BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

225 related articles for article (PubMed ID: 17141805)

  • 1. Analysis of amino acids in the beta7-beta8 loop of human immunodeficiency virus type 1 reverse transcriptase for their role in virus replication.
    Mulky A; Vu BC; Conway JA; Hughes SH; Kappes JC
    J Mol Biol; 2007 Feb; 365(5):1368-78. PubMed ID: 17141805
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The N137 and P140 amino acids in the p51 and the P95 amino acid in the p66 subunit of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase are instrumental to maintain catalytic activity and to design new classes of anti-HIV-1 drugs.
    Auwerx J; Van Nieuwenhove J; Rodríguez-Barrios F; de Castro S; Velázquez S; Ceccherini-Silberstein F; De Clercq E; Camarasa MJ; Perno CF; Gago F; Balzarini J
    FEBS Lett; 2005 Apr; 579(11):2294-300. PubMed ID: 15848161
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of amino acid residues in the human immunodeficiency virus type-1 reverse transcriptase tryptophan-repeat motif that are required for subunit interaction using infectious virions.
    Mulky A; Sarafianos SG; Jia Y; Arnold E; Kappes JC
    J Mol Biol; 2005 Jun; 349(4):673-84. PubMed ID: 15893326
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The amino acid Asn136 in HIV-1 reverse transcriptase (RT) maintains efficient association of both RT subunits and enables the rational design of novel RT inhibitors.
    Balzarini J; Auwerx J; Rodríguez-Barrios F; Chedad A; Farkas V; Ceccherini-Silberstein F; García-Aparicio C; Velázquez S; De Clercq E; Perno CF; Camarasa MJ; Gago F
    Mol Pharmacol; 2005 Jul; 68(1):49-60. PubMed ID: 15833734
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A single deletion at position 134, 135, or 136 in the beta 7-beta 8 loop of the p51 subunit of HIV-1 RT disrupts the formation of heterodimeric enzyme.
    Upadhyay A; Pandey N; Mishra CA; Talele TT; Pandey VN
    J Cell Biochem; 2010 Feb; 109(3):598-605. PubMed ID: 20013797
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The beta7-beta8 loop of the p51 subunit in the heterodimeric (p66/p51) human immunodeficiency virus type 1 reverse transcriptase is essential for the catalytic function of the p66 subunit.
    Pandey PK; Kaushik N; Talele TT; Yadav PN; Pandey VN
    Biochemistry; 2001 Aug; 40(32):9505-12. PubMed ID: 11583149
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Glutamic residue 438 within the protease-sensitive subdomain of HIV-1 reverse transcriptase is critical for heterodimer processing in viral particles.
    Navarro JM; Damier L; Boretto J; Priet S; Canard B; Quérat G; Sire J
    Virology; 2001 Nov; 290(2):300-8. PubMed ID: 11883194
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insertion of a small peptide of six amino acids into the beta7-beta8 loop of the p51 subunit of HIV-1 reverse transcriptase perturbs the heterodimer and affects its activities.
    Pandey PK; Kaushik N; Singh K; Sharma B; Upadhyay AK; Kumar S; Harris D; Pandey VN
    BMC Biochem; 2002 Jun; 3():18. PubMed ID: 12086585
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Subunit-specific analysis of the human immunodeficiency virus type 1 reverse transcriptase in vivo.
    Mulky A; Sarafianos SG; Arnold E; Wu X; Kappes JC
    J Virol; 2004 Jul; 78(13):7089-96. PubMed ID: 15194785
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HIV-1 protease dimer interface mutations that compensate for viral reverse transcriptase instability in infectious virions.
    Olivares I; Mulky A; Boross PI; Tözsér J; Kappes JC; López-Galíndez C; Menéndez-Arias L
    J Mol Biol; 2007 Sep; 372(2):369-81. PubMed ID: 17651754
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Virion instability of human immunodeficiency virus type 1 reverse transcriptase (RT) mutated in the protease cleavage site between RT p51 and the RT RNase H domain.
    Abram ME; Parniak MA
    J Virol; 2005 Sep; 79(18):11952-61. PubMed ID: 16140771
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The nature of the N-terminal amino acid residue of HIV-1 RNase H is critical for the stability of reverse transcriptase in viral particles.
    Boso G; Örvell C; Somia NV
    J Virol; 2015 Jan; 89(2):1286-97. PubMed ID: 25392207
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutations that abrogate human immunodeficiency virus type 1 reverse transcriptase dimerization affect maturation of the reverse transcriptase heterodimer.
    Wapling J; Moore KL; Sonza S; Mak J; Tachedjian G
    J Virol; 2005 Aug; 79(16):10247-57. PubMed ID: 16051818
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vitro characterization of a simian immunodeficiency virus-human immunodeficiency virus (HIV) chimera expressing HIV type 1 reverse transcriptase to study antiviral resistance in pigtail macaques.
    Ambrose Z; Boltz V; Palmer S; Coffin JM; Hughes SH; Kewalramani VN
    J Virol; 2004 Dec; 78(24):13553-61. PubMed ID: 15564466
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT.
    Nissley DV; Radzio J; Ambrose Z; Sheen CW; Hamamouch N; Moore KL; Tachedjian G; Sluis-Cremer N
    Biochem J; 2007 May; 404(1):151-7. PubMed ID: 17286555
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The p51 subunit of human immunodeficiency virus type 1 reverse transcriptase is essential in loading the p66 subunit on the template primer.
    Harris D; Lee R; Misra HS; Pandey PK; Pandey VN
    Biochemistry; 1998 Apr; 37(17):5903-8. PubMed ID: 9558323
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analysis of human immunodeficiency virus type 1 reverse transcriptase subunit structure/function in the context of infectious virions and human target cells.
    Mulky A; Kappes JC
    Antimicrob Agents Chemother; 2005 Sep; 49(9):3762-9. PubMed ID: 16127051
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Proteolytic processing of an HIV-1 pol polyprotein precursor: insights into the mechanism of reverse transcriptase p66/p51 heterodimer formation.
    Sluis-Cremer N; Arion D; Abram ME; Parniak MA
    Int J Biochem Cell Biol; 2004 Sep; 36(9):1836-47. PubMed ID: 15183348
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human immunodeficiency virus type 1 reverse transcriptase dimer destabilization by 1-[Spiro[4"-amino-2",2" -dioxo-1",2" -oxathiole-5",3'-[2', 5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]]]-3-ethylthy mine.
    Sluis-Cremer N; Dmitrienko GI; Balzarini J; Camarasa MJ; Parniak MA
    Biochemistry; 2000 Feb; 39(6):1427-33. PubMed ID: 10684624
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nonnucleoside reverse transcriptase inhibitors are chemical enhancers of dimerization of the HIV type 1 reverse transcriptase.
    Tachedjian G; Orlova M; Sarafianos SG; Arnold E; Goff SP
    Proc Natl Acad Sci U S A; 2001 Jun; 98(13):7188-93. PubMed ID: 11416202
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.