BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

312 related articles for article (PubMed ID: 17135187)

  • 1. Mutations in the MutSalpha interaction interface of MLH1 can abolish DNA mismatch repair.
    Plotz G; Welsch C; Giron-Monzon L; Friedhoff P; Albrecht M; Piiper A; Biondi RM; Lengauer T; Zeuzem S; Raedle J
    Nucleic Acids Res; 2006; 34(22):6574-86. PubMed ID: 17135187
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel interaction between human DNA polymerase eta and MutLalpha.
    Kanao R; Hanaoka F; Masutani C
    Biochem Biophys Res Commun; 2009 Nov; 389(1):40-5. PubMed ID: 19703417
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nuclear import of human MLH1, PMS2, and MutLalpha: redundancy is the key.
    Leong V; Lorenowicz J; Kozij N; Guarné A
    Mol Carcinog; 2009 Aug; 48(8):742-50. PubMed ID: 19148896
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The beta sliding clamp binds to multiple sites within MutL and MutS.
    López de Saro FJ; Marinus MG; Modrich P; O'Donnell M
    J Biol Chem; 2006 May; 281(20):14340-9. PubMed ID: 16546997
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Contribution of human mlh1 and pms2 ATPase activities to DNA mismatch repair.
    Tomer G; Buermeyer AB; Nguyen MM; Liskay RM
    J Biol Chem; 2002 Jun; 277(24):21801-9. PubMed ID: 11897781
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of Lynch syndrome mutations in the MLH1-PMS2 interface that disturb dimerization and mismatch repair.
    Kosinski J; Hinrichsen I; Bujnicki JM; Friedhoff P; Plotz G
    Hum Mutat; 2010 Aug; 31(8):975-82. PubMed ID: 20533529
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse.
    Chen PC; Dudley S; Hagen W; Dizon D; Paxton L; Reichow D; Yoon SR; Yang K; Arnheim N; Liskay RM; Lipkin SM
    Cancer Res; 2005 Oct; 65(19):8662-70. PubMed ID: 16204034
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Conservation of functional asymmetry in the mammalian MutLα ATPase.
    Johnson JR; Erdeniz N; Nguyen M; Dudley S; Liskay RM
    DNA Repair (Amst); 2010 Nov; 9(11):1209-13. PubMed ID: 20864418
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Truncation of the C-terminus of human MLH1 blocks intracellular stabilization of PMS2 and disrupts DNA mismatch repair.
    Mohd AB; Palama B; Nelson SE; Tomer G; Nguyen M; Huo X; Buermeyer AB
    DNA Repair (Amst); 2006 Mar; 5(3):347-61. PubMed ID: 16338176
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human mismatch-repair protein MutL homologue 1 (MLH1) interacts with Escherichia coli MutL and MutS in vivo and in vitro: a simple genetic system to assay MLH1 function.
    Quaresima B; Alifano P; Tassone P; Avvedimento EV; Costanzo FS; Venuta S
    Biochem J; 2003 Apr; 371(Pt 1):183-9. PubMed ID: 12513688
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Apoptosis and mutation in the murine small intestine: loss of Mlh1- and Pms2-dependent apoptosis leads to increased mutation in vivo.
    Sansom OJ; Bishop SM; Court H; Dudley S; Liskay RM; Clarke AR
    DNA Repair (Amst); 2003 Sep; 2(9):1029-39. PubMed ID: 12967659
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dimerization of MLH1 and PMS2 limits nuclear localization of MutLalpha.
    Wu X; Platt JL; Cascalho M
    Mol Cell Biol; 2003 May; 23(9):3320-8. PubMed ID: 12697830
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tumor mismatch repair immunohistochemistry and DNA MLH1 methylation testing of patients with endometrial cancer diagnosed at age younger than 60 years optimizes triage for population-level germline mismatch repair gene mutation testing.
    Buchanan DD; Tan YY; Walsh MD; Clendenning M; Metcalf AM; Ferguson K; Arnold ST; Thompson BA; Lose FA; Parsons MT; Walters RJ; Pearson SA; Cummings M; Oehler MK; Blomfield PB; Quinn MA; Kirk JA; Stewart CJ; Obermair A; Young JP; Webb PM; Spurdle AB
    J Clin Oncol; 2014 Jan; 32(2):90-100. PubMed ID: 24323032
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway.
    Liu Y; Fang Y; Shao H; Lindsey-Boltz L; Sancar A; Modrich P
    J Biol Chem; 2010 Feb; 285(8):5974-82. PubMed ID: 20029092
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MutLα heterodimers modify the molecular phenotype of Friedreich ataxia.
    Ezzatizadeh V; Sandi C; Sandi M; Anjomani-Virmouni S; Al-Mahdawi S; Pook MA
    PLoS One; 2014; 9(6):e100523. PubMed ID: 24971578
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mismatch repair pathway: molecules, functions, and role in colorectal carcinogenesis.
    Sameer AS; Nissar S; Fatima K
    Eur J Cancer Prev; 2014 Jul; 23(4):246-57. PubMed ID: 24614649
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dynamic human MutSα-MutLα complexes compact mismatched DNA.
    Bradford KC; Wilkins H; Hao P; Li ZM; Wang B; Burke D; Wu D; Smith AE; Spaller L; Du C; Gauer JW; Chan E; Hsieh P; Weninger KR; Erie DA
    Proc Natl Acad Sci U S A; 2020 Jul; 117(28):16302-16312. PubMed ID: 32586954
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SMARCAD1-mediated recruitment of the DNA mismatch repair protein MutLα to MutSα on damaged chromatin induces apoptosis in human cells.
    Takeishi Y; Fujikane R; Rikitake M; Obayashi Y; Sekiguchi M; Hidaka M
    J Biol Chem; 2020 Jan; 295(4):1056-1065. PubMed ID: 31843968
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Improved survival with an intact DNA mismatch repair system in endometrial cancer.
    Cohn DE; Frankel WL; Resnick KE; Zanagnolo VL; Copeland LJ; Hampel H; Kelbick N; Morrison CD; Fowler JM
    Obstet Gynecol; 2006 Nov; 108(5):1208-15. PubMed ID: 17077244
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mapping the dimer interface in the C-terminal domains of the yeast MLH1-PMS1 heterodimer.
    Cutalo JM; Darden TA; Kunkel TA; Tomer KB
    Biochemistry; 2006 Dec; 45(51):15458-67. PubMed ID: 17176067
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.