BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

127 related articles for article (PubMed ID: 17161946)

  • 1. Synthesis and biological activation of an ethylene glycol-linked amino acid conjugate of cyclic cidofovir.
    Eriksson U; Hilfinger JM; Kim JS; Mitchell S; Kijek P; Borysko KZ; Breitenbach JM; Drach JC; Kashemirov BA; McKenna CE
    Bioorg Med Chem Lett; 2007 Feb; 17(3):583-6. PubMed ID: 17161946
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Serine peptide phosphoester prodrugs of cyclic cidofovir: synthesis, transport, and antiviral activity.
    Eriksson U; Peterson LW; Kashemirov BA; Hilfinger JM; Drach JC; Borysko KZ; Breitenbach JM; Kim JS; Mitchell S; Kijek P; McKenna CE
    Mol Pharm; 2008; 5(4):598-609. PubMed ID: 18481868
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Serine side chain-linked peptidomimetic conjugates of cyclic HPMPC and HPMPA: synthesis and interaction with hPEPT1.
    Peterson LW; Sala-Rabanal M; Krylov IS; Serpi M; Kashemirov BA; McKenna CE
    Mol Pharm; 2010 Dec; 7(6):2349-61. PubMed ID: 20929265
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Puromycin-sensitive aminopeptidase: an antiviral prodrug activating enzyme.
    Tehler U; Nelson CH; Peterson LW; Provoda CJ; Hilfinger JM; Lee KD; McKenna CE; Amidon GL
    Antiviral Res; 2010 Mar; 85(3):482-9. PubMed ID: 19969024
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Conversion of 1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosine to cidofovir by an intracellular cyclic CMP phosphodiesterase.
    Mendel DB; Cihlar T; Moon K; Chen MS
    Antimicrob Agents Chemother; 1997 Mar; 41(3):641-6. PubMed ID: 9056007
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tyrosine-based 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) prodrugs: synthesis, stability, antiviral activity, and in vivo transport studies.
    Zakharova VM; Serpi M; Krylov IS; Peterson LW; Breitenbach JM; Borysko KZ; Drach JC; Collins M; Hilfinger JM; Kashemirov BA; McKenna CE
    J Med Chem; 2011 Aug; 54(16):5680-93. PubMed ID: 21812420
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pharmacokinetics of salicylate ester prodrugs of cyclic HPMPC in dogs.
    Oliyai R; Arimilli MN; Jones RJ; Lee WA
    Nucleosides Nucleotides Nucleic Acids; 2001; 20(4-7):1411-4. PubMed ID: 11563033
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aryl ester prodrugs of cyclic HPMPC. I: Physicochemical characterization and in vitro biological stability.
    Oliyai R; Shaw JP; Sueoka-Lennen CM; Cundy KC; Arimilli MN; Jones RJ; Lee WA
    Pharm Res; 1999 Nov; 16(11):1687-93. PubMed ID: 10571273
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chemical and enzymatic stability of amino acid prodrugs containing methoxy, ethoxy and propylene glycol linkers.
    Gupta D; Gupta SV; Lee KD; Amidon GL
    Mol Pharm; 2009; 6(5):1604-11. PubMed ID: 19566080
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Propylene glycol-linked amino acid/dipeptide diester prodrugs of oleanolic acid for PepT1-mediated transport: synthesis, intestinal permeability, and pharmacokinetics.
    Cao F; Gao Y; Wang M; Fang L; Ping Q
    Mol Pharm; 2013 Apr; 10(4):1378-87. PubMed ID: 23339520
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl] cytosine, an intracellular prodrug for (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine with improved therapeutic index in vivo.
    Bischofberger N; Hitchcock MJ; Chen MS; Barkhimer DB; Cundy KC; Kent KM; Lacy SA; Lee WA; Li ZH; Mendel DB
    Antimicrob Agents Chemother; 1994 Oct; 38(10):2387-91. PubMed ID: 7840575
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pharmacokinetics, bioavailability, metabolism, and tissue distribution of cidofovir (HPMPC) and cyclic HPMPC in rats.
    Cundy KC; Bidgood AM; Lynch G; Shaw JP; Griffin L; Lee WA
    Drug Metab Dispos; 1996 Jul; 24(7):745-52. PubMed ID: 8818571
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enhanced chemical stability of the intracellular prodrug, 1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosine, relative to its parent compound, cidofovir.
    Oliyai R; Lee WA; Visor GC; Yuan LC
    Int J Pharm; 1999 Mar; 179(2):257-65. PubMed ID: 10053218
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transporter-targeted lipid prodrugs of cyclic cidofovir: a potential approach for the treatment of cytomegalovirus retinitis.
    Gokulgandhi MR; Barot M; Bagui M; Pal D; Mitra AK
    J Pharm Sci; 2012 Sep; 101(9):3249-63. PubMed ID: 22499243
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of cidofovir and (S)-HPMPA ether lipid prodrugs.
    Beadle JR
    Curr Protoc Nucleic Acid Chem; 2007 Jun; Chapter 15():Unit 15.2. PubMed ID: 18428972
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Improved Protease-Targeting and Biopharmaceutical Properties of Novel Prodrugs of Ganciclovir.
    Sun K; Xu H; Hilfinger JL; Lee KD; Provoda CJ; Sabit H; Amidon GL
    Mol Pharm; 2018 Feb; 15(2):410-419. PubMed ID: 29251944
    [TBL] [Abstract][Full Text] [Related]  

  • 17. N(4)-Acyl derivatives as lipophilic prodrugs of cidofovir and its 5-azacytosine analogue, (S)-HPMP-5-azaC: chemistry and antiviral activity.
    Krečmerová M; Pohl R; Masojídková M; Balzarini J; Snoeck R; Andrei G
    Bioorg Med Chem; 2014 May; 22(10):2896-906. PubMed ID: 24731540
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of a novel intraocular drug-delivery system using crystalline lipid antiviral prodrugs of ganciclovir and cyclic cidofovir.
    Cheng L; Hostetler KY; Lee J; Koh HJ; Beadle JR; Bessho K; Toyoguchi M; Aldern K; Bovet JM; Freeman WR
    Invest Ophthalmol Vis Sci; 2004 Nov; 45(11):4138-44. PubMed ID: 15505067
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ethylene glycol-linked amino acid diester prodrugs of oleanolic acid for PepT1-mediated transport: synthesis, intestinal permeability and pharmacokinetics.
    Cao F; Jia J; Yin Z; Gao Y; Sha L; Lai Y; Ping Q; Zhang Y
    Mol Pharm; 2012 Aug; 9(8):2127-35. PubMed ID: 22352697
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bifunctional peptidomimetic prodrugs of didanosine for improved intestinal permeability and enhanced acidic stability: synthesis, transepithelial transport, chemical stability and pharmacokinetics.
    Yan Z; Sun J; Chang Y; Liu Y; Fu Q; Xu Y; Sun Y; Pu X; Zhang Y; Jing Y; Yin S; Zhu M; Wang Y; He Z
    Mol Pharm; 2011 Apr; 8(2):319-29. PubMed ID: 21280612
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.