BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

282 related articles for article (PubMed ID: 17131343)

  • 1. Pyrazolo-pyrimidine-derived c-Src inhibitor reduces angiogenesis and survival of squamous carcinoma cells by suppressing vascular endothelial growth factor production and signaling.
    Donnini S; Monti M; Castagnini C; Solito R; Botta M; Schenone S; Giachetti A; Ziche M
    Int J Cancer; 2007 Mar; 120(5):995-1004. PubMed ID: 17131343
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model.
    Trevino JG; Summy JM; Lesslie DP; Parikh NU; Hong DS; Lee FY; Donato NJ; Abbruzzese JL; Baker CH; Gallick GE
    Am J Pathol; 2006 Mar; 168(3):962-72. PubMed ID: 16507911
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CEP-7055: a novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models.
    Ruggeri B; Singh J; Gingrich D; Angeles T; Albom M; Yang S; Chang H; Robinson C; Hunter K; Dobrzanski P; Jones-Bolin S; Pritchard S; Aimone L; Klein-Szanto A; Herbert JM; Bono F; Schaeffer P; Casellas P; Bourie B; Pili R; Isaacs J; Ator M; Hudkins R; Vaught J; Mallamo J; Dionne C
    Cancer Res; 2003 Sep; 63(18):5978-91. PubMed ID: 14522925
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antiangiogenic mechanisms of PJ-8, a novel inhibitor of vascular endothelial growth factor receptor signaling.
    Huang SW; Lien JC; Kuo SC; Huang TF
    Carcinogenesis; 2012 May; 33(5):1022-30. PubMed ID: 22436611
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Both antiangiogenesis- and angiogenesis-independent effects are responsible for hepatocellular carcinoma growth arrest by tyrosine kinase inhibitor PTK787/ZK222584.
    Liu Y; Poon RT; Li Q; Kok TW; Lau C; Fan ST
    Cancer Res; 2005 May; 65(9):3691-9. PubMed ID: 15867364
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration.
    Wood JM; Bold G; Buchdunger E; Cozens R; Ferrari S; Frei J; Hofmann F; Mestan J; Mett H; O'Reilly T; Persohn E; Rösel J; Schnell C; Stover D; Theuer A; Towbin H; Wenger F; Woods-Cook K; Menrad A; Siemeister G; Schirner M; Thierauch KH; Schneider MR; Drevs J; Martiny-Baron G; Totzke F
    Cancer Res; 2000 Apr; 60(8):2178-89. PubMed ID: 10786682
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The farnesyltransferase inhibitor LB42708 suppresses vascular endothelial growth factor-induced angiogenesis by inhibiting ras-dependent mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signal pathways.
    Kim CK; Choi YK; Lee H; Ha KS; Won MH; Kwon YG; Kim YM
    Mol Pharmacol; 2010 Jul; 78(1):142-50. PubMed ID: 20406854
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Key enzymes of degradation and angiogenesis as a factors of tumor progression in squamous cell carcinoma of the cervix].
    Solov'eva NI; Timoshenko OS; Kugaevskaia EV; Andreeva IuIu; Zavalishina LE
    Bioorg Khim; 2014; 40(6):743-51. PubMed ID: 25895371
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel matrix metalloproteinase-2 inhibitor triazolylmethyl aziridine reduces melanoma cell invasion, angiogenesis and targets ERK1/2 phosphorylation.
    Romanchikova N; Trapencieris P; Zemītis J; Turks M
    J Enzyme Inhib Med Chem; 2014 Dec; 29(6):765-72. PubMed ID: 24246091
    [TBL] [Abstract][Full Text] [Related]  

  • 10. c-Src mediates mitogenic signals and associates with cytoskeletal proteins upon vascular endothelial growth factor stimulation in Kaposi's sarcoma cells.
    Munshi N; Groopman JE; Gill PS; Ganju RK
    J Immunol; 2000 Feb; 164(3):1169-74. PubMed ID: 10640727
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of Src kinase inhibition on metastasis and tumor angiogenesis in human pancreatic cancer.
    Ischenko I; Guba M; Yezhelyev M; Papyan A; Schmid G; Green T; Fennell M; Jauch KW; Bruns CJ
    Angiogenesis; 2007; 10(3):167-82. PubMed ID: 17486419
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Blocking angiogenesis and tumorigenesis with GFA-116, a synthetic molecule that inhibits binding of vascular endothelial growth factor to its receptor.
    Sun J; Blaskovich MA; Jain RK; Delarue F; Paris D; Brem S; Wotoczek-Obadia M; Lin Q; Coppola D; Choi K; Mullan M; Hamilton AD; Sebti SM
    Cancer Res; 2004 May; 64(10):3586-92. PubMed ID: 15150116
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HGF/NK4, a four-kringle antagonist of hepatocyte growth factor, is an angiogenesis inhibitor that suppresses tumor growth and metastasis in mice.
    Kuba K; Matsumoto K; Date K; Shimura H; Tanaka M; Nakamura T
    Cancer Res; 2000 Dec; 60(23):6737-43. PubMed ID: 11118060
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Visfatin induces human endothelial VEGF and MMP-2/9 production via MAPK and PI3K/Akt signalling pathways: novel insights into visfatin-induced angiogenesis.
    Adya R; Tan BK; Punn A; Chen J; Randeva HS
    Cardiovasc Res; 2008 May; 78(2):356-65. PubMed ID: 18093986
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Deciphering mechanisms controlling placental artery endothelial cell migration stimulated by vascular endothelial growth factor.
    Liao WX; Feng L; Zheng J; Chen DB
    Endocrinology; 2010 Jul; 151(7):3432-44. PubMed ID: 20463056
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Plasminogen activator inhibitor type-1 gene expression and induced migration in TGF-beta1-stimulated smooth muscle cells is pp60(c-src)/MEK-dependent.
    Samarakoon R; Higgins CE; Higgins SP; Kutz SM; Higgins PJ
    J Cell Physiol; 2005 Jul; 204(1):236-46. PubMed ID: 15622520
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MMP inhibition blocks fibroblast-dependent skin cancer invasion, reduces vascularization and alters VEGF-A and PDGF-BB expression.
    Woenne EC; Lederle W; Zwick S; Palmowski M; Krell H; Semmler W; Mueller MM; Kiessling F
    Anticancer Res; 2010 Mar; 30(3):703-11. PubMed ID: 20392987
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of cell growth and up-regulation of MAD2 in human oesophageal squamous cell carcinoma after treatment with the Src/Abl inhibitor dasatinib.
    Wang L; Guo B; Wang R; Jiang Y; Qin S; Liang S; Zhao Y; Guo W; Li K; Fan X
    Clin Sci (Lond); 2012 Jan; 122(1):13-24. PubMed ID: 21751967
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Endothelium-derived nitric oxide (NO) activates the NO-epidermal growth factor receptor-mediated signaling pathway in bradykinin-stimulated angiogenesis.
    Moraes MS; Costa PE; Batista WL; Paschoalin T; Curcio MF; Borges RE; Taha MO; Fonseca FV; Stern A; Monteiro HP
    Arch Biochem Biophys; 2014 Sep; 558():14-27. PubMed ID: 24960080
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Contribution of the Src family of kinases to the appearance of malignant phenotypes in renal cancer cells.
    Yonezawa Y; Nagashima Y; Sato H; Virgona N; Fukumoto K; Shirai S; Hagiwara H; Seki T; Ariga T; Senba H; Suzuki K; Asano R; Hagiwara K; Yano T
    Mol Carcinog; 2005 Aug; 43(4):188-97. PubMed ID: 15864803
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.