BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 17185403)

  • 1. For the ZDF rat, "Breaking up is hard to do": dissociation of the GK:GKRP complex.
    Lange AJ
    Am J Physiol Regul Integr Comp Physiol; 2007 Apr; 292(4):R1379-80. PubMed ID: 17185403
    [No Abstract]   [Full Text] [Related]  

  • 2. A defect in glucose-induced dissociation of glucokinase from the regulatory protein in Zucker diabetic fatty rats in the early stage of diabetes.
    Shin JS; Torres TP; Catlin RL; Donahue EP; Shiota M
    Am J Physiol Regul Integr Comp Physiol; 2007 Apr; 292(4):R1381-90. PubMed ID: 17204595
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glucose toxicity is responsible for the development of impaired regulation of endogenous glucose production and hepatic glucokinase in Zucker diabetic fatty rats.
    Fujimoto Y; Torres TP; Donahue EP; Shiota M
    Diabetes; 2006 Sep; 55(9):2479-90. PubMed ID: 16936196
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Restoration of hepatic glucokinase expression corrects hepatic glucose flux and normalizes plasma glucose in zucker diabetic fatty rats.
    Torres TP; Catlin RL; Chan R; Fujimoto Y; Sasaki N; Printz RL; Newgard CB; Shiota M
    Diabetes; 2009 Jan; 58(1):78-86. PubMed ID: 18952838
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular basis for the role of glucokinase regulatory protein as the allosteric switch for glucokinase.
    Choi JM; Seo MH; Kyeong HH; Kim E; Kim HS
    Proc Natl Acad Sci U S A; 2013 Jun; 110(25):10171-6. PubMed ID: 23733961
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acetylation of glucokinase regulatory protein decreases glucose metabolism by suppressing glucokinase activity.
    Park JM; Kim TH; Jo SH; Kim MY; Ahn YH
    Sci Rep; 2015 Dec; 5():17395. PubMed ID: 26620281
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An allosteric activator of glucokinase impairs the interaction of glucokinase and glucokinase regulatory protein and regulates glucose metabolism.
    Futamura M; Hosaka H; Kadotani A; Shimazaki H; Sasaki K; Ohyama S; Nishimura T; Eiki J; Nagata Y
    J Biol Chem; 2006 Dec; 281(49):37668-74. PubMed ID: 17028192
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Defect in glucokinase translocation in Zucker diabetic fatty rats.
    Fujimoto Y; Donahue EP; Shiota M
    Am J Physiol Endocrinol Metab; 2004 Sep; 287(3):E414-23. PubMed ID: 15138155
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Glucotoxicity targets hepatic glucokinase in Zucker diabetic fatty rats, a model of type 2 diabetes associated with obesity.
    Ueta K; O'Brien TP; McCoy GA; Kim K; Healey EC; Farmer TD; Donahue EP; Condren AB; Printz RL; Shiota M
    Am J Physiol Endocrinol Metab; 2014 Jun; 306(11):E1225-38. PubMed ID: 24714398
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stimulation of hepatocyte glucose metabolism by novel small molecule glucokinase activators.
    Brocklehurst KJ; Payne VA; Davies RA; Carroll D; Vertigan HL; Wightman HJ; Aiston S; Waddell ID; Leighton B; Coghlan MP; Agius L
    Diabetes; 2004 Mar; 53(3):535-41. PubMed ID: 14988235
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insulin-receptor substrate-2 (irs-2) is required for maintaining glucokinase and glucokinase regulatory protein expression in mouse liver.
    Roncero I; Alvarez E; Acosta C; Sanz C; Barrio P; Hurtado-Carneiro V; Burks D; Blázquez E
    PLoS One; 2013; 8(4):e58797. PubMed ID: 23560040
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cellular characterisation of the GCKR P446L variant associated with type 2 diabetes risk.
    Rees MG; Wincovitch S; Schultz J; Waterstradt R; Beer NL; Baltrusch S; Collins FS; Gloyn AL
    Diabetologia; 2012 Jan; 55(1):114-22. PubMed ID: 22038520
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of the regulatory protein of glucokinase in the glucose sensory mechanism of the hepatocyte.
    de la Iglesia N; Mukhtar M; Seoane J; Guinovart JJ; Agius L
    J Biol Chem; 2000 Apr; 275(14):10597-603. PubMed ID: 10744755
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: a sequestration mechanism in metabolic regulation.
    Farrelly D; Brown KS; Tieman A; Ren J; Lira SA; Hagan D; Gregg R; Mookhtiar KA; Hariharan N
    Proc Natl Acad Sci U S A; 1999 Dec; 96(25):14511-6. PubMed ID: 10588736
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors.
    Lloyd DJ; St Jean DJ; Kurzeja RJ; Wahl RC; Michelsen K; Cupples R; Chen M; Wu J; Sivits G; Helmering J; Komorowski R; Ashton KS; Pennington LD; Fotsch C; Vazir M; Chen K; Chmait S; Zhang J; Liu L; Norman MH; Andrews KL; Bartberger MD; Van G; Galbreath EJ; Vonderfecht SL; Wang M; Jordan SR; Véniant MM; Hale C
    Nature; 2013 Dec; 504(7480):437-40. PubMed ID: 24226772
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting hepatic glucokinase in type 2 diabetes: weighing the benefits and risks.
    Agius L
    Diabetes; 2009 Jan; 58(1):18-20. PubMed ID: 19114725
    [No Abstract]   [Full Text] [Related]  

  • 17. Glucose-6-phosphatase overexpression lowers glucose 6-phosphate and inhibits glycogen synthesis and glycolysis in hepatocytes without affecting glucokinase translocation. Evidence against feedback inhibition of glucokinase.
    Aiston S; Trinh KY; Lange AJ; Newgard CB; Agius L
    J Biol Chem; 1999 Aug; 274(35):24559-66. PubMed ID: 10455119
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Treatment of type 2 diabetes by adenoviral-mediated overexpression of the glucokinase regulatory protein.
    Slosberg ED; Desai UJ; Fanelli B; St Denny I; Connelly S; Kaleko M; Boettcher BR; Caplan SL
    Diabetes; 2001 Aug; 50(8):1813-20. PubMed ID: 11473043
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver.
    Beer NL; Tribble ND; McCulloch LJ; Roos C; Johnson PR; Orho-Melander M; Gloyn AL
    Hum Mol Genet; 2009 Nov; 18(21):4081-8. PubMed ID: 19643913
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glucokinase regulatory protein is essential for the proper subcellular localisation of liver glucokinase.
    de la Iglesia N; Veiga-da-Cunha M; Van Schaftingen E; Guinovart JJ; Ferrer JC
    FEBS Lett; 1999 Aug; 456(2):332-8. PubMed ID: 10456334
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.