97 related articles for article (PubMed ID: 17157010)
1. 13C bis-labeled pyrroles: a tool for the identification of the rat metabolism of 3-methyl pyrrole-2,4-dicarboxylic acid 2-propyl ester 4-(1,2,2-trimethyl-propyl) ester.
Micheli F; Cavanni P; Di Fabio R; Donati D; Hamdan M; Provera S; Tranquillini ME; Vitulli G
Bioorg Med Chem Lett; 2007 Feb; 17(4):969-73. PubMed ID: 17157010
[TBL] [Abstract][Full Text] [Related]
2. 3-Methyl pyrrole-2,4-dicarboxylic acid 2-propyl ester 4-(1,2,2-trimethyl-propyl) ester: an exploration of the C-2 position. Part I.
Micheli F; Di Fabio R; Benedetti R; Capelli AM; Cavallini P; Cavanni P; Davalli S; Donati D; Feriani A; Gehanne S; Hamdan M; Maffeis M; Sabbatini FM; Tranquillini ME; Viziano MV
Farmaco; 2004 Mar; 59(3):175-83. PubMed ID: 14987980
[TBL] [Abstract][Full Text] [Related]
3. 2,4-Dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists: further characterization of 3,5-dimethyl pyrrole-2,4-dicarboxylic acid 2-propyl ester 4-(1,2,2-trimethyl-propyl) ester and structure-activity relationships.
Micheli F; Di Fabio R; Bordi F; Cavallini P; Cavanni P; Donati D; Faedo S; Maffeis M; Sabbatini FM; Tarzia G; Tranquillini ME
Bioorg Med Chem Lett; 2003 Jul; 13(13):2113-8. PubMed ID: 12798316
[TBL] [Abstract][Full Text] [Related]
4. 3-Methyl pyrrole-2,4-dicarboxylic acid 2-propyl ester 4-(1,2,2-trimethyl-propyl) ester: an exploration of the C-2 position. Part II, A solid-phase approach.
Micheli F; Di Fabio R; Cavallini P; Cavanni P; Donati D; Hamdan M; Maria Sabbatini F; Messeri T
Farmaco; 2004 Feb; 59(2):119-23. PubMed ID: 14871503
[TBL] [Abstract][Full Text] [Related]
5. From pyrroles to pyrrolo[1,2-a]pyrazinones: a new class of mGluR1 antagonists.
Micheli F; Cavanni P; Di Fabio R; Marchioro C; Donati D; Faedo S; Maffeis M; Sabbatini FM; Tranquillini ME
Bioorg Med Chem Lett; 2006 Mar; 16(5):1342-5. PubMed ID: 16337118
[TBL] [Abstract][Full Text] [Related]
6. 2,4-Dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists: an exploration of the role of the pyrrolic scaffold.
Micheli F; Di Fabio R; Cavanni P; Donati D; Faedo S; Gehanne S; Maffeis M; Marchioro C; Sabbatini FM; Tarzia G; Tranquillini ME; Viziano M
Farmaco; 2003 Oct; 58(10):1005-9. PubMed ID: 14505730
[TBL] [Abstract][Full Text] [Related]
7. Pharmacological effects of the metabotropic glutamate receptor 1 antagonist compared with those of the metabotropic glutamate receptor 5 antagonist and metabotropic glutamate receptor 2/3 agonist in rodents: detailed investigations with a selective allosteric metabotropic glutamate receptor 1 antagonist, FTIDC [4-[1-(2-fluoropyridine-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide].
Satow A; Maehara S; Ise S; Hikichi H; Fukushima M; Suzuki G; Kimura T; Tanak T; Ito S; Kawamoto H; Ohta H
J Pharmacol Exp Ther; 2008 Aug; 326(2):577-86. PubMed ID: 18487514
[TBL] [Abstract][Full Text] [Related]
8. Pharmacological characterization of a new, orally active and potent allosteric metabotropic glutamate receptor 1 antagonist, 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide (FTIDC).
Suzuki G; Kimura T; Satow A; Kaneko N; Fukuda J; Hikichi H; Sakai N; Maehara S; Kawagoe-Takaki H; Hata M; Azuma T; Ito S; Kawamoto H; Ohta H
J Pharmacol Exp Ther; 2007 Jun; 321(3):1144-53. PubMed ID: 17360958
[TBL] [Abstract][Full Text] [Related]
9. Determination of the 13C-labeling pattern of glutamate by gas chromatography-mass spectrometry.
Beylot M; David F; Brunengraber H
Anal Biochem; 1993 Aug; 212(2):532-6. PubMed ID: 8105720
[TBL] [Abstract][Full Text] [Related]
10. Novel 5-substituted 1-pyrazolol analogues of ibotenic acid: synthesis and pharmacology at glutamate receptors.
Jørgensen CG; Bräuner-Osborne H; Nielsen B; Kehler J; Clausen RP; Krogsgaard-Larsen P; Madsen U
Bioorg Med Chem; 2007 May; 15(10):3524-38. PubMed ID: 17376693
[TBL] [Abstract][Full Text] [Related]
11. Optimisation of derivatisation procedures for the determination of delta13C values of amino acids by gas chromatography/combustion/isotope ratio mass spectrometry.
