These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

431 related articles for article (PubMed ID: 17190598)

  • 1. ATAXIN-1 interacts with the repressor Capicua in its native complex to cause SCA1 neuropathology.
    Lam YC; Bowman AB; Jafar-Nejad P; Lim J; Richman R; Fryer JD; Hyun ED; Duvick LA; Orr HT; Botas J; Zoghbi HY
    Cell; 2006 Dec; 127(7):1335-47. PubMed ID: 17190598
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Duplication of Atxn1l suppresses SCA1 neuropathology by decreasing incorporation of polyglutamine-expanded ataxin-1 into native complexes.
    Bowman AB; Lam YC; Jafar-Nejad P; Chen HK; Richman R; Samaco RC; Fryer JD; Kahle JJ; Orr HT; Zoghbi HY
    Nat Genet; 2007 Mar; 39(3):373-9. PubMed ID: 17322884
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hosting neurotoxicity in polyglutamine disease.
    Liu N; Bonini NM
    Cell; 2006 Dec; 127(7):1299-300. PubMed ID: 17190592
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Boat, an AXH domain protein, suppresses the cytotoxicity of mutant ataxin-1.
    Mizutani A; Wang L; Rajan H; Vig PJ; Alaynick WA; Thaler JP; Tsai CC
    EMBO J; 2005 Sep; 24(18):3339-51. PubMed ID: 16121196
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Exercise and genetic rescue of SCA1 via the transcriptional repressor Capicua.
    Fryer JD; Yu P; Kang H; Mandel-Brehm C; Carter AN; Crespo-Barreto J; Gao Y; Flora A; Shaw C; Orr HT; Zoghbi HY
    Science; 2011 Nov; 334(6056):690-3. PubMed ID: 22053053
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1.
    Lim J; Crespo-Barreto J; Jafar-Nejad P; Bowman AB; Richman R; Hill DE; Orr HT; Zoghbi HY
    Nature; 2008 Apr; 452(7188):713-8. PubMed ID: 18337722
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SUMO-1 interacts with mutant ataxin-1 and colocalizes to its aggregates in Purkinje cells of SCA1 transgenic mice.
    Kang S; Hong S
    Arch Ital Biol; 2010 Dec; 148(4):351-63. PubMed ID: 21308649
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of genes that modify ataxin-1-induced neurodegeneration.
    Fernandez-Funez P; Nino-Rosales ML; de Gouyon B; She WC; Luchak JM; Martinez P; Turiegano E; Benito J; Capovilla M; Skinner PJ; McCall A; Canal I; Orr HT; Zoghbi HY; Botas J
    Nature; 2000 Nov; 408(6808):101-6. PubMed ID: 11081516
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis.
    Crespo-Barreto J; Fryer JD; Shaw CA; Orr HT; Zoghbi HY
    PLoS Genet; 2010 Jul; 6(7):e1001021. PubMed ID: 20628574
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural basis of the phosphorylation dependent complex formation of neurodegenerative disease protein Ataxin-1 and RBM17.
    Kim E; Lee Y; Choi S; Song JJ
    Biochem Biophys Res Commun; 2014 Jul; 449(4):399-404. PubMed ID: 24858692
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural basis of protein complex formation and reconfiguration by polyglutamine disease protein Ataxin-1 and Capicua.
    Kim E; Lu HC; Zoghbi HY; Song JJ
    Genes Dev; 2013 Mar; 27(6):590-5. PubMed ID: 23512657
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The cerebellar leucine-rich acidic nuclear protein interacts with ataxin-1.
    Matilla A; Koshy BT; Cummings CJ; Isobe T; Orr HT; Zoghbi HY
    Nature; 1997 Oct; 389(6654):974-8. PubMed ID: 9353121
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RORalpha-mediated Purkinje cell development determines disease severity in adult SCA1 mice.
    Serra HG; Duvick L; Zu T; Carlson K; Stevens S; Jorgensen N; Lysholm A; Burright E; Zoghbi HY; Clark HB; Andresen JM; Orr HT
    Cell; 2006 Nov; 127(4):697-708. PubMed ID: 17110330
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RNA association and nucleocytoplasmic shuttling by ataxin-1.
    Irwin S; Vandelft M; Pinchev D; Howell JL; Graczyk J; Orr HT; Truant R
    J Cell Sci; 2005 Jan; 118(Pt 1):233-42. PubMed ID: 15615787
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The ins and outs of a polyglutamine neurodegenerative disease: spinocerebellar ataxia type 1 (SCA1).
    Orr HT
    Neurobiol Dis; 2000 Jun; 7(3):129-34. PubMed ID: 10860780
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SCA1-phosphorylation, a regulator of Ataxin-1 function and pathogenesis.
    Orr HT
    Prog Neurobiol; 2012 Dec; 99(3):179-85. PubMed ID: 22531670
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.
    Rousseaux MWC; Tschumperlin T; Lu HC; Lackey EP; Bondar VV; Wan YW; Tan Q; Adamski CJ; Friedrich J; Twaroski K; Chen W; Tolar J; Henzler C; Sharma A; Bajić A; Lin T; Duvick L; Liu Z; Sillitoe RV; Zoghbi HY; Orr HT
    Neuron; 2018 Mar; 97(6):1235-1243.e5. PubMed ID: 29526553
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An out-of-frame overlapping reading frame in the ataxin-1 coding sequence encodes a novel ataxin-1 interacting protein.
    Bergeron D; Lapointe C; Bissonnette C; Tremblay G; Motard J; Roucou X
    J Biol Chem; 2013 Jul; 288(30):21824-35. PubMed ID: 23760502
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1.
    Lasagna-Reeves CA; Rousseaux MW; Guerrero-Muñoz MJ; Park J; Jafar-Nejad P; Richman R; Lu N; Sengupta U; Litvinchuk A; Orr HT; Kayed R; Zoghbi HY
    Elife; 2015 May; 4():. PubMed ID: 25988806
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel function of Ataxin-1 in the modulation of PP2A activity is dysregulated in the spinocerebellar ataxia type 1.
    Sánchez I; Piñol P; Corral-Juan M; Pandolfo M; Matilla-Dueñas A
    Hum Mol Genet; 2013 Sep; 22(17):3425-37. PubMed ID: 23630944
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.