These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury. Cubero FJ; Zoubek ME; Hu W; Peng J; Zhao G; Nevzorova YA; Al Masaoudi M; Bechmann LP; Boekschoten MV; Muller M; Preisinger C; Gassler N; Canbay AE; Luedde T; Davis RJ; Liedtke C; Trautwein C Gastroenterology; 2016 Apr; 150(4):968-81. PubMed ID: 26708719 [TBL] [Abstract][Full Text] [Related]
3. c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity. Gunawan BK; Liu ZX; Han D; Hanawa N; Gaarde WA; Kaplowitz N Gastroenterology; 2006 Jul; 131(1):165-78. PubMed ID: 16831600 [TBL] [Abstract][Full Text] [Related]
6. Dihydromyricetin alleviates carbon tetrachloride-induced acute liver injury via JNK-dependent mechanism in mice. Xie J; Liu J; Chen TM; Lan Q; Zhang QY; Liu B; Dai D; Zhang WD; Hu LP; Zhu RZ World J Gastroenterol; 2015 May; 21(18):5473-81. PubMed ID: 25987769 [TBL] [Abstract][Full Text] [Related]
7. c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity. Saito C; Lemasters JJ; Jaeschke H Toxicol Appl Pharmacol; 2010 Jul; 246(1-2):8-17. PubMed ID: 20423716 [TBL] [Abstract][Full Text] [Related]
8. An inhibitor of c-Jun NH2-terminal kinase, SP600125, protects mice from D-galactosamine/lipopolysaccharide-induced hepatic failure by modulating BH3-only proteins. Takamura M; Matsuda Y; Yamagiwa S; Tamura Y; Honda Y; Suzuki K; Ichida T; Aoyagi Y Life Sci; 2007 Mar; 80(14):1335-44. PubMed ID: 17300814 [TBL] [Abstract][Full Text] [Related]
9. Mechanisms of acetaminophen-induced cell death in primary human hepatocytes. Xie Y; McGill MR; Dorko K; Kumer SC; Schmitt TM; Forster J; Jaeschke H Toxicol Appl Pharmacol; 2014 Sep; 279(3):266-274. PubMed ID: 24905542 [TBL] [Abstract][Full Text] [Related]
10. The TGFβ1 Receptor Antagonist GW788388 Reduces JNK Activation and Protects Against Acetaminophen Hepatotoxicity in Mice. McMillin M; Grant S; Frampton G; Petrescu AD; Williams E; Jefferson B; DeMorrow S Toxicol Sci; 2019 May; 170(2):549-561. PubMed ID: 31132129 [TBL] [Abstract][Full Text] [Related]
11. Fluorofenidone protects against acute liver failure in mice by regulating MKK4/JNK pathway. Gu L; He X; Zhang Y; Li S; Tang J; Ma R; Yang X; Huang H; Peng Y; Xie Y; Peng Z; Meng J; Hu G; Tao L; Liu X; Yang H Biomed Pharmacother; 2023 Aug; 164():114844. PubMed ID: 37224750 [TBL] [Abstract][Full Text] [Related]
12. Role of c-Jun N-terminal kinase (JNK) in regulating tumor necrosis factor-alpha (TNF-alpha) mediated increase of acetaminophen (APAP) and chlorpromazine (CPZ) toxicity in murine hepatocytes. Gandhi A; Guo T; Ghose R J Toxicol Sci; 2010 Apr; 35(2):163-73. PubMed ID: 20371967 [TBL] [Abstract][Full Text] [Related]
13. Differential requirement for c-Jun NH2-terminal kinase in TNFalpha- and Fas-mediated apoptosis in hepatocytes. Schwabe RF; Uchinami H; Qian T; Bennett BL; Lemasters JJ; Brenner DA FASEB J; 2004 Apr; 18(6):720-2. PubMed ID: 14766793 [TBL] [Abstract][Full Text] [Related]
14. Metformin ameliorates acetaminophen hepatotoxicity via Gadd45β-dependent regulation of JNK signaling in mice. Kim YH; Hwang JH; Kim KS; Noh JR; Choi DH; Kim DK; Tadi S; Yim YH; Choi HS; Lee CH J Hepatol; 2015 Jul; 63(1):75-82. PubMed ID: 25681557 [TBL] [Abstract][Full Text] [Related]
15. Protective Role of microRNA-31 in Acetaminophen-Induced Liver Injury: A Negative Regulator of c-Jun N-Terminal Kinase (JNK) Signaling Pathway. Zheng J; Zhou H; Yang T; Liu J; Qin T; Gu X; Wu J; Zhang Y; Wang H; Tang Y; Xue F; Mao Y; Xia Q Cell Mol Gastroenterol Hepatol; 2021; 12(5):1789-1807. PubMed ID: 34311140 [TBL] [Abstract][Full Text] [Related]
17. TAT-apoptosis repressor with caspase recruitment domain protein transduction rescues mice from fulminant liver failure. An J; Harms C; Lättig-Tünnemann G; Sellge G; Mandić AD; Malato Y; Heuser A; Endres M; Trautwein C; Donath S Hepatology; 2012 Aug; 56(2):715-26. PubMed ID: 22392694 [TBL] [Abstract][Full Text] [Related]
18. [Risk of acute hepatic insufficiency in children due to chronic accidental overdose of paracetamol (acetaminophen)]. Hameleers-Snijders P; Hogeveen M; Smeitink JA; Kramers C; Draaisma JM Ned Tijdschr Geneeskd; 2007 Apr; 151(16):897-900. PubMed ID: 17500339 [TBL] [Abstract][Full Text] [Related]
19. Protective role of c-Jun N-terminal kinase 2 in acetaminophen-induced liver injury. Bourdi M; Korrapati MC; Chakraborty M; Yee SB; Pohl LR Biochem Biophys Res Commun; 2008 Sep; 374(1):6-10. PubMed ID: 18586006 [TBL] [Abstract][Full Text] [Related]
20. Editor's Highlight: Metformin Protects Against Acetaminophen Hepatotoxicity by Attenuation of Mitochondrial Oxidant Stress and Dysfunction. Du K; Ramachandran A; Weemhoff JL; Chavan H; Xie Y; Krishnamurthy P; Jaeschke H Toxicol Sci; 2016 Dec; 154(2):214-226. PubMed ID: 27562556 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]