BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 17126817)

  • 1. Inducible overexpression of c-Jun in MCF7 cells causes resistance to vinblastine via inhibition of drug-induced apoptosis and senescence at a step subsequent to mitotic arrest.
    Duan L; Sterba K; Kolomeichuk S; Kim H; Brown PH; Chambers TC
    Biochem Pharmacol; 2007 Feb; 73(4):481-90. PubMed ID: 17126817
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The c-Jun NH(2)-terminal protein kinase/AP-1 pathway is required for efficient apoptosis induced by vinblastine.
    Fan M; Goodwin ME; Birrer MJ; Chambers TC
    Cancer Res; 2001 Jun; 61(11):4450-8. PubMed ID: 11389075
    [TBL] [Abstract][Full Text] [Related]  

  • 3. AP-1 activation and altered AP-1 composition in association with increased phosphorylation and expression of specific Jun and Fos family proteins induced by vinblastine in KB-3 cells.
    Berry A; Goodwin M; Moran CL; Chambers TC
    Biochem Pharmacol; 2001 Sep; 62(5):581-91. PubMed ID: 11585055
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Modulation of mitogen-activated protein kinases and phosphorylation of Bcl-2 by vinblastine represent persistent forms of normal fluctuations at G2-M1.
    Fan M; Du L; Stone AA; Gilbert KM; Chambers TC
    Cancer Res; 2000 Nov; 60(22):6403-7. PubMed ID: 11103805
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct signaling pathways of microtubule inhibitors--vinblastine and Taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively.
    Kolomeichuk SN; Terrano DT; Lyle CS; Sabapathy K; Chambers TC
    FEBS J; 2008 Apr; 275(8):1889-99. PubMed ID: 18341588
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Induction of apoptosis by vinblastine via c-Jun autoamplification and p53-independent down-regulation of p21WAF1/CIP1.
    Kolomeichuk SN; Bene A; Upreti M; Dennis RA; Lyle CS; Rajasekaran M; Chambers TC
    Mol Pharmacol; 2008 Jan; 73(1):128-36. PubMed ID: 18094076
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The JNK, ERK and p53 pathways play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide.
    Brantley-Finley C; Lyle CS; Du L; Goodwin ME; Hall T; Szwedo D; Kaushal GP; Chambers TC
    Biochem Pharmacol; 2003 Aug; 66(3):459-69. PubMed ID: 12907245
    [TBL] [Abstract][Full Text] [Related]  

  • 8. p21 functions in a post-mitotic block checkpoint in the apoptotic response to vinblastine.
    Bene A; Chambers TC
    Biochem Biophys Res Commun; 2009 Mar; 380(2):211-7. PubMed ID: 19161984
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evidence that the apoptotic actions of etoposide are independent of c-Jun/activating protein-1-mediated transregulation.
    Jarvis WD; Johnson CR; Fornari FA; Park JS; Dent P; Grant S
    J Pharmacol Exp Ther; 1999 Sep; 290(3):1384-92. PubMed ID: 10454518
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of c-Jun in cellular sensitivity to the microtubule inhibitor vinblastine.
    Obey TB; Lyle CS; Chambers TC
    Biochem Biophys Res Commun; 2005 Oct; 335(4):1179-84. PubMed ID: 16111654
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RRR-alpha-tocopheryl succinate induction of prolonged activation of c-jun amino-terminal kinase and c-jun during induction of apoptosis in human MDA-MB-435 breast cancer cells.
    Yu W; Simmons-Menchaca M; You H; Brown P; Birrer MJ; Sanders BG; Kline K
    Mol Carcinog; 1998 Aug; 22(4):247-57. PubMed ID: 9726817
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Procyanidin induces apoptosis of esophageal adenocarcinoma cells via JNK activation of c-Jun.
    Connor CA; Adriaens M; Pierini R; Johnson IT; Belshaw NJ
    Nutr Cancer; 2014; 66(2):335-41. PubMed ID: 24471892
    [TBL] [Abstract][Full Text] [Related]  

  • 13. c-Jun activation is required for 4-hydroxytamoxifen-induced cell death in breast cancer cells.
    Madeo A; Vinciguerra M; Lappano R; Galgani M; Gasperi-Campani A; Maggiolini M; Musti AM
    Oncogene; 2010 Feb; 29(7):978-91. PubMed ID: 19935718
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transcription factor c-Jun activation represses mdr-1 gene expression.
    Miao ZH; Ding J
    Cancer Res; 2003 Aug; 63(15):4527-32. PubMed ID: 12907627
    [TBL] [Abstract][Full Text] [Related]  

  • 15. NF-kappaB mediates MPP+-induced apoptotic cell death in neuroblastoma cells SH-EP1 through JNK and c-Jun/AP-1.
    Yang HJ; Wang L; Xia YY; Chang PN; Feng ZW
    Neurochem Int; 2010 Jan; 56(1):128-34. PubMed ID: 19778565
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of polyamine analogue cytotoxicity by c-Jun in human MDA-MB-435 cancer cells.
    Huang Y; Keen JC; Hager E; Smith R; Hacker A; Frydman B; Valasinas AL; Reddy VK; Marton LJ; Casero RA; Davidson NE
    Mol Cancer Res; 2004 Feb; 2(2):81-8. PubMed ID: 14985464
    [TBL] [Abstract][Full Text] [Related]  

  • 17. c-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells.
    Minet E; Michel G; Mottet D; Piret JP; Barbieux A; Raes M; Michiels C
    Exp Cell Res; 2001 Apr; 265(1):114-24. PubMed ID: 11281649
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Involvement of activator protein-1 (AP-1) in induction of apoptosis by vitamin E succinate in human breast cancer cells.
    Zhao B; Yu W; Qian M; Simmons-Menchaca M; Brown P; Birrer MJ; Sanders BG; Kline K
    Mol Carcinog; 1997 Jul; 19(3):180-90. PubMed ID: 9254885
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of vinblastine-induced Bcl-xL and Bcl-2 phosphorylation: evidence for a novel protein kinase and a coordinated phosphorylation/dephosphorylation cycle associated with apoptosis induction.
    Du L; Lyle CS; Chambers TC
    Oncogene; 2005 Jan; 24(1):107-17. PubMed ID: 15531923
    [TBL] [Abstract][Full Text] [Related]  

  • 20. cFos is critical for MCF-7 breast cancer cell growth.
    Lu C; Shen Q; DuPré E; Kim H; Hilsenbeck S; Brown PH
    Oncogene; 2005 Sep; 24(43):6516-24. PubMed ID: 16027729
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.