These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

324 related articles for article (PubMed ID: 17148679)

  • 1. Activation of mammalian target of rapamycin signaling promotes cell cycle progression and protects cells from apoptosis in mantle cell lymphoma.
    Peponi E; Drakos E; Reyes G; Leventaki V; Rassidakis GZ; Medeiros LJ
    Am J Pathol; 2006 Dec; 169(6):2171-80. PubMed ID: 17148679
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Overexpressed eIF4E is functionally active in surgical margins of head and neck cancer patients via activation of the Akt/mammalian target of rapamycin pathway.
    Nathan CO; Amirghahari N; Abreo F; Rong X; Caldito G; Jones ML; Zhou H; Smith M; Kimberly D; Glass J
    Clin Cancer Res; 2004 Sep; 10(17):5820-7. PubMed ID: 15355912
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity.
    deGraffenried LA; Friedrichs WE; Russell DH; Donzis EJ; Middleton AK; Silva JM; Roth RA; Hidalgo M
    Clin Cancer Res; 2004 Dec; 10(23):8059-67. PubMed ID: 15585641
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers.
    Zhou X; Tan M; Stone Hawthorne V; Klos KS; Lan KH; Yang Y; Yang W; Smith TL; Shi D; Yu D
    Clin Cancer Res; 2004 Oct; 10(20):6779-88. PubMed ID: 15501954
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The rapamycin-sensitive signal transduction pathway as a target for cancer therapy.
    Hidalgo M; Rowinsky EK
    Oncogene; 2000 Dec; 19(56):6680-6. PubMed ID: 11426655
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of phospholipase D1 in the regulation of mTOR activity by lysophosphatidic acid.
    Kam Y; Exton JH
    FASEB J; 2004 Feb; 18(2):311-9. PubMed ID: 14769825
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of phosphatidylinositol 3-kinase- and ERK MAPK-regulated protein synthesis reveals the pro-apoptotic properties of CD40 ligation in carcinoma cells.
    Davies CC; Mason J; Wakelam MJ; Young LS; Eliopoulos AG
    J Biol Chem; 2004 Jan; 279(2):1010-9. PubMed ID: 14581487
    [TBL] [Abstract][Full Text] [Related]  

  • 8. p53 activation results in rapid dephosphorylation of the eIF4E-binding protein 4E-BP1, inhibition of ribosomal protein S6 kinase and inhibition of translation initiation.
    Horton LE; Bushell M; Barth-Baus D; Tilleray VJ; Clemens MJ; Hensold JO
    Oncogene; 2002 Aug; 21(34):5325-34. PubMed ID: 12149653
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Constitutive activation of phosphatidyl-inositide 3 kinase contributes to the survival of Hodgkin's lymphoma cells through a mechanism involving Akt kinase and mTOR.
    Dutton A; Reynolds GM; Dawson CW; Young LS; Murray PG
    J Pathol; 2005 Mar; 205(4):498-506. PubMed ID: 15714459
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition.
    Sun SY; Rosenberg LM; Wang X; Zhou Z; Yue P; Fu H; Khuri FR
    Cancer Res; 2005 Aug; 65(16):7052-8. PubMed ID: 16103051
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Determinants of rapamycin sensitivity in breast cancer cells.
    Noh WC; Mondesire WH; Peng J; Jian W; Zhang H; Dong J; Mills GB; Hung MC; Meric-Bernstam F
    Clin Cancer Res; 2004 Feb; 10(3):1013-23. PubMed ID: 14871980
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of phosphatidylinositol 3-kinase, Akt, and mammalian target of rapamycin is necessary for hypoxia-induced pulmonary artery adventitial fibroblast proliferation.
    Gerasimovskaya EV; Tucker DA; Stenmark KR
    J Appl Physiol (1985); 2005 Feb; 98(2):722-31. PubMed ID: 15501927
    [TBL] [Abstract][Full Text] [Related]  

  • 13. FRAP-p70s6K signaling is required for pancreatic cancer cell proliferation.
    Shah SA; Potter MW; Ricciardi R; Perugini RA; Callery MP
    J Surg Res; 2001 May; 97(2):123-30. PubMed ID: 11341787
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma.
    Pene F; Claessens YE; Muller O; ViguiƩ F; Mayeux P; Dreyfus F; Lacombe C; Bouscary D
    Oncogene; 2002 Sep; 21(43):6587-97. PubMed ID: 12242656
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function.
    Schalm SS; Fingar DC; Sabatini DM; Blenis J
    Curr Biol; 2003 May; 13(10):797-806. PubMed ID: 12747827
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of the p70 S6 kinase and phosphorylation of the 4E-BP1 repressor of mRNA translation by type I interferons.
    Lekmine F; Uddin S; Sassano A; Parmar S; Brachmann SM; Majchrzak B; Sonenberg N; Hay N; Fish EN; Platanias LC
    J Biol Chem; 2003 Jul; 278(30):27772-80. PubMed ID: 12759354
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tumstatin, an endothelial cell-specific inhibitor of protein synthesis.
    Maeshima Y; Sudhakar A; Lively JC; Ueki K; Kharbanda S; Kahn CR; Sonenberg N; Hynes RO; Kalluri R
    Science; 2002 Jan; 295(5552):140-3. PubMed ID: 11778052
    [TBL] [Abstract][Full Text] [Related]  

  • 18. S6K1 and 4E-BP1 are independent regulated and control cellular growth in bladder cancer.
    Nawroth R; Stellwagen F; Schulz WA; Stoehr R; Hartmann A; Krause BJ; Gschwend JE; Retz M
    PLoS One; 2011; 6(11):e27509. PubMed ID: 22110663
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacogenomic profiling of the PI3K/PTEN-AKT-mTOR pathway in common human tumors.
    Xu G; Zhang W; Bertram P; Zheng XF; McLeod H
    Int J Oncol; 2004 Apr; 24(4):893-900. PubMed ID: 15010827
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E.
    Fingar DC; Salama S; Tsou C; Harlow E; Blenis J
    Genes Dev; 2002 Jun; 16(12):1472-87. PubMed ID: 12080086
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.