BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

264 related articles for article (PubMed ID: 17146286)

  • 1. Motor neuron disease in mice expressing the wild type-like D90A mutant superoxide dismutase-1.
    Jonsson PA; Graffmo KS; Brännström T; Nilsson P; Andersen PM; Marklund SL
    J Neuropathol Exp Neurol; 2006 Dec; 65(12):1126-36. PubMed ID: 17146286
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modulation of mutant superoxide dismutase 1 aggregation by co-expression of wild-type enzyme.
    Prudencio M; Durazo A; Whitelegge JP; Borchelt DR
    J Neurochem; 2009 Feb; 108(4):1009-18. PubMed ID: 19077113
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
    Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
    Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Disulphide-reduced superoxide dismutase-1 in CNS of transgenic amyotrophic lateral sclerosis models.
    Jonsson PA; Graffmo KS; Andersen PM; Brännström T; Lindberg M; Oliveberg M; Marklund SL
    Brain; 2006 Feb; 129(Pt 2):451-64. PubMed ID: 16330499
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis.
    Turner BJ; Atkin JD; Farg MA; Zang DW; Rembach A; Lopes EC; Patch JD; Hill AF; Cheema SS
    J Neurosci; 2005 Jan; 25(1):108-17. PubMed ID: 15634772
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Overloading of stable and exclusion of unstable human superoxide dismutase-1 variants in mitochondria of murine amyotrophic lateral sclerosis models.
    Bergemalm D; Jonsson PA; Graffmo KS; Andersen PM; Brännström T; Rehnmark A; Marklund SL
    J Neurosci; 2006 Apr; 26(16):4147-54. PubMed ID: 16624935
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Toll-Like Receptor-4 Inhibitor TAK-242 Attenuates Motor Dysfunction and Spinal Cord Pathology in an Amyotrophic Lateral Sclerosis Mouse Model.
    Fellner A; Barhum Y; Angel A; Perets N; Steiner I; Offen D; Lev N
    Int J Mol Sci; 2017 Aug; 18(8):. PubMed ID: 28763002
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant superoxide dismutase aggregates from human spinal cord transmit amyotrophic lateral sclerosis.
    Ekhtiari Bidhendi E; Bergh J; Zetterström P; Forsberg K; Pakkenberg B; Andersen PM; Marklund SL; Brännström T
    Acta Neuropathol; 2018 Dec; 136(6):939-953. PubMed ID: 30284034
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA.
    Wang J; Xu G; Slunt HH; Gonzales V; Coonfield M; Fromholt D; Copeland NG; Jenkins NA; Borchelt DR
    Neurobiol Dis; 2005 Dec; 20(3):943-52. PubMed ID: 16046140
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nuclear localization of human SOD1 and mutant SOD1-specific disruption of survival motor neuron protein complex in transgenic amyotrophic lateral sclerosis mice.
    Gertz B; Wong M; Martin LJ
    J Neuropathol Exp Neurol; 2012 Feb; 71(2):162-77. PubMed ID: 22249462
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Decreased glutathione levels cause overt motor neuron degeneration in hSOD1
    Killoy KM; Harlan BA; Pehar M; Helke KL; Johnson JA; Vargas MR
    Exp Neurol; 2018 Apr; 302():129-135. PubMed ID: 29307609
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vivo quantification of spinal and bulbar motor neuron degeneration in the G93A-SOD1 transgenic mouse model of ALS by T2 relaxation time and apparent diffusion coefficient.
    Niessen HG; Angenstein F; Sander K; Kunz WS; Teuchert M; Ludolph AC; Heinze HJ; Scheich H; Vielhaber S
    Exp Neurol; 2006 Oct; 201(2):293-300. PubMed ID: 16740261
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transient recovery in a rat model of familial amyotrophic lateral sclerosis after transplantation of motor neurons derived from mouse embryonic stem cells.
    López-González R; Kunckles P; Velasco I
    Cell Transplant; 2009; 18(10):1171-81. PubMed ID: 19660174
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues.
    Watanabe M; Dykes-Hoberg M; Culotta VC; Price DL; Wong PC; Rothstein JD
    Neurobiol Dis; 2001 Dec; 8(6):933-41. PubMed ID: 11741389
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1.
    Bruijn LI; Houseweart MK; Kato S; Anderson KL; Anderson SD; Ohama E; Reaume AG; Scott RW; Cleveland DW
    Science; 1998 Sep; 281(5384):1851-4. PubMed ID: 9743498
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transcriptional profiling in the lumbar spinal cord of a mouse model of amyotrophic lateral sclerosis: a role for wild-type superoxide dismutase 1 in sporadic disease?
    D'Arrigo A; Colavito D; Peña-Altamira E; Fabris M; Dam M; Contestabile A; Leon A
    J Mol Neurosci; 2010 Jul; 41(3):404-15. PubMed ID: 20177826
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Preserved slow conducting corticomotoneuronal projections in amyotrophic lateral sclerosis with autosomal recessive D90A CuZn-superoxide dismutase mutation.
    Weber M; Eisen A; Stewart HG; Andersen PM
    Brain; 2000 Jul; 123 ( Pt 7)():1505-15. PubMed ID: 10869061
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neuroprotective effect of oxidized galectin-1 in a transgenic mouse model of amyotrophic lateral sclerosis.
    Chang-Hong R; Wada M; Koyama S; Kimura H; Arawaka S; Kawanami T; Kurita K; Kadoya T; Aoki M; Itoyama Y; Kato T
    Exp Neurol; 2005 Jul; 194(1):203-11. PubMed ID: 15899257
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis.
    Jonsson PA; Ernhill K; Andersen PM; Bergemalm D; Brännström T; Gredal O; Nilsson P; Marklund SL
    Brain; 2004 Jan; 127(Pt 1):73-88. PubMed ID: 14534160
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Determinants of rapid disease progression in ALS.
    Yamanaka K; Cleveland DW
    Neurology; 2005 Dec; 65(12):1859-60. PubMed ID: 16380607
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 14.