131 related articles for article (PubMed ID: 17117591)
21. Effects of PKF242-484 and PKF241-466, novel dual inhibitors of TNF-alpha converting enzyme and matrix metalloproteinases, in a model of intestinal reperfusion injury in mice.
Souza DG; Ferreira FL; Fagundes CT; Amaral FA; Vieira AT; Lisboa RA; Andrade MV; Trifilieff A; Teixeira MM
Eur J Pharmacol; 2007 Sep; 571(1):72-80. PubMed ID: 17619015
[TBL] [Abstract][Full Text] [Related]
22. Chromen-based TNF-alpha converting enzyme (TACE) inhibitors: design, synthesis, and biological evaluation.
Chun K; Park SK; Kim HM; Choi Y; Kim MH; Park CH; Joe BY; Chun TG; Choi HM; Lee HY; Hong SH; Kim MS; Nam KY; Han G
Bioorg Med Chem; 2008 Jan; 16(1):530-5. PubMed ID: 17936631
[TBL] [Abstract][Full Text] [Related]
23. CYP3A induction by N-hydroxyformamide tumor necrosis factor-alpha converting enzyme/matrix metalloproteinase inhibitors use of a pregname X receptor activation assay and primary hepatocyte culture for assessing induction potential in humans.
Tippin TK; Hamilton G; Moore L; Beaudet EJ; Jolley S; Brodie TA; Andrews RC; Becherer JD; McDougald DL; Gaul MD; Hoivik DJ; Mellon-Kusibab K; Lehmann J; Kliewer S; Novick S; Laethem R; Zhao Z; LeCluyse EL
Drug Metab Dispos; 2003 Jul; 31(7):870-7. PubMed ID: 12814963
[TBL] [Abstract][Full Text] [Related]
24. Combination of tumor necrosis factor-alpha ablation and matrix metalloproteinase inhibition prevents heart failure after pressure overload in tissue inhibitor of metalloproteinase-3 knock-out mice.
Kassiri Z; Oudit GY; Sanchez O; Dawood F; Mohammed FF; Nuttall RK; Edwards DR; Liu PP; Backx PH; Khokha R
Circ Res; 2005 Aug; 97(4):380-90. PubMed ID: 16037568
[TBL] [Abstract][Full Text] [Related]
25. Benzodiazepine inhibitors of the MMPs and TACE. Part 2.
Levin JI; Nelson FC; Delos Santos E; Du MT; MacEwan G; Chen JM; Ayral-Kaloustian S; Xu J; Jin G; Cummons T; Barone D
Bioorg Med Chem Lett; 2004 Aug; 14(16):4147-51. PubMed ID: 15261259
[TBL] [Abstract][Full Text] [Related]
26. Conversion of potent MMP inhibitors into selective TACE inhibitors.
Cherney RJ; King BW; Gilmore JL; Liu RQ; Covington MB; Duan JJ; Decicco CP
Bioorg Med Chem Lett; 2006 Feb; 16(4):1028-31. PubMed ID: 16289878
[TBL] [Abstract][Full Text] [Related]
27. A rat pharmacokinetic/pharmacodynamic model for assessment of lipopolysaccharide-induced tumor necrosis factor-alpha production.
Wang Q; Zhang Y; Hall JP; Lin LL; Raut U; Mollova N; Green N; Cuozzo J; Chesley S; Xu X; Levin JI; Patel VS
J Pharmacol Toxicol Methods; 2007; 56(1):67-71. PubMed ID: 17391989
[TBL] [Abstract][Full Text] [Related]
28. A cassette-dosing approach for improvement of oral bioavailability of dual TACE/MMP inhibitors.
Janser P; Neumann U; Miltz W; Feifel R; Buhl T
Bioorg Med Chem Lett; 2006 May; 16(10):2632-6. PubMed ID: 16516469
[TBL] [Abstract][Full Text] [Related]
29. Pharmacological profile of PKF242-484 and PKF241-466, novel dual inhibitors of TNF-alpha converting enzyme and matrix metalloproteinases, in models of airway inflammation.
