These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 17196984)

  • 1. Crystal structures reveal an induced-fit binding of a substrate-like Aza-peptide epoxide to SARS coronavirus main peptidase.
    Lee TW; Cherney MM; Liu J; James KE; Powers JC; Eltis LD; James MN
    J Mol Biol; 2007 Feb; 366(3):916-32. PubMed ID: 17196984
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structures of the main peptidase from the SARS coronavirus inhibited by a substrate-like aza-peptide epoxide.
    Lee TW; Cherney MM; Huitema C; Liu J; James KE; Powers JC; Eltis LD; James MN
    J Mol Biol; 2005 Nov; 353(5):1137-51. PubMed ID: 16219322
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanism for controlling the monomer-dimer conversion of SARS coronavirus main protease.
    Wu CG; Cheng SC; Chen SC; Li JY; Fang YH; Chen YH; Chou CY
    Acta Crystallogr D Biol Crystallogr; 2013 May; 69(Pt 5):747-55. PubMed ID: 23633583
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease.
    Zhu L; George S; Schmidt MF; Al-Gharabli SI; Rademann J; Hilgenfeld R
    Antiviral Res; 2011 Nov; 92(2):204-12. PubMed ID: 21854807
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Substrate specificity profiling and identification of a new class of inhibitor for the major protease of the SARS coronavirus.
    Goetz DH; Choe Y; Hansell E; Chen YT; McDowell M; Jonsson CB; Roush WR; McKerrow J; Craik CS
    Biochemistry; 2007 Jul; 46(30):8744-52. PubMed ID: 17605471
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protein structural heterogeneity: A hypothesis for the basis of proteolytic recognition by the main protease of SARS-CoV and SARS-CoV-2.
    Behnam MAM
    Biochimie; 2021 Mar; 182():177-184. PubMed ID: 33484784
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Production of authentic SARS-CoV M(pro) with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction.
    Xue X; Yang H; Shen W; Zhao Q; Li J; Yang K; Chen C; Jin Y; Bartlam M; Rao Z
    J Mol Biol; 2007 Feb; 366(3):965-75. PubMed ID: 17189639
    [TBL] [Abstract][Full Text] [Related]  

  • 8. pH-dependent conformational flexibility of the SARS-CoV main proteinase (M(pro)) dimer: molecular dynamics simulations and multiple X-ray structure analyses.
    Tan J; Verschueren KH; Anand K; Shen J; Yang M; Xu Y; Rao Z; Bigalke J; Heisen B; Mesters JR; Chen K; Shen X; Jiang H; Hilgenfeld R
    J Mol Biol; 2005 Nov; 354(1):25-40. PubMed ID: 16242152
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease.
    Lu IL; Mahindroo N; Liang PH; Peng YH; Kuo CJ; Tsai KC; Hsieh HP; Chao YS; Wu SY
    J Med Chem; 2006 Aug; 49(17):5154-61. PubMed ID: 16913704
    [TBL] [Abstract][Full Text] [Related]  

  • 10. C-terminal domain of SARS-CoV main protease can form a 3D domain-swapped dimer.
    Zhong N; Zhang S; Xue F; Kang X; Zou P; Chen J; Liang C; Rao Z; Jin C; Lou Z; Xia B
    Protein Sci; 2009 Apr; 18(4):839-44. PubMed ID: 19319935
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor.
    Yang H; Yang M; Ding Y; Liu Y; Lou Z; Zhou Z; Sun L; Mo L; Ye S; Pang H; Gao GF; Anand K; Bartlam M; Hilgenfeld R