BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

369 related articles for article (PubMed ID: 17121922)

  • 1. The Mre11/Rad50/Nbs1 complex interacts with the mismatch repair system and contributes to temozolomide-induced G2 arrest and cytotoxicity.
    Mirzoeva OK; Kawaguchi T; Pieper RO
    Mol Cancer Ther; 2006 Nov; 5(11):2757-66. PubMed ID: 17121922
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
    Williams RS; Williams JS; Tainer JA
    Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks.
    Robison JG; Elliott J; Dixon K; Oakley GG
    J Biol Chem; 2004 Aug; 279(33):34802-10. PubMed ID: 15180989
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Variations in Mre11/Rad50/Nbs1 status and DNA damage-induced S-phase arrest in the cell lines of the NCI60 panel.
    Garner KM; Eastman A
    BMC Cancer; 2011 May; 11():206:1-13. PubMed ID: 21619594
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transcription-coupled DNA double-strand breaks are mediated via the nucleotide excision repair and the Mre11-Rad50-Nbs1 complex.
    Guirouilh-Barbat J; Redon C; Pommier Y
    Mol Biol Cell; 2008 Sep; 19(9):3969-81. PubMed ID: 18632984
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MRE11-RAD50-NBS1 complex dictates DNA repair independent of H2AX.
    Yuan J; Chen J
    J Biol Chem; 2010 Jan; 285(2):1097-104. PubMed ID: 19910469
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Intracellular redistribution and modification of proteins of the Mre11/Rad50/Nbs1 DNA repair complex following irradiation and heat-shock.
    Seno JD; Dynlacht JR
    J Cell Physiol; 2004 May; 199(2):157-70. PubMed ID: 15039997
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.
    Chen L; Nievera CJ; Lee AY; Wu X
    J Biol Chem; 2008 Mar; 283(12):7713-20. PubMed ID: 18171670
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Replication protein A is required for etoposide-induced assembly of MRE11/RAD50/NBS1 complex repair foci.
    Robison JG; Bissler JJ; Dixon K
    Cell Cycle; 2007 Oct; 6(19):2408-16. PubMed ID: 17700070
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lack of MRE11-RAD50-NBS1 (MRN) complex detection occurs frequently in low-grade epithelial ovarian cancer.
    Brandt S; Samartzis EP; Zimmermann AK; Fink D; Moch H; Noske A; Dedes KJ
    BMC Cancer; 2017 Jan; 17(1):44. PubMed ID: 28073364
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.
    Takemura H; Rao VA; Sordet O; Furuta T; Miao ZH; Meng L; Zhang H; Pommier Y
    J Biol Chem; 2006 Oct; 281(41):30814-23. PubMed ID: 16905549
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Constitutive phosphorylation of MDC1 physically links the MRE11-RAD50-NBS1 complex to damaged chromatin.
    Spycher C; Miller ES; Townsend K; Pavic L; Morrice NA; Janscak P; Stewart GS; Stucki M
    J Cell Biol; 2008 Apr; 181(2):227-40. PubMed ID: 18411308
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The transcriptional histone acetyltransferase cofactor TRRAP associates with the MRN repair complex and plays a role in DNA double-strand break repair.
    Robert F; Hardy S; Nagy Z; Baldeyron C; Murr R; Déry U; Masson JY; Papadopoulo D; Herceg Z; Tora L
    Mol Cell Biol; 2006 Jan; 26(2):402-12. PubMed ID: 16382133
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex.
    Lee KY; Im JS; Shibata E; Park J; Handa N; Kowalczykowski SC; Dutta A
    Nat Commun; 2015 Jul; 6():7744. PubMed ID: 26215093
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A divalent FHA/BRCT-binding mechanism couples the MRE11-RAD50-NBS1 complex to damaged chromatin.
    Hari FJ; Spycher C; Jungmichel S; Pavic L; Stucki M
    EMBO Rep; 2010 May; 11(5):387-92. PubMed ID: 20224574
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaks.
    Wang Q; Goldstein M; Alexander P; Wakeman TP; Sun T; Feng J; Lou Z; Kastan MB; Wang XF
    EMBO J; 2014 Apr; 33(8):862-77. PubMed ID: 24534091
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mre11-Rad50-Nbs1 complex is activated by hypertonicity.
    Sheen MR; Kim SW; Jung JY; Ahn JY; Rhee JG; Kwon HM; Woo SK
    Am J Physiol Renal Physiol; 2006 Nov; 291(5):F1014-20. PubMed ID: 16788144
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Deubiquitinase USP2 stabilizes the MRE11-RAD50-NBS1 complex at DNA double-strand break sites by counteracting the ubiquitination of NBS1.
    Kim H; Kim D; Choi H; Shin G; Lee JK
    J Biol Chem; 2023 Jan; 299(1):102752. PubMed ID: 36436562
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Smad7 enhances ATM activity by facilitating the interaction between ATM and Mre11-Rad50-Nbs1 complex in DNA double-strand break repair.
    Park S; Kang JM; Kim SJ; Kim H; Hong S; Lee YJ; Kim SJ
    Cell Mol Life Sci; 2015 Feb; 72(3):583-596. PubMed ID: 25063542
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NBS1 is regulated by two kind of mechanisms: ATM-dependent complex formation with MRE11 and RAD50, and cell cycle-dependent degradation of protein.
    Zhou H; Kawamura K; Yanagihara H; Kobayashi J; Zhang-Akiyama QM
    J Radiat Res; 2017 Jul; 58(4):487-494. PubMed ID: 28369484
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.