193 related articles for article (PubMed ID: 17118344)
1. Irofulven induces replication-dependent CHK2 activation related to p53 status.
Wang Y; Wiltshire T; Senft J; Reed E; Wang W
Biochem Pharmacol; 2007 Feb; 73(4):469-80. PubMed ID: 17118344
[TBL] [Abstract][Full Text] [Related]
2. ATM-dependent CHK2 activation induced by anticancer agent, irofulven.
Wang J; Wiltshire T; Wang Y; Mikell C; Burks J; Cunningham C; Van Laar ES; Waters SJ; Reed E; Wang W
J Biol Chem; 2004 Sep; 279(38):39584-92. PubMed ID: 15269203
[TBL] [Abstract][Full Text] [Related]
3. BRCA1 contributes to cell cycle arrest and chemoresistance in response to the anticancer agent irofulven.
Wiltshire T; Senft J; Wang Y; Konat GW; Wenger SL; Reed E; Wang W
Mol Pharmacol; 2007 Apr; 71(4):1051-60. PubMed ID: 17229870
[TBL] [Abstract][Full Text] [Related]
4. Chk2 is required for optimal mitotic delay in response to irradiation-induced DNA damage incurred in G2 phase.
Rainey MD; Black EJ; Zachos G; Gillespie DA
Oncogene; 2008 Feb; 27(7):896-906. PubMed ID: 17684483
[TBL] [Abstract][Full Text] [Related]
5. Fanconi anemia D2 protein confers chemoresistance in response to the anticancer agent, irofulven.
Wang Y; Wiltshire T; Senft J; Wenger SL; Reed E; Wang W
Mol Cancer Ther; 2006 Dec; 5(12):3153-61. PubMed ID: 17172419
[TBL] [Abstract][Full Text] [Related]
6. UCN-01 inhibits p53 up-regulation and abrogates gamma-radiation-induced G(2)-M checkpoint independently of p53 by targeting both of the checkpoint kinases, Chk2 and Chk1.
Yu Q; La Rose J; Zhang H; Takemura H; Kohn KW; Pommier Y
Cancer Res; 2002 Oct; 62(20):5743-8. PubMed ID: 12384533
[TBL] [Abstract][Full Text] [Related]
7. Knockdown of Chk1 sensitizes human colon carcinoma HCT116 cells in a p53-dependent manner to lidamycin through abrogation of a G2/M checkpoint and induction of apoptosis.
Pan Y; Ren KH; He HW; Shao RG
Cancer Biol Ther; 2009 Aug; 8(16):1559-66. PubMed ID: 19502782
[TBL] [Abstract][Full Text] [Related]
8. Topoisomerase inhibitor coralyne photosensitizes DNA, leading to elicitation of Chk2-dependent S-phase checkpoint and p53-independent apoptosis in cancer cells.
Patro BS; Maity B; Chattopadhyay S
Antioxid Redox Signal; 2010 Apr; 12(8):945-60. PubMed ID: 19922265
[TBL] [Abstract][Full Text] [Related]
9. E2F1-dependent pathways are involved in amonafide analogue 7-d-induced DNA damage, G2/M arrest, and apoptosis in p53-deficient K562 cells.
Li Y; Shao J; Shen K; Xu Y; Liu J; Qian X
J Cell Biochem; 2012 Oct; 113(10):3165-77. PubMed ID: 22593008
[TBL] [Abstract][Full Text] [Related]
10. DNA damage-induced activation of p53 by the checkpoint kinase Chk2.
Hirao A; Kong YY; Matsuoka S; Wakeham A; Ruland J; Yoshida H; Liu D; Elledge SJ; Mak TW
Science; 2000 Mar; 287(5459):1824-7. PubMed ID: 10710310
[TBL] [Abstract][Full Text] [Related]
11. DNA damage and p53 induction do not cause ZD1694-induced cell cycle arrest in human colon carcinoma cells.
Matsui SI; Arredondo MA; Wrzosek C; Rustum YM
Cancer Res; 1996 Oct; 56(20):4715-23. PubMed ID: 8840989
[TBL] [Abstract][Full Text] [Related]
12. High osmolality activates the G1 and G2 cell cycle checkpoints and affects the DNA integrity of nucleus pulposus intervertebral disc cells triggering an enhanced DNA repair response.
Mavrogonatou E; Kletsas D
DNA Repair (Amst); 2009 Aug; 8(8):930-43. PubMed ID: 19535302
[TBL] [Abstract][Full Text] [Related]
13. The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe.
Castedo M; Perfettini JL; Roumier T; Yakushijin K; Horne D; Medema R; Kroemer G
Oncogene; 2004 May; 23(25):4353-61. PubMed ID: 15048074
[TBL] [Abstract][Full Text] [Related]
14. Eupatilin, a dietary flavonoid, induces G2/M cell cycle arrest in human endometrial cancer cells.
Cho JH; Lee JG; Yang YI; Kim JH; Ahn JH; Baek NI; Lee KT; Choi JH
Food Chem Toxicol; 2011 Aug; 49(8):1737-44. PubMed ID: 21554918
[TBL] [Abstract][Full Text] [Related]
15. Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53.
Chehab NH; Malikzay A; Appel M; Halazonetis TD
Genes Dev; 2000 Feb; 14(3):278-88. PubMed ID: 10673500
[TBL] [Abstract][Full Text] [Related]
16. Hedamycin, a DNA alkylator, induces (gamma)H2AX and chromosome aberrations: involvement of phosphatidylinositol 3-kinase-related kinases and DNA replication fork movement.
Tu LC; Matsui SI; Beerman TA
Mol Cancer Ther; 2005 Aug; 4(8):1175-85. PubMed ID: 16093433
[TBL] [Abstract][Full Text] [Related]
17. E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis.
Powers JT; Hong S; Mayhew CN; Rogers PM; Knudsen ES; Johnson DG
Mol Cancer Res; 2004 Apr; 2(4):203-14. PubMed ID: 15140942
[TBL] [Abstract][Full Text] [Related]
18. Cell cycle effects and induction of premitotic apoptosis by irofulven in synchronized cancer cells.
Woynarowski JM; Woynarowska BA; Trevino AV; Salinas R; Herman TS; Waters SJ; Macdonald JR
Cancer Biol Ther; 2004 Nov; 3(11):1137-42; discussion 1143-4. PubMed ID: 15467441
[TBL] [Abstract][Full Text] [Related]
19. Akt activation suppresses Chk2-mediated, methylating agent-induced G2 arrest and protects from temozolomide-induced mitotic catastrophe and cellular senescence.
Hirose Y; Katayama M; Mirzoeva OK; Berger MS; Pieper RO
Cancer Res; 2005 Jun; 65(11):4861-9. PubMed ID: 15930307
[TBL] [Abstract][Full Text] [Related]
20. Activation of checkpoint kinase 2 by 3,3'-diindolylmethane is required for causing G2/M cell cycle arrest in human ovarian cancer cells.
Kandala PK; Srivastava SK
Mol Pharmacol; 2010 Aug; 78(2):297-309. PubMed ID: 20444961
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
