeting the cannabinoid CB2 receptor to attenuate the progression of motor deficits in LRRK2-transgenic mice.
    Palomo-Garo C; Gómez-Gálvez Y; García C; Fernández-Ruiz J
    Pharmacol Res; 2016 Aug; 110():181-192. PubMed ID: 27063942
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology.
    Zimprich A; Biskup S; Leitner P; Lichtner P; Farrer M; Lincoln S; Kachergus J; Hulihan M; Uitti RJ; Calne DB; Stoessl AJ; Pfeiffer RF; Patenge N; Carbajal IC; Vieregge P; Asmus F; Müller-Myhsok B; Dickson DW; Meitinger T; Strom TM; Wszolek ZK; Gasser T
    Neuron; 2004 Nov; 44(4):601-7. PubMed ID: 15541309
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Analysis of 14 LRRK2 mutations in Parkinson's plus syndromes and late-onset Parkinson's disease.
    Tan EK; Skipper L; Chua E; Wong MC; Pavanni R; Bonnard C; Kolatkar P; Liu JJ
    Mov Disord; 2006 Jul; 21(7):997-1001. PubMed ID: 16602113
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Olfactory heterogeneity in LRRK2 related Parkinsonism.
    Silveira-Moriyama L; Munhoz RP; de J Carvalho M; Raskin S; Rogaeva E; de C Aguiar P; Bressan RA; Felicio AC; Barsottini OG; Andrade LA; Chien HF; Bonifati V; Barbosa ER; Teive HA; Lees AJ
    Mov Disord; 2010 Dec; 25(16):2879-83. PubMed ID: 20818658
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Developmental regulation of leucine-rich repeat kinase 1 and 2 expression in the brain and other rodent and human organs: Implications for Parkinson's disease.
    Westerlund M; Belin AC; Anvret A; Bickford P; Olson L; Galter D
    Neuroscience; 2008 Mar; 152(2):429-36. PubMed ID: 18272292
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The industrial solvent trichloroethylene induces LRRK2 kinase activity and dopaminergic neurodegeneration in a rat model of Parkinson's disease.
    De Miranda BR; Castro SL; Rocha EM; Bodle CR; Johnson KE; Greenamyre JT
    Neurobiol Dis; 2021 Jun; 153():105312. PubMed ID: 33636387
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Co-occurrence of sporadic parkinsonism and late-onset Alzheimer's disease in a Brazilian male with the LRRK2 p.G2019S mutation.
    Santos-Rebouças CB; Abdalla CB; Baldi FJ; Martins PA; Corrêa JC; Gonçalves AP; Cunha MS; Borges MB; Pereira JS; Laks J; Pimentel MM
    Genet Test; 2008 Dec; 12(4):471-3. PubMed ID: 19072560
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Homozygous mutation of the LRRK2 ROC domain as a novel genetic model of parkinsonism.
    Chen ML; Wu RM
    J Biomed Sci; 2022 Aug; 29(1):60. PubMed ID: 35965315
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 30.