These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

298 related articles for article (PubMed ID: 17125260)

  • 1. Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y2, P2Y4, and P2Y6 receptors.
    El-Tayeb A; Qi A; Müller CE
    J Med Chem; 2006 Nov; 49(24):7076-87. PubMed ID: 17125260
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors.
    Kim HS; Ravi RG; Marquez VE; Maddileti S; Wihlborg AK; Erlinge D; Malmsjö M; Boyer JL; Harden TK; Jacobson KA
    J Med Chem; 2002 Jan; 45(1):208-18. PubMed ID: 11754592
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure activity and molecular modeling analyses of ribose- and base-modified uridine 5'-triphosphate analogues at the human P2Y2 and P2Y4 receptors.
    Jacobson KA; Costanzi S; Ivanov AA; Tchilibon S; Besada P; Gao ZG; Maddileti S; Harden TK
    Biochem Pharmacol; 2006 Feb; 71(4):540-9. PubMed ID: 16359641
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Uridine nucleotide selectivity of three phospholipase C-activating P2 receptors: identification of a UDP-selective, a UTP-selective, and an ATP- and UTP-specific receptor.
    Nicholas RA; Watt WC; Lazarowski ER; Li Q; Harden K
    Mol Pharmacol; 1996 Aug; 50(2):224-9. PubMed ID: 8700127
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural modifications of UMP, UDP, and UTP leading to subtype-selective agonists for P2Y2, P2Y4, and P2Y6 receptors.
    El-Tayeb A; Qi A; Nicholas RA; Müller CE
    J Med Chem; 2011 Apr; 54(8):2878-90. PubMed ID: 21417463
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evidence for the expression of multiple uracil nucleotide-stimulated P2 receptors coupled to smooth muscle contraction in porcine isolated arteries.
    Rayment SJ; Latif ML; Ralevic V; Alexander SP
    Br J Pharmacol; 2007 Mar; 150(5):604-12. PubMed ID: 17262017
    [TBL] [Abstract][Full Text] [Related]  

  • 7. P2 receptors activated by uracil nucleotides--an update.
    Brunschweiger A; Müller CE
    Curr Med Chem; 2006; 13(3):289-312. PubMed ID: 16475938
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists.
    Ko H; Carter RL; Cosyn L; Petrelli R; de Castro S; Besada P; Zhou Y; Cappellacci L; Franchetti P; Grifantini M; Van Calenbergh S; Harden TK; Jacobson KA
    Bioorg Med Chem; 2008 Jun; 16(12):6319-32. PubMed ID: 18514530
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential regulation of the uridine nucleotide-activated P2Y4 and P2Y6 receptors. SER-333 and SER-334 in the carboxyl terminus are involved in agonist-dependent phosphorylation desensitization and internalization of the P2Y4 receptor.
    Brinson AE; Harden TK
    J Biol Chem; 2001 Apr; 276(15):11939-48. PubMed ID: 11114308
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pharmacological and second messenger signalling selectivities of cloned P2Y receptors.
    Nicholas RA; Lazarowski ER; Watt WC; Li Q; Boyer J; Harden TK
    J Auton Pharmacol; 1996 Dec; 16(6):319-23. PubMed ID: 9131407
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Apical P2Y4 purinergic receptor controls K+ secretion by vestibular dark cell epithelium.
    Marcus DC; Scofield MA
    Am J Physiol Cell Physiol; 2001 Jul; 281(1):C282-9. PubMed ID: 11401851
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 5-OMe-uridine-5'-O-(α-boranodiphosphate), a novel nucleotide derivative highly active at the human P2Y(6) receptor protects against death-receptor mediated glial apoptosis.
    Haas M; Ginsburg-Shmuel T; Fischer B; Reiser G
    Neurosci Lett; 2014 Aug; 578():80-4. PubMed ID: 24970757
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular modeling of the human P2Y2 receptor and design of a selective agonist, 2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate.
    Ivanov AA; Ko H; Cosyn L; Maddileti S; Besada P; Fricks I; Costanzi S; Harden TK; Calenbergh SV; Jacobson KA
    J Med Chem; 2007 Mar; 50(6):1166-76. PubMed ID: 17302398
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pharmacological characterization of nucleotide P2Y receptors on endothelial cells of the mouse aorta.
    Guns PJ; Korda A; Crauwels HM; Van Assche T; Robaye B; Boeynaems JM; Bult H
    Br J Pharmacol; 2005 Sep; 146(2):288-95. PubMed ID: 15997227
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor.
    Besada P; Shin DH; Costanzi S; Ko H; Mathé C; Gagneron J; Gosselin G; Maddileti S; Harden TK; Jacobson KA
    J Med Chem; 2006 Sep; 49(18):5532-43. PubMed ID: 16942026
    [TBL] [Abstract][Full Text] [Related]  

  • 16. P2Y6 nucleotide receptors activate NF-kappaB and increase survival of osteoclasts.
    Korcok J; Raimundo LN; Du X; Sims SM; Dixon SJ
    J Biol Chem; 2005 Apr; 280(17):16909-15. PubMed ID: 15722352
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanisms of agonist-dependent and -independent desensitization of a recombinant P2Y2 nucleotide receptor.
    Otero M; Garrad RC; Velázquez B; Hernández-Pérez MG; Camden JM; Erb L; Clarke LL; Turner JT; Weisman GA; González FA
    Mol Cell Biochem; 2000 Feb; 205(1-2):115-23. PubMed ID: 10821429
    [TBL] [Abstract][Full Text] [Related]  

  • 18. K+ secretion activated by luminal P2Y2 and P2Y4 receptors in mouse colon.
    Matos JE; Robaye B; Boeynaems JM; Beauwens R; Leipziger J
    J Physiol; 2005 Apr; 564(Pt 1):269-79. PubMed ID: 15718265
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacological profiles of cloned mammalian P2Y-receptor subtypes.
    von Kügelgen I
    Pharmacol Ther; 2006 Jun; 110(3):415-32. PubMed ID: 16257449
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Human keratinocytes express multiple P2Y-receptors: evidence for functional P2Y1, P2Y2, and P2Y4 receptors.
    Burrell HE; Bowler WB; Gallagher JA; Sharpe GR
    J Invest Dermatol; 2003 Mar; 120(3):440-7. PubMed ID: 12603858
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.