BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 17154528)

  • 1. Long-range cooperative interactions modulate dimerization in SARS 3CLpro.
    Barrila J; Bacha U; Freire E
    Biochemistry; 2006 Dec; 45(50):14908-16. PubMed ID: 17154528
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism for controlling the dimer-monomer switch and coupling dimerization to catalysis of the severe acute respiratory syndrome coronavirus 3C-like protease.
    Shi J; Sivaraman J; Song J
    J Virol; 2008 May; 82(9):4620-9. PubMed ID: 18305031
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure.
    Hu T; Zhang Y; Li L; Wang K; Chen S; Chen J; Ding J; Jiang H; Shen X
    Virology; 2009 Jun; 388(2):324-34. PubMed ID: 19409595
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutation of Gly-11 on the dimer interface results in the complete crystallographic dimer dissociation of severe acute respiratory syndrome coronavirus 3C-like protease: crystal structure with molecular dynamics simulations.
    Chen S; Hu T; Zhang J; Chen J; Chen K; Ding J; Jiang H; Shen X
    J Biol Chem; 2008 Jan; 283(1):554-564. PubMed ID: 17977841
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutation of Asn28 disrupts the dimerization and enzymatic activity of SARS 3CL(pro) .
    Barrila J; Gabelli SB; Bacha U; Amzel LM; Freire E
    Biochemistry; 2010 May; 49(20):4308-17. PubMed ID: 20420403
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dynamically-driven enhancement of the catalytic machinery of the SARS 3C-like protease by the S284-T285-I286/A mutations on the extra domain.
    Lim L; Shi J; Mu Y; Song J
    PLoS One; 2014; 9(7):e101941. PubMed ID: 25036652
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The catalysis of the SARS 3C-like protease is under extensive regulation by its extra domain.
    Shi J; Song J
    FEBS J; 2006 Mar; 273(5):1035-45. PubMed ID: 16478476
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro): IMPLICATIONS FOR nsp5 REGULATION AND THE DEVELOPMENT OF ANTIVIRALS.
    Tomar S; Johnston ML; St John SE; Osswald HL; Nyalapatla PR; Paul LN; Ghosh AK; Denison MR; Mesecar AD
    J Biol Chem; 2015 Aug; 290(32):19403-22. PubMed ID: 26055715
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism for controlling the monomer-dimer conversion of SARS coronavirus main protease.
    Wu CG; Cheng SC; Chen SC; Li JY; Fang YH; Chen YH; Chou CY
    Acta Crystallogr D Biol Crystallogr; 2013 May; 69(Pt 5):747-55. PubMed ID: 23633583
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds.
    Báez-Santos YM; St John SE; Mesecar AD
    Antiviral Res; 2015 Mar; 115():21-38. PubMed ID: 25554382
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evaluating the 3C-like protease activity of SARS-Coronavirus: recommendations for standardized assays for drug discovery.
    Grum-Tokars V; Ratia K; Begaye A; Baker SC; Mesecar AD
    Virus Res; 2008 Apr; 133(1):63-73. PubMed ID: 17397958
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation and maturation of SARS-CoV main protease.
    Xia B; Kang X
    Protein Cell; 2011 Apr; 2(4):282-90. PubMed ID: 21533772
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Liberation of SARS-CoV main protease from the viral polyprotein: N-terminal autocleavage does not depend on the mature dimerization mode.
    Chen S; Jonas F; Shen C; Hilgenfeld R
    Protein Cell; 2010 Jan; 1(1):59-74. PubMed ID: 21203998
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Critical assessment of important regions in the subunit association and catalytic action of the severe acute respiratory syndrome coronavirus main protease.
    Hsu WC; Chang HC; Chou CY; Tsai PJ; Lin PI; Chang GG
    J Biol Chem; 2005 Jun; 280(24):22741-8. PubMed ID: 15831489
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs.
    Anand K; Ziebuhr J; Wadhwani P; Mesters JR; Hilgenfeld R
    Science; 2003 Jun; 300(5626):1763-7. PubMed ID: 12746549
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of novel inhibitors of the SARS coronavirus main protease 3CLpro.
    Bacha U; Barrila J; Velazquez-Campoy A; Leavitt SA; Freire E
    Biochemistry; 2004 May; 43(17):4906-12. PubMed ID: 15109248
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Key dimer interface residues impact the catalytic activity of 3CLpro, the main protease of SARS-CoV-2.
    Ferreira JC; Fadl S; Rabeh WM
    J Biol Chem; 2022 Jun; 298(6):102023. PubMed ID: 35568197
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure of the SARS coronavirus main proteinase as an active C2 crystallographic dimer.
    Xu T; Ooi A; Lee HC; Wilmouth R; Liu DX; Lescar J
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2005 Nov; 61(Pt 11):964-6. PubMed ID: 16511208
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Only one protomer is active in the dimer of SARS 3C-like proteinase.
    Chen H; Wei P; Huang C; Tan L; Liu Y; Lai L
    J Biol Chem; 2006 May; 281(20):13894-8. PubMed ID: 16565086
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Steady-state and pre-steady-state kinetic evaluation of severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro cysteine protease: development of an ion-pair model for catalysis.
    Solowiej J; Thomson JA; Ryan K; Luo C; He M; Lou J; Murray BW
    Biochemistry; 2008 Feb; 47(8):2617-30. PubMed ID: 18237196
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.