Corr LT; Berstan R; Evershed RP
Rapid Commun Mass Spectrom; 2007; 21(23):3759-71. PubMed ID: 17990247
[TBL] [Abstract][Full Text] [Related]
12. Phenylethynyl-pyrrolo[1,2-a]pyrazine: a new potent and selective tool in the mGluR5 antagonists arena.
Micheli F; Bertani B; Bozzoli A; Crippa L; Cavanni P; Di Fabio R; Donati D; Marzorati P; Merlo G; Paio A; Perugini L; Zarantonello P
Bioorg Med Chem Lett; 2008 Mar; 18(6):1804-9. PubMed ID: 18304814
[TBL] [Abstract][Full Text] [Related]
13. From pyrroles to 1-oxo-2,3,4,9-tetrahydro-1H-beta-carbolines: a new class of orally bioavailable mGluR1 antagonists.
Di Fabio R; Micheli F; Alvaro G; Cavanni P; Donati D; Gagliardi T; Fontana G; Giovannini R; Maffeis M; Mingardi A; Tranquillini ME; Vitulli G
Bioorg Med Chem Lett; 2007 Apr; 17(8):2254-9. PubMed ID: 17276684
[TBL] [Abstract][Full Text] [Related]
14. Virtual screening for selective allosteric mGluR1 antagonists and structure-activity relationship investigations for coumarine derivatives.
Noeske T; Jirgensons A; Starchenkovs I; Renner S; Jaunzeme I; Trifanova D; Hechenberger M; Bauer T; Kauss V; Parsons CG; Schneider G; Weil T
ChemMedChem; 2007 Dec; 2(12):1763-73. PubMed ID: 17868161
[TBL] [Abstract][Full Text] [Related]
15. Analysis of 4-methyl-piperazine-1-carbodithioic acid 3-cyano-3,3-diphenyl-propyl ester hydrochloride and its major metabolites in rat plasma and tissues by LC-MS/MS.
Jiang X; Ling X; Han F; Li R; Cui J
J Sep Sci; 2007 Aug; 30(13):2080-5. PubMed ID: 17638372
[TBL] [Abstract][Full Text] [Related]
16. Synergism of virtual screening and medicinal chemistry: identification and optimization of allosteric antagonists of metabotropic glutamate receptor 1.
Noeske T; Trifanova D; Kauss V; Renner S; Parsons CG; Schneider G; Weil T
Bioorg Med Chem; 2009 Aug; 17(15):5708-15. PubMed ID: 19574055
[TBL] [Abstract][Full Text] [Related]
17. The potent non-competitive mGlu1 receptor antagonist BAY 36-7620 differentially affects synaptic plasticity in area cornu ammonis 1 of rat hippocampal slices and impairs acquisition in the water maze task in mice.
Schröder UH; Müller T; Schreiber R; Stolle A; Zuschratter W; Balschun D; Jork R; Reymann KG
Neuroscience; 2008 Nov; 157(2):385-95. PubMed ID: 18832015
[TBL] [Abstract][Full Text] [Related]
18. Synthesis of [19, 35, 36-(13)C(3)]-labeled TAK779 as a molecular probe.
Konno H; Aimoto S; Smith SO; Nosaka K; Akaji K
Bioorg Med Chem; 2009 Aug; 17(16):5769-74. PubMed ID: 19640721
[TBL] [Abstract][Full Text] [Related]
19. Metabolite identification via LC-SPE-NMR-MS of the in vitro biooxidation products of a lead mGlu5 allosteric antagonist and impact on the improvement of metabolic stability in the series.
Ceccarelli SM; Schlotterbeck G; Boissin P; Binder M; Buettelmann B; Hanlon S; Jaeschke G; Kolczewski S; Kupfer E; Peters JU; Porter RH; Prinssen EP; Rueher M; Ruf I; Spooren W; Stämpfli A; Vieira E
ChemMedChem; 2008 Jan; 3(1):136-44. PubMed ID: 17994660
[TBL] [Abstract][Full Text] [Related]
20. Identification of a novel transmembrane domain involved in the negative modulation of mGluR1 using a newly discovered allosteric mGluR1 antagonist, 3-cyclohexyl-5-fluoro-6-methyl-7-(2-morpholin-4-ylethoxy)-4H-chromen-4-one.
Fukuda J; Suzuki G; Kimura T; Nagatomi Y; Ito S; Kawamoto H; Ozaki S; Ohta H
Neuropharmacology; 2009 Sep; 57(4):438-45. PubMed ID: 19559036
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]