BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 17150635)

  • 1. X-ray analyses of hybrid duplexes between antisense oligonucleotides containing 5-(N-aminohexyl)carbamoyl-2'-O-methyluridine and their target RNAs.
    Juan EC; Kondo J; Ito T; Ueno Y; Matsuda A; Takénaka A
    Nucleic Acids Symp Ser (Oxf); 2005; (49):65-6. PubMed ID: 17150635
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structures of DNA:DNA and DNA:RNA duplexes containing 5-(N-aminohexyl)carbamoyl-modified uracils reveal the basis for properties as antigene and antisense molecules.
    Juan EC; Kondo J; Kurihara T; Ito T; Ueno Y; Matsuda A; Takénaka A
    Nucleic Acids Res; 2007; 35(6):1969-77. PubMed ID: 17341465
    [TBL] [Abstract][Full Text] [Related]  

  • 3. X-ray analyses of DNA duplexes containing 5-(N-aminohexyl)carbamoyl modifications.
    Juan EC; Kurihara T; Kondo J; Ito T; Ueno Y; Matsuda A; Takénaka A
    Nucleic Acids Symp Ser (Oxf); 2004; (48):305-6. PubMed ID: 17150600
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Conformation of formacetal and 3'-thioformacetal nucleotide linkers and stability of their antisense RNA.DNA hybrid duplexes.
    Rice JS; Gao X
    Biochemistry; 1997 Jan; 36(2):399-411. PubMed ID: 9003193
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogues.
    Pattanayek R; Sethaphong L; Pan C; Prhavc M; Prakash TP; Manoharan M; Egli M
    J Am Chem Soc; 2004 Nov; 126(46):15006-7. PubMed ID: 15547979
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparison of the RNase H cleavage kinetics and blood serum stability of the north-conformationally constrained and 2'-alkoxy modified oligonucleotides.
    Honcharenko D; Barman J; Varghese OP; Chattopadhyaya J
    Biochemistry; 2007 May; 46(19):5635-46. PubMed ID: 17411072
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fine tuning of electrostatics around the internucleotidic phosphate through incorporation of modified 2',4'-carbocyclic-LNAs and -ENAs leads to significant modulation of antisense properties.
    Zhou C; Liu Y; Andaloussi M; Badgujar N; Plashkevych O; Chattopadhyaya J
    J Org Chem; 2009 Jan; 74(1):118-34. PubMed ID: 19055352
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Duplex recognition by oligonucleotides containing 2'-deoxy-2'-fluoro-D-arabinose and 2'-deoxy-2'-fluoro-D-ribose. Intermolecular 2'-OH-phosphate contacts versus sugar puckering in the stabilization of triple-helical complexes.
    Wilds CJ; Damha MJ
    Bioconjug Chem; 1999; 10(2):299-305. PubMed ID: 10077480
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Correlating structure and stability of DNA duplexes with incorporated 2'-O-modified RNA analogues.
    Tereshko V; Portmann S; Tay EC; Martin P; Natt F; Altmann KH; Egli M
    Biochemistry; 1998 Jul; 37(30):10626-34. PubMed ID: 9692952
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and hybridization of 2'-O-methyl-RNAs incorporating 2'-O-carbamoyluridine and unique participation of the carbamoyl group in U-G base pair.
    Seio K; Tawarada R; Sasami T; Serizawa M; Ise M; Ohkubo A; Sekine M
    Bioorg Med Chem; 2009 Oct; 17(20):7275-80. PubMed ID: 19783446
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structure of an RNA duplex r(gugucgcac)(2) with uridine bulges.
    Xiong Y; Deng J; Sudarsanakumar C; Sundaralingam M
    J Mol Biol; 2001 Oct; 313(3):573-82. PubMed ID: 11676540
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 2'-O-[2-(methylthio)ethyl]-modified oligonucleotide: an analogue of 2'-O-[2-(methoxy)-ethyl]-modified oligonucleotide with improved protein binding properties and high binding affinity to target RNA.
    Prakash TP; Manoharan M; Kawasaki AM; Fraser AS; Lesnik EA; Sioufi N; Leeds JM; Teplova M; Egli M
    Biochemistry; 2002 Oct; 41(39):11642-8. PubMed ID: 12269806
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2'-O-ribonucleic acid modifications.
    Egli M; Minasov G; Tereshko V; Pallan PS; Teplova M; Inamati GB; Lesnik EA; Owens SR; Ross BS; Prakash TP; Manoharan M
    Biochemistry; 2005 Jun; 44(25):9045-57. PubMed ID: 15966728
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Solution structure of an RNA.2'-O-methylated RNA hybrid duplex containing an RNA.DNA hybrid segment at the center.
    Nishizaki T; Iwai S; Ohtsuka E; Nakamura H
    Biochemistry; 1997 Mar; 36(9):2577-85. PubMed ID: 9054564
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, thermal stability and resistance to enzymatic hydrolysis of the oligonucleotides containing 5-(N-aminohexyl)carbamoyl-2'-O-methyluridines.
    Ito T; Ueno Y; Komatsu Y; Matsuda A
    Nucleic Acids Res; 2003 May; 31(10):2514-23. PubMed ID: 12736300
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and properties of cationic 2'-O-[N-(4-aminobutyl)carbamoyl] modified oligonucleotides.
    Seio K; Tokugawa M; Kanamori T; Tsunoda H; Ohkubo A; Sekine M
    Bioorg Med Chem Lett; 2012 Apr; 22(7):2470-3. PubMed ID: 22406150
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interplay of LNA and 2'-O-methyl RNA in the structure and thermodynamics of RNA hybrid systems: a molecular dynamics study using the revised AMBER force field and comparison with experimental results.
    Yildirim I; Kierzek E; Kierzek R; Schatz GC
    J Phys Chem B; 2014 Dec; 118(49):14177-87. PubMed ID: 25268896
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inclusion of methoxy groups inverts the thermodynamic stabilities of DNA-RNA hybrid duplexes: A molecular dynamics simulation study.
    Suresh G; Priyakumar UD
    J Mol Graph Model; 2015 Sep; 61():150-9. PubMed ID: 26254870
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structure and improved antisense properties of 2'-O-(2-methoxyethyl)-RNA.
    Teplova M; Minasov G; Tereshko V; Inamati GB; Cook PD; Manoharan M; Egli M
    Nat Struct Biol; 1999 Jun; 6(6):535-9. PubMed ID: 10360355
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and properties of 2'-O,4'-C-ethyleneoxy bridged 5-methyluridine.
    Hari Y; Morikawa T; Osawa T; Obika S
    Org Lett; 2013 Jul; 15(14):3702-5. PubMed ID: 23815244
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.