433 related articles for article (PubMed ID: 17137735)
1. Comparison of cytochrome P450 inhibition assays for drug discovery using human liver microsomes with LC-MS, rhCYP450 isozymes with fluorescence, and double cocktail with LC-MS.
Di L; Kerns EH; Li SQ; Carter GT
Int J Pharm; 2007 Apr; 335(1-2):1-11. PubMed ID: 17137735
[TBL] [Abstract][Full Text] [Related]
2. An automated, high-throughput, 384 well Cytochrome P450 cocktail IC50 assay using a rapid resolution LC-MS/MS end-point.
Youdim KA; Lyons R; Payne L; Jones BC; Saunders K
J Pharm Biomed Anal; 2008 Sep; 48(1):92-9. PubMed ID: 18584988
[TBL] [Abstract][Full Text] [Related]
3. Development and full validation of six inhibition assays for five major cytochrome P450 enzymes in human liver microsomes using an automated 96-well microplate incubation format and LC-MS/MS analysis.
Yao M; Zhu M; Sinz MW; Zhang H; Humphreys WG; Rodrigues AD; Dai R
J Pharm Biomed Anal; 2007 May; 44(1):211-23. PubMed ID: 17418993
[TBL] [Abstract][Full Text] [Related]
4. High-throughput cytochrome P450 (CYP) inhibition screening via a cassette probe-dosing strategy. VI. Simultaneous evaluation of inhibition potential of drugs on human hepatic isozymes CYP2A6, 3A4, 2C9, 2D6 and 2E1.
Bu HZ; Magis L; Knuth K; Teitelbaum P
Rapid Commun Mass Spectrom; 2001; 15(10):741-8. PubMed ID: 11344532
[TBL] [Abstract][Full Text] [Related]
5. A sensitive and high-throughput LC-MS/MS method for inhibition assay of seven major cytochrome P450s in human liver microsomes using an in vitro cocktail of probe substrates.
Liu LY; Han YL; Zhu JH; Yu Q; Yang QJ; Lu J; Guo C
Biomed Chromatogr; 2015 Mar; 29(3):437-44. PubMed ID: 25098274
[TBL] [Abstract][Full Text] [Related]
6. An in vitro, high throughput, seven CYP cocktail inhibition assay for the evaluation of new chemical entities using LC-MS/MS.
Otten JN; Hingorani GP; Hartley DP; Kragerud SD; Franklin RB
Drug Metab Lett; 2011 Jan; 5(1):17-24. PubMed ID: 21198441
[TBL] [Abstract][Full Text] [Related]
7. Evaluation of cytochrome P450 inhibition assays using human liver microsomes by a cassette analysis /LC-MS/MS.
Zambon S; Fontana S; Kajbaf M
Drug Metab Lett; 2010 Aug; 4(3):120-8. PubMed ID: 20642444
[TBL] [Abstract][Full Text] [Related]
8. Reliable high-throughput method for inhibition assay of 8 cytochrome P450 isoforms using cocktail of probe substrates and stable isotope-labeled internal standards.
Kozakai K; Yamada Y; Oshikata M; Kawase T; Suzuki E; Haramaki Y; Taniguchi H
Drug Metab Pharmacokinet; 2012; 27(5):520-9. PubMed ID: 22498647
[TBL] [Abstract][Full Text] [Related]
9. Investigation of the inhibition of eight major human cytochrome P450 isozymes by a probe substrate cocktail
Valicherla GR; Mishra A; Lenkalapelly S; Jillela B; Francis FM; Rajagopalan L; Srivastava P
Xenobiotica; 2019 Dec; 49(12):1396-1402. PubMed ID: 30747554
[TBL] [Abstract][Full Text] [Related]
10. Simultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5'-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography-Tandem Mass Spectrometry.
Lee B; Ji HK; Lee T; Liu KH
Drug Metab Dispos; 2015 Jul; 43(7):1137-46. PubMed ID: 25904760
[TBL] [Abstract][Full Text] [Related]
11. Screening of ten cytochrome P450 enzyme activities with 12 probe substrates in human liver microsomes using cocktail incubation and liquid chromatography-tandem mass spectrometry.
