These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

307 related articles for article (PubMed ID: 17189273)

  • 1. Genetically altered expression of spermidine/spermine N1-acetyltransferase affects fat metabolism in mice via acetyl-CoA.
    Jell J; Merali S; Hensen ML; Mazurchuk R; Spernyak JA; Diegelman P; Kisiel ND; Barrero C; Deeb KK; Alhonen L; Patel MS; Porter CW
    J Biol Chem; 2007 Mar; 282(11):8404-13. PubMed ID: 17189273
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modulation of polyamine metabolic flux in adipose tissue alters the accumulation of body fat by affecting glucose homeostasis.
    Liu C; Perez-Leal O; Barrero C; Zahedi K; Soleimani M; Porter C; Merali S
    Amino Acids; 2014 Mar; 46(3):701-15. PubMed ID: 23881108
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activated polyamine catabolism depletes acetyl-CoA pools and suppresses prostate tumor growth in TRAMP mice.
    Kee K; Foster BA; Merali S; Kramer DL; Hensen ML; Diegelman P; Kisiel N; Vujcic S; Mazurchuk RV; Porter CW
    J Biol Chem; 2004 Sep; 279(38):40076-83. PubMed ID: 15252047
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mice with targeted disruption of spermidine/spermine N1-acetyltransferase gene maintain nearly normal tissue polyamine homeostasis but show signs of insulin resistance upon aging.
    Niiranen K; Keinänen TA; Pirinen E; Heikkinen S; Tusa M; Fatrai S; Suppola S; Pietilä M; Uimari A; Laakso M; Alhonen L; Jänne J
    J Cell Mol Med; 2006; 10(4):933-45. PubMed ID: 17125596
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potent modulation of intestinal tumorigenesis in Apcmin/+ mice by the polyamine catabolic enzyme spermidine/spermine N1-acetyltransferase.
    Tucker JM; Murphy JT; Kisiel N; Diegelman P; Barbour KW; Davis C; Medda M; Alhonen L; Jänne J; Kramer DL; Porter CW; Berger FG
    Cancer Res; 2005 Jun; 65(12):5390-8. PubMed ID: 15958588
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transgenic mice with activated polyamine catabolism due to overexpression of spermidine/spermine N1-acetyltransferase show enhanced sensitivity to the polyamine analog, N1, N11-diethylnorspermine.
    Alhonen L; Pietilä M; Halmekytö M; Kramer DL; Jänne J; Porter CW
    Mol Pharmacol; 1999 Apr; 55(4):693-8. PubMed ID: 10101027
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Spermidine/spermine-N(1)-acetyltransferase: a key metabolic regulator.
    Pegg AE
    Am J Physiol Endocrinol Metab; 2008 Jun; 294(6):E995-1010. PubMed ID: 18349109
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of spermidine/spermine N1-acetyltransferase by intracellular polyamine pools. Evidence for a functional role in polyamine homeostasis.
    Shappell NW; Fogel-Petrovic MF; Porter CW
    FEBS Lett; 1993 Apr; 321(2-3):179-83. PubMed ID: 8477847
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of polyamine catabolism profoundly alters tissue polyamine pools and affects hair growth and female fertility in transgenic mice overexpressing spermidine/spermine N1-acetyltransferase.
    Pietilä M; Alhonen L; Halmekytö M; Kanter P; Jänne J; Porter CW
    J Biol Chem; 1997 Jul; 272(30):18746-51. PubMed ID: 9228047
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Major increases in spermidine/spermine-N1-acetyltransferase activity by spermine analogues and their relationship to polyamine depletion and growth inhibition in L1210 cells.
    Libby PR; Henderson M; Bergeron RJ; Porter CW
    Cancer Res; 1989 Nov; 49(22):6226-31. PubMed ID: 2804970
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metabolic and antiproliferative consequences of activated polyamine catabolism in LNCaP prostate carcinoma cells.
    Kee K; Vujcic S; Merali S; Diegelman P; Kisiel N; Powell CT; Kramer DL; Porter CW
    J Biol Chem; 2004 Jun; 279(26):27050-8. PubMed ID: 15096507
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue.
    Suppola S; Pietilä M; Parkkinen JJ; Korhonen VP; Alhonen L; Halmekytö M; Porter CW; Jänne J
    Biochem J; 1999 Mar; 338 ( Pt 2)(Pt 2):311-6. PubMed ID: 10024505
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Concurrent overexpression of ornithine decarboxylase and spermidine/spermine N(1)-acetyltransferase further accelerates the catabolism of hepatic polyamines in transgenic mice.
    Suppola S; Heikkinen S; Parkkinen JJ; Uusi-Oukari M; Korhonen VP; Keinänen T; Alhonen L; Jänne J
    Biochem J; 2001 Sep; 358(Pt 2):343-8. PubMed ID: 11513732
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target.
    Bewley MC; Graziano V; Jiang J; Matz E; Studier FW; Pegg AE; Coleman CS; Flanagan JM
    Proc Natl Acad Sci U S A; 2006 Feb; 103(7):2063-8. PubMed ID: 16455797
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Polyamine acetylation modulates polyamine metabolic flux, a prelude to broader metabolic consequences.
    Kramer DL; Diegelman P; Jell J; Vujcic S; Merali S; Porter CW
    J Biol Chem; 2008 Feb; 283(7):4241-51. PubMed ID: 18089555
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of conditional overexpression of spermidine/spermine N1-acetyltransferase on polyamine pool dynamics, cell growth, and sensitivity to polyamine analogs.
    Vujcic S; Halmekyto M; Diegelman P; Gan G; Kramer DL; Janne J; Porter CW
    J Biol Chem; 2000 Dec; 275(49):38319-28. PubMed ID: 10978316
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metabolism of acetyl derivatives of polyamines in cultured polyamine-deficient rat hepatoma cells.
    Mamont PS; Seiler N; Siat M; Joder-Ohlenbusch AM; Knödgen B
    Med Biol; 1981 Dec; 59(5-6):347-53. PubMed ID: 6803078
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Polyamine and polyamine analog regulation of spermidine/spermine N1-acetyltransferase in MALME-3M human melanoma cells.
    Fogel-Petrovic M; Shappell NW; Bergeron RJ; Porter CW
    J Biol Chem; 1993 Sep; 268(25):19118-25. PubMed ID: 8360194
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induction of spermidine/spermine N1-acetyltransferase in rat tissues by polyamines.
    Pegg AE; Erwin BG
    Biochem J; 1985 Oct; 231(2):285-9. PubMed ID: 4062898
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Correlation of polyamine and growth responses to N1,N11-diethylnorspermine in primary fetal fibroblasts derived from transgenic mice overexpressing spermidine/spermine N1-acetyltransferase.
    Alhonen L; Karppinen A; Uusi-Oukari M; Vujcic S; Korhonen VP; Halmekytö M; Kramer DL; Hines R; Jänne J; Porter CW
    J Biol Chem; 1998 Jan; 273(4):1964-9. PubMed ID: 9442032
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.