BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 17121941)

  • 1. Benzyl isothiocyanate-induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak.
    Xiao D; Vogel V; Singh SV
    Mol Cancer Ther; 2006 Nov; 5(11):2931-45. PubMed ID: 17121941
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Benzyl isothiocyanate targets mitochondrial respiratory chain to trigger reactive oxygen species-dependent apoptosis in human breast cancer cells.
    Xiao D; Powolny AA; Singh SV
    J Biol Chem; 2008 Oct; 283(44):30151-63. PubMed ID: 18768478
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Short-form RON overexpression augments benzyl isothiocyanate-induced apoptosis in human breast cancer cells.
    Sehrawat A; Singh SV
    Mol Carcinog; 2016 May; 55(5):473-85. PubMed ID: 25857724
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Critical role of p53 upregulated modulator of apoptosis in benzyl isothiocyanate-induced apoptotic cell death.
    Antony ML; Kim SH; Singh SV
    PLoS One; 2012; 7(2):e32267. PubMed ID: 22359675
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bax and Bak are required for apoptosis induction by sulforaphane, a cruciferous vegetable-derived cancer chemopreventive agent.
    Choi S; Singh SV
    Cancer Res; 2005 Mar; 65(5):2035-43. PubMed ID: 15753404
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.
    Huang SH; Wu LW; Huang AC; Yu CC; Lien JC; Huang YP; Yang JS; Yang JH; Hsiao YP; Wood WG; Yu CS; Chung JG
    J Agric Food Chem; 2012 Jan; 60(2):665-75. PubMed ID: 22148415
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Caspase-dependent apoptosis induction by phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent, is mediated by Bak and Bax.
    Xiao D; Zeng Y; Choi S; Lew KL; Nelson JB; Singh SV
    Clin Cancer Res; 2005 Apr; 11(7):2670-9. PubMed ID: 15814648
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cell cycle arrest, apoptosis induction and inhibition of nuclear factor kappa B activation in anti-proliferative activity of benzyl isothiocyanate against human pancreatic cancer cells.
    Srivastava SK; Singh SV
    Carcinogenesis; 2004 Sep; 25(9):1701-9. PubMed ID: 15117814
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells.
    Wu CL; Huang AC; Yang JS; Liao CL; Lu HF; Chou ST; Ma CY; Hsia TC; Ko YC; Chung JG
    J Orthop Res; 2011 Aug; 29(8):1199-209. PubMed ID: 21374707
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of mitochondrial fusion is an early and critical event in breast cancer cell apoptosis by dietary chemopreventative benzyl isothiocyanate.
    Sehrawat A; Croix CS; Baty CJ; Watkins S; Tailor D; Singh RP; Singh SV
    Mitochondrion; 2016 Sep; 30():67-77. PubMed ID: 27374852
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species.
    Hahm ER; Moura MB; Kelley EE; Van Houten B; Shiva S; Singh SV
    PLoS One; 2011; 6(8):e23354. PubMed ID: 21853114
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells.
    Xiao D; Johnson CS; Trump DL; Singh SV
    Mol Cancer Ther; 2004 May; 3(5):567-75. PubMed ID: 15141014
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Caspase-dependent apoptosis induction by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak.
    Singh SV; Zeng Y; Xiao D; Vogel VG; Nelson JB; Dhir R; Tripathi YB
    Mol Cancer Ther; 2005 Nov; 4(11):1747-54. PubMed ID: 16275996
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Benzyl isothiocyanate causes FoxO1-mediated autophagic death in human breast cancer cells.
    Xiao D; Bommareddy A; Kim SH; Sehrawat A; Hahm ER; Singh SV
    PLoS One; 2012; 7(3):e32597. PubMed ID: 22457718
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Benzyl isothiocyanate (BITC) induces apoptosis of GBM 8401 human brain glioblastoma multiforms cells via activation of caspase-8/Bid and the reactive oxygen species-dependent mitochondrial pathway.
    Shang HS; Shih YL; Lu TJ; Lee CH; Hsueh SC; Chou YC; Lu HF; Liao NC; Chung JG
    Environ Toxicol; 2016 Dec; 31(12):1751-1760. PubMed ID: 28675694
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Benzyl isothiocyanate inhibits epithelial-mesenchymal transition in cultured and xenografted human breast cancer cells.
    Sehrawat A; Singh SV
    Cancer Prev Res (Phila); 2011 Jul; 4(7):1107-17. PubMed ID: 21464039
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cancer-selective death of human breast cancer cells by leelamine is mediated by bax and bak activation.
    Sehrawat A; Kim SH; Hahm ER; Arlotti JA; Eiseman J; Shiva SS; Rigatti LH; Singh SV
    Mol Carcinog; 2017 Feb; 56(2):337-348. PubMed ID: 27149078
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p53-Independent apoptosis by benzyl isothiocyanate in human breast cancer cells is mediated by suppression of XIAP expression.
    Kim SH; Singh SV
    Cancer Prev Res (Phila); 2010 Jun; 3(6):718-26. PubMed ID: 20484174
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells.
    Sahu RP; Zhang R; Batra S; Shi Y; Srivastava SK
    Carcinogenesis; 2009 Oct; 30(10):1744-53. PubMed ID: 19549704
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines.
    Pledgie-Tracy A; Sobolewski MD; Davidson NE
    Mol Cancer Ther; 2007 Mar; 6(3):1013-21. PubMed ID: 17339367
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.