221 related articles for article (PubMed ID: 17168761)
1. Quaternary structure, substrate selectivity and inhibitor design for SARS 3C-like proteinase.
Lai L; Han X; Chen H; Wei P; Huang C; Liu S; Fan K; Zhou L; Liu Z; Pei J; Liu Y
Curr Pharm Des; 2006; 12(35):4555-64. PubMed ID: 17168761
[TBL] [Abstract][Full Text] [Related]
2. Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro.
Chen L; Gui C; Luo X; Yang Q; Günther S; Scandella E; Drosten C; Bai D; He X; Ludewig B; Chen J; Luo H; Yang Y; Yang Y; Zou J; Thiel V; Chen K; Shen J; Shen X; Jiang H
J Virol; 2005 Jun; 79(11):7095-103. PubMed ID: 15890949
[TBL] [Abstract][Full Text] [Related]
3. Drug design targeting the main protease, the Achilles' heel of coronaviruses.
Yang H; Bartlam M; Rao Z
Curr Pharm Des; 2006; 12(35):4573-90. PubMed ID: 17168763
[TBL] [Abstract][Full Text] [Related]
4. Maturation mechanism of severe acute respiratory syndrome (SARS) coronavirus 3C-like proteinase.
Li C; Qi Y; Teng X; Yang Z; Wei P; Zhang C; Tan L; Zhou L; Liu Y; Lai L
J Biol Chem; 2010 Sep; 285(36):28134-40. PubMed ID: 20489209
[TBL] [Abstract][Full Text] [Related]
5. Substrate specificity profiling and identification of a new class of inhibitor for the major protease of the SARS coronavirus.
Goetz DH; Choe Y; Hansell E; Chen YT; McDowell M; Jonsson CB; Roush WR; McKerrow J; Craik CS
Biochemistry; 2007 Jul; 46(30):8744-52. PubMed ID: 17605471
[TBL] [Abstract][Full Text] [Related]
6. Development of a red-shifted fluorescence-based assay for SARS-coronavirus 3CL protease: identification of a novel class of anti-SARS agents from the tropical marine sponge Axinella corrugata.
Hamill P; Hudson D; Kao RY; Chow P; Raj M; Xu H; Richer MJ; Jean F
Biol Chem; 2006 Aug; 387(8):1063-74. PubMed ID: 16895476
[TBL] [Abstract][Full Text] [Related]
7. High-throughput screening identifies inhibitors of the SARS coronavirus main proteinase.
Blanchard JE; Elowe NH; Huitema C; Fortin PD; Cechetto JD; Eltis LD; Brown ED
Chem Biol; 2004 Oct; 11(10):1445-53. PubMed ID: 15489171
[TBL] [Abstract][Full Text] [Related]
8. Virtual screening of novel noncovalent inhibitors for SARS-CoV 3C-like proteinase.
Liu Z; Huang C; Fan K; Wei P; Chen H; Liu S; Pei J; Shi L; Li B; Yang K; Liu Y; Lai L
J Chem Inf Model; 2005; 45(1):10-17. PubMed ID: 15667124
[TBL] [Abstract][Full Text] [Related]
9. The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds.
Báez-Santos YM; St John SE; Mesecar AD
Antiviral Res; 2015 Mar; 115():21-38. PubMed ID: 25554382
[TBL] [Abstract][Full Text] [Related]
10. The interaction between severe acute respiratory syndrome coronavirus 3C-like proteinase and a dimeric inhibitor by capillary electrophoresis.
Ding L; Zhang XX; Wei P; Fan K; Lai L
Anal Biochem; 2005 Aug; 343(1):159-65. PubMed ID: 15935325
[TBL] [Abstract][Full Text] [Related]
11. Biosynthesis, purification, and substrate specificity of severe acute respiratory syndrome coronavirus 3C-like proteinase.
Fan K; Wei P; Feng Q; Chen S; Huang C; Ma L; Lai B; Pei J; Liu Y; Chen J; Lai L
J Biol Chem; 2004 Jan; 279(3):1637-42. PubMed ID: 14561748
[TBL] [Abstract][Full Text] [Related]
12. Inhibitor recognition specificity of MERS-CoV papain-like protease may differ from that of SARS-CoV.
Lee H; Lei H; Santarsiero BD; Gatuz JL; Cao S; Rice AJ; Patel K; Szypulinski MZ; Ojeda I; Ghosh AK; Johnson ME
ACS Chem Biol; 2015 Jun; 10(6):1456-65. PubMed ID: 25746232
[TBL] [Abstract][Full Text] [Related]
13. Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome-coronavirus papain-like protease.
Ghosh AK; Takayama J; Aubin Y; Ratia K; Chaudhuri R; Baez Y; Sleeman K; Coughlin M; Nichols DB; Mulhearn DC; Prabhakar BS; Baker SC; Johnson ME; Mesecar AD
J Med Chem; 2009 Aug; 52(16):5228-40. PubMed ID: 19645480
[TBL] [Abstract][Full Text] [Related]
14. Inhibitor design for SARS coronavirus main protease based on "distorted key theory".
Du QS; Sun H; Chou KC
Med Chem; 2007 Jan; 3(1):1-6. PubMed ID: 17266617
[TBL] [Abstract][Full Text] [Related]
15. Discovery of unsymmetrical aromatic disulfides as novel inhibitors of SARS-CoV main protease: Chemical synthesis, biological evaluation, molecular docking and 3D-QSAR study.
Wang L; Bao BB; Song GQ; Chen C; Zhang XM; Lu W; Wang Z; Cai Y; Li S; Fu S; Song FH; Yang H; Wang JG
Eur J Med Chem; 2017 Sep; 137():450-461. PubMed ID: 28624700
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and evaluation of pyrazolone compounds as SARS-coronavirus 3C-like protease inhibitors.
Ramajayam R; Tan KP; Liu HG; Liang PH
Bioorg Med Chem; 2010 Nov; 18(22):7849-54. PubMed ID: 20947359
[TBL] [Abstract][Full Text] [Related]
17. Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.
Lee CC; Kuo CJ; Hsu MF; Liang PH; Fang JM; Shie JJ; Wang AH
FEBS Lett; 2007 Nov; 581(28):5454-8. PubMed ID: 17981158
[TBL] [Abstract][Full Text] [Related]
18. Sometimes intermediates. Do the job!
Hilgenfeld R; Pumpor K
Chem Biol; 2006 Mar; 13(3):235-6. PubMed ID: 16638527
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors.
Chen LR; Wang YC; Lin YW; Chou SY; Chen SF; Liu LT; Wu YT; Kuo CJ; Chen TS; Juang SH
Bioorg Med Chem Lett; 2005 Jun; 15(12):3058-62. PubMed ID: 15896959
[TBL] [Abstract][Full Text] [Related]
20. 3C-like proteinase from SARS coronavirus catalyzes substrate hydrolysis by a general base mechanism.
Huang C; Wei P; Fan K; Liu Y; Lai L
Biochemistry; 2004 Apr; 43(15):4568-74. PubMed ID: 15078103
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]