577 related articles for article (PubMed ID: 17184892)
1. Deconjugation of N-glucuronide conjugated metabolites with hydrazine hydrate--biomarkers for exposure to the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Frandsen H
Food Chem Toxicol; 2007 May; 45(5):863-70. PubMed ID: 17184892
[TBL] [Abstract][Full Text] [Related]
2. Biomonitoring of urinary metabolites of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) following human consumption of cooked chicken.
Frandsen H
Food Chem Toxicol; 2008 Sep; 46(9):3200-5. PubMed ID: 18692111
[TBL] [Abstract][Full Text] [Related]
3. N-acetyltransferase-dependent activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine: formation of 2-amino-1-methyl-6-(5-hydroxy)phenylimidazo [4,5-b]pyridine, a possible biomarker for the reactive dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Frandsen H; Alexander J
Carcinogenesis; 2000 Jun; 21(6):1197-203. PubMed ID: 10837010
[TBL] [Abstract][Full Text] [Related]
4. The impact of glucuronidation on the bioactivation and DNA adduction of the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in vivo.
Malfatti MA; Ubick EA; Felton JS
Carcinogenesis; 2005 Nov; 26(11):2019-28. PubMed ID: 15944213
[TBL] [Abstract][Full Text] [Related]
5. The direct glucuronidation of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) by human and rabbit liver microsomes.
Styczynski PB; Blackmon RC; Groopman JD; Kensler TW
Chem Res Toxicol; 1993; 6(6):846-51. PubMed ID: 8117924
[TBL] [Abstract][Full Text] [Related]
6. Metabolism of the food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the rat and other rodents.
Alexander J; Fossum BH; Reistad R; Holme JA
Princess Takamatsu Symp; 1995; 23():113-22. PubMed ID: 8844802
[TBL] [Abstract][Full Text] [Related]
7. The capability of rat colon tissue slices to metabolize the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Malfatti MA; Connors MS; Mauthe RJ; Felton JS
Cancer Res; 1996 Jun; 56(11):2550-5. PubMed ID: 8653696
[TBL] [Abstract][Full Text] [Related]
8. Urinary excretion of unmetabolized and phase II conjugates of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in humans: relationship to cytochrome P4501A2 and N-acetyltransferase activity.
Stillwell WG; Kidd LC; Wishnok JS; Tannenbaum SR; Sinha R
Cancer Res; 1997 Aug; 57(16):3457-64. PubMed ID: 9270013
[TBL] [Abstract][Full Text] [Related]
9. A comprehensive approach to the profiling of the cooked meat carcinogens 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, and their metabolites in human urine.
Gu D; McNaughton L; Lemaster D; Lake BG; Gooderham NJ; Kadlubar FF; Turesky RJ
Chem Res Toxicol; 2010 Apr; 23(4):788-801. PubMed ID: 20192249
[TBL] [Abstract][Full Text] [Related]
10. Development and validation of a liquid chromatography-tandem mass spectrometry assay for the analysis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and its metabolite 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in plasma, urine, bile, intestinal contents, faeces and eight selected tissues from mice.
Teunissen SF; Vlaming ML; Rosing H; Schellens JH; Schinkel AH; Beijnen JH
J Chromatogr B Analyt Technol Biomed Life Sci; 2010 Sep; 878(25):2353-62. PubMed ID: 20708442
[TBL] [Abstract][Full Text] [Related]
11. 2-Amino-1-methyl-6-(5-hydroxy-)phenylimidazo[4,5-b]pyridine (5-OH-PhIP), a biomarker for the genotoxic dose of the heterocyclic amine, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Frandsen H; Frederiksen H; Alexander J
Food Chem Toxicol; 2002 Aug; 40(8):1125-30. PubMed ID: 12067574
[TBL] [Abstract][Full Text] [Related]
12. UGT1A1 polymorphisms are important determinants of dietary carcinogen detoxification in the liver.
Girard H; Thibaudeau J; Court MH; Fortier LC; Villeneuve L; Caron P; Hao Q; von Moltke LL; Greenblatt DJ; Guillemette C
Hepatology; 2005 Aug; 42(2):448-57. PubMed ID: 15986396
[TBL] [Abstract][Full Text] [Related]
13. Metabolites of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP) in human urine after consumption of charbroiled or fried beef.
Strickland PT; Qian Z; Friesen MD; Rothman N; Sinha R
Mutat Res; 2002 Sep; 506-507():163-73. PubMed ID: 12351156
[TBL] [Abstract][Full Text] [Related]
14. Biomonitoring of dietary heterocyclic amines and metabolites in urine by liquid phase microextraction: 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), a possible biomarker of exposure to dietary PhIP.
Busquets R; Frandsen H; Jönsson JÅ; Puignou L; Galceran MT; Skog K
Chem Res Toxicol; 2013 Feb; 26(2):233-40. PubMed ID: 23276304
[TBL] [Abstract][Full Text] [Related]
15. Intestinal bacteria metabolize the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine following consumption of a single cooked chicken meal in humans.
Vanhaecke L; Knize MG; Noppe H; De Brabander H; Verstraete W; Van de Wiele T
Food Chem Toxicol; 2008 Jan; 46(1):140-8. PubMed ID: 17766021
[TBL] [Abstract][Full Text] [Related]
16. Metabolic activation and DNA adduct detection of PhIP in dogs, rats, and humans in relation to urinary bladder and colon carcinogenesis.
Kadlubar F; Kaderlik RK; Mulder GJ; Lin D; Butler MA; Teitel CH; Minchin RF; Ilett KF; Friesen MD; Bartsch H
Princess Takamatsu Symp; 1995; 23():207-13. PubMed ID: 8844812
[TBL] [Abstract][Full Text] [Related]
17. The effect of UDP-glucuronosyltransferase 1A1 expression on the mutagenicity and metabolism of the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in CHO cells.
Malfatti MA; Wu RW; Felton JS
Mutat Res; 2005 Mar; 570(2):205-14. PubMed ID: 15708579
[TBL] [Abstract][Full Text] [Related]
18. Identification of urine metabolites of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine following consumption of a single cooked chicken meal in humans.
Kulp KS; Knize MG; Malfatti MA; Salmon CP; Felton JS
Carcinogenesis; 2000 Nov; 21(11):2065-72. PubMed ID: 11062169
[TBL] [Abstract][Full Text] [Related]
19. Human and Escherichia coli beta-glucuronidase hydrolysis of glucuronide conjugates of benzidine and 4-aminobiphenyl, and their hydroxy metabolites.
Zenser TV; Lakshmi VM; Davis BB
Drug Metab Dispos; 1999 Sep; 27(9):1064-7. PubMed ID: 10460807
[TBL] [Abstract][Full Text] [Related]
20. Urinary N2-(2'-deoxyguanosin-8-yl)PhIP as a biomarker for PhIP exposure.
Fang M; Edwards RJ; Bartlet-Jones M; Taylor GW; Murray S; Boobis AR
Carcinogenesis; 2004 Jun; 25(6):1053-62. PubMed ID: 14742322
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]