Kim HJ; Lee H; Ji HK; Lee T; Liu KH
Biopharm Drug Dispos; 2019 Apr; 40(3-4):101-111. PubMed ID: 30730576
[TBL] [Abstract][Full Text] [Related]
12. Development of an in vitro drug-drug interaction assay to simultaneously monitor five cytochrome P450 isoforms and performance assessment using drug library compounds.
Zientek M; Miller H; Smith D; Dunklee MB; Heinle L; Thurston A; Lee C; Hyland R; Fahmi O; Burdette D
J Pharmacol Toxicol Methods; 2008; 58(3):206-14. PubMed ID: 18634893
[TBL] [Abstract][Full Text] [Related]
13. Validation of higher-throughput high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry assays to conduct cytochrome P450s CYP2D6 and CYP3A4 enzyme inhibition studies in human liver microsomes.
Chu I; Favreau L; Soares T; Lin Cc; Nomeir AA
Rapid Commun Mass Spectrom; 2000; 14(4):207-14. PubMed ID: 10669878
[TBL] [Abstract][Full Text] [Related]
14. In vitro assessment of cytochrome P450 inhibition: strategies for increasing LC/MS-based assay throughput using a one-point IC(50) method and multiplexing high-performance liquid chromatography.
Lin T; Pan K; Mordenti J; Pan L
J Pharm Sci; 2007 Sep; 96(9):2485-93. PubMed ID: 17542019
[TBL] [Abstract][Full Text] [Related]
15. Competition between cytochrome P-450 isozymes for NADPH-cytochrome P-450 oxidoreductase affects drug metabolism.
Li DN; Pritchard MP; Hanlon SP; Burchell B; Wolf CR; Friedberg T
J Pharmacol Exp Ther; 1999 May; 289(2):661-7. PubMed ID: 10215637
[TBL] [Abstract][Full Text] [Related]
16. Potent inhibition of cytochrome P450 2B6 by sibutramine in human liver microsomes.
Bae SH; Kwon MJ; Choi EJ; Zheng YF; Yoon KD; Liu KH; Bae SK
Chem Biol Interact; 2013 Sep; 205(1):11-9. PubMed ID: 23777987
[TBL] [Abstract][Full Text] [Related]
17. Rapid screening of commercially available herbal products for the inhibition of major human hepatic cytochrome P450 enzymes using the N-in-one cocktail.
Sevior DK; Hokkanen J; Tolonen A; Abass K; Tursas L; Pelkonen O; Ahokas JT
Xenobiotica; 2010 Apr; 40(4):245-54. PubMed ID: 20218935
[TBL] [Abstract][Full Text] [Related]
18. Optimizing higher throughput methods to assess drug-drug interactions for CYP1A2, CYP2C9, CYP2C19, CYP2D6, rCYP2D6, and CYP3A4 in vitro using a single point IC(50).
Gao F; Johnson DL; Ekins S; Janiszewski J; Kelly KG; Meyer RD; West M
J Biomol Screen; 2002 Aug; 7(4):373-82. PubMed ID: 12230892
[TBL] [Abstract][Full Text] [Related]
19. A comprehensive assay for nine major cytochrome P450 enzymes activities with 16 probe reactions on human liver microsomes by a single LC/MS/MS run to support reliable in vitro inhibitory drug-drug interaction evaluation.
Peng Y; Wu H; Zhang X; Zhang F; Qi H; Zhong Y; Wang Y; Sang H; Wang G; Sun J
Xenobiotica; 2015; 45(11):961-77. PubMed ID: 26007223
[TBL] [Abstract][Full Text] [Related]
20. Development of an in vitro cytochrome P450 cocktail inhibition assay for assessing the inhibition risk of drugs of abuse.
Dinger J; Meyer MR; Maurer HH
Toxicol Lett; 2014 Oct; 230(1):28-35. PubMed ID: 25111188
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]