Trifilieff A; Walker C; Keller T; Kottirsch G; Neumann U
Br J Pharmacol; 2002 Apr; 135(7):1655-64. PubMed ID: 11934805
[TBL] [Abstract][Full Text] [Related]
30. NCX-701. NicOx.
Joshi GP
Curr Opin Investig Drugs; 2004 Jul; 5(7):755-9. PubMed ID: 15298073
[TBL] [Abstract][Full Text] [Related]
31. Harnessing the natural inhibitory domain to control TNFα Converting Enzyme (TACE) activity in vivo.
Wong E; Cohen T; Romi E; Levin M; Peleg Y; Arad U; Yaron A; Milla ME; Sagi I
Sci Rep; 2016 Dec; 6():35598. PubMed ID: 27982031
[TBL] [Abstract][Full Text] [Related]
32. Hydantoins, triazolones, and imidazolones as selective non-hydroxamate inhibitors of tumor necrosis factor-alpha converting enzyme (TACE).
Sheppeck JE; Gilmore JL; Tebben A; Xue CB; Liu RQ; Decicco CP; Duan JJ
Bioorg Med Chem Lett; 2007 May; 17(10):2769-74. PubMed ID: 17368021
[TBL] [Abstract][Full Text] [Related]
33. BMS-561392. Bristol-Myers Squibb.
Grootveld M; McDermott MF
Curr Opin Investig Drugs; 2003 May; 4(5):598-602. PubMed ID: 12833656
[TBL] [Abstract][Full Text] [Related]
34. Etanercept Immunex.
Yung RL
Curr Opin Investig Drugs; 2001 Feb; 2(2):216-21. PubMed ID: 11816834
[TBL] [Abstract][Full Text] [Related]
35. Non-hydroxamate 5-phenylpyrimidine-2,4,6-trione derivatives as selective inhibitors of tumor necrosis factor-alpha converting enzyme.
Duan JJ; Lu Z; Wasserman ZR; Liu RQ; Covington MB; Decicco CP
Bioorg Med Chem Lett; 2005 Jun; 15(12):2970-3. PubMed ID: 15908214
[TBL] [Abstract][Full Text] [Related]
36. Inhibition of tumor necrosis factor-alpha (TNF-alpha) production and arthritis in the rat by GW3333, a dual inhibitor of TNF-alpha-converting enzyme and matrix metalloproteinases.
Conway JG; Andrews RC; Beaudet B; Bickett DM; Boncek V; Brodie TA; Clark RL; Crumrine RC; Leenitzer MA; McDougald DL; Han B; Hedeen K; Lin P; Milla M; Moss M; Pink H; Rabinowitz MH; Tippin T; Scates PW; Selph J; Stimpson SA; Warner J; Becherer JD
J Pharmacol Exp Ther; 2001 Sep; 298(3):900-8. PubMed ID: 11504783
[TBL] [Abstract][Full Text] [Related]
37. Design and synthesis of butynyloxyphenyl beta-sulfone piperidine hydroxamates as TACE inhibitors.
Park K; Aplasca A; Du MT; Sun L; Zhu Y; Zhang Y; Levin JI
Bioorg Med Chem Lett; 2006 Aug; 16(15):3927-31. PubMed ID: 16723229
[TBL] [Abstract][Full Text] [Related]
38. Prevention of progressive joint destruction in collagen-induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR255031.
Ishikawa T; Nishigaki F; Miyata S; Hirayama Y; Minoura K; Imanishi J; Neya M; Mizutani T; Imamura Y; Naritomi Y; Murai H; Ohkubo Y; Kagayama A; Mutoh S
Br J Pharmacol; 2005 Jan; 144(1):133-43. PubMed ID: 15644877
[TBL] [Abstract][Full Text] [Related]
39. Design and synthesis of 3,3-piperidine hydroxamate analogs as selective TACE inhibitors.
Lombart HG; Feyfant E; Joseph-McCarthy D; Huang A; Lovering F; Sun L; Zhu Y; Zeng C; Zhang Y; Levin J
Bioorg Med Chem Lett; 2007 Aug; 17(15):4333-7. PubMed ID: 17531482
[TBL] [Abstract][Full Text] [Related]
40. Potent, selective, orally bioavailable inhibitors of tumor necrosis factor-alpha converting enzyme (TACE): discovery of indole, benzofuran, imidazopyridine and pyrazolopyridine P1' substituents.
Lu Z; Ott GR; Anand R; Liu RQ; Covington MB; Vaddi K; Qian M; Newton RC; Christ DD; Trzaskos J; Duan JJ
Bioorg Med Chem Lett; 2008 Mar; 18(6):1958-62. PubMed ID: 18282708
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
