143 related articles for article (PubMed ID: 17175524)
1. A novel inhibitor of Mycobacterium tuberculosis pantothenate synthetase.
White EL; Southworth K; Ross L; Cooley S; Gill RB; Sosa MI; Manouvakhova A; Rasmussen L; Goulding C; Eisenberg D; Fletcher TM
J Biomol Screen; 2007 Feb; 12(1):100-5. PubMed ID: 17175524
[TBL] [Abstract][Full Text] [Related]
2. Crystal structure of the pantothenate synthetase from Mycobacterium tuberculosis, snapshots of the enzyme in action.
Wang S; Eisenberg D
Biochemistry; 2006 Feb; 45(6):1554-61. PubMed ID: 16460002
[TBL] [Abstract][Full Text] [Related]
3. Active site residues in Mycobacterium tuberculosis pantothenate synthetase required in the formation and stabilization of the adenylate intermediate.
Zheng R; Dam TK; Brewer CF; Blanchard JS
Biochemistry; 2004 Jun; 43(22):7171-8. PubMed ID: 15170354
[TBL] [Abstract][Full Text] [Related]
4. A discovery of novel Mycobacterium tuberculosis pantothenate synthetase inhibitors based on the molecular mechanism of actinomycin D inhibition.
Yang Y; Gao P; Liu Y; Ji X; Gan M; Guan Y; Hao X; Li Z; Xiao C
Bioorg Med Chem Lett; 2011 Jul; 21(13):3943-6. PubMed ID: 21641210
[TBL] [Abstract][Full Text] [Related]
5. A comparison of the dynamics of pantothenate synthetase from M. tuberculosis and E. coli: computational studies.
Tan YS; Fuentes G; Verma C
Proteins; 2011 Jun; 79(6):1715-27. PubMed ID: 21425349
[TBL] [Abstract][Full Text] [Related]
6. The design and synthesis of inhibitors of pantothenate synthetase.
Tuck KL; Saldanha SA; Birch LM; Smith AG; Abell C
Org Biomol Chem; 2006 Oct; 4(19):3598-610. PubMed ID: 16990935
[TBL] [Abstract][Full Text] [Related]
7. Steady-state and pre-steady-state kinetic analysis of Mycobacterium tuberculosis pantothenate synthetase.
Zheng R; Blanchard JS
Biochemistry; 2001 Oct; 40(43):12904-12. PubMed ID: 11669627
[TBL] [Abstract][Full Text] [Related]
8. Reaction intermediate analogues as bisubstrate inhibitors of pantothenate synthetase.
Xu Z; Yin W; Martinelli LK; Evans J; Chen J; Yu Y; Wilson DJ; Mizrahi V; Qiao C; Aldrich CC
Bioorg Med Chem; 2014 Mar; 22(5):1726-35. PubMed ID: 24507827
[TBL] [Abstract][Full Text] [Related]
9. A high-throughput screen against pantothenate synthetase (PanC) identifies 3-biphenyl-4-cyanopyrrole-2-carboxylic acids as a new class of inhibitor with activity against Mycobacterium tuberculosis.
Kumar A; Casey A; Odingo J; Kesicki EA; Abrahams G; Vieth M; Masquelin T; Mizrahi V; Hipskind PA; Sherman DR; Parish T
PLoS One; 2013; 8(11):e72786. PubMed ID: 24244263
[TBL] [Abstract][Full Text] [Related]
10. Structure-guided design of thiazolidine derivatives as Mycobacterium tuberculosis pantothenate synthetase inhibitors.
Devi PB; Samala G; Sridevi JP; Saxena S; Alvala M; Salina EG; Sriram D; Yogeeswari P
ChemMedChem; 2014 Nov; 9(11):2538-47. PubMed ID: 25155986
[TBL] [Abstract][Full Text] [Related]
11. Development of novel tetrahydrothieno[2,3-c]pyridine-3-carboxamide based Mycobacterium tuberculosis pantothenate synthetase inhibitors: molecular hybridization from known antimycobacterial leads.
Samala G; Devi PB; Nallangi R; Sridevi JP; Saxena S; Yogeeswari P; Sriram D
Bioorg Med Chem; 2014 Mar; 22(6):1938-47. PubMed ID: 24565972
[TBL] [Abstract][Full Text] [Related]
12. Design of Novel Mycobacterium tuberculosis Pantothenate Synthetase Inhibitors: Virtual Screening, Synthesis and In Vitro Biological Activities.
Devi PB; Jogula S; Reddy AP; Saxena S; Sridevi JP; Sriram D; Yogeeswari P
Mol Inform; 2015 Feb; 34(2-3):147-59. PubMed ID: 27490037
[TBL] [Abstract][Full Text] [Related]
13. A novel isoform of pantothenate synthetase in the Archaea.
Ronconi S; Jonczyk R; Genschel U
FEBS J; 2008 Jun; 275(11):2754-64. PubMed ID: 18422645
[TBL] [Abstract][Full Text] [Related]
14. Application of fragment growing and fragment linking to the discovery of inhibitors of Mycobacterium tuberculosis pantothenate synthetase.
Hung AW; Silvestre HL; Wen S; Ciulli A; Blundell TL; Abell C
Angew Chem Int Ed Engl; 2009; 48(45):8452-6. PubMed ID: 19780086
[No Abstract] [Full Text] [Related]
15. Positional isotope exchange analysis of the pantothenate synthetase reaction.
Williams L; Zheng R; Blanchard JS; Raushel FM
Biochemistry; 2003 May; 42(17):5108-13. PubMed ID: 12718554
[TBL] [Abstract][Full Text] [Related]
16. Development of 3-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine derivatives as novel Mycobacterium tuberculosis pantothenate synthetase inhibitors.
Samala G; Devi PB; Nallangi R; Yogeeswari P; Sriram D
Eur J Med Chem; 2013 Nov; 69():356-64. PubMed ID: 24077526
[TBL] [Abstract][Full Text] [Related]
17. Substrate-induced closing of the active site revealed by the crystal structure of pantothenate synthetase from Staphylococcus aureus.
Satoh A; Konishi S; Tamura H; Stickland HG; Whitney HM; Smith AG; Matsumura H; Inoue T
Biochemistry; 2010 Aug; 49(30):6400-10. PubMed ID: 20568730
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of Mycobacterium tuberculosis pantothenate synthetase by analogues of the reaction intermediate.
Ciulli A; Scott DE; Ando M; Reyes F; Saldanha SA; Tuck KL; Chirgadze DY; Blundell TL; Abell C
Chembiochem; 2008 Nov; 9(16):2606-11. PubMed ID: 18821554
[No Abstract] [Full Text] [Related]
19. Identification and development of 2-methylimidazo[1,2-a]pyridine-3-carboxamides as Mycobacterium tuberculosis pantothenate synthetase inhibitors.
Samala G; Nallangi R; Devi PB; Saxena S; Yadav R; Sridevi JP; Yogeeswari P; Sriram D
Bioorg Med Chem; 2014 Aug; 22(15):4223-32. PubMed ID: 24953948
[TBL] [Abstract][Full Text] [Related]
20. Crystal structures of a pantothenate synthetase from M. tuberculosis and its complexes with substrates and a reaction intermediate.
Wang S; Eisenberg D
Protein Sci; 2003 May; 12(5):1097-108. PubMed ID: 12717031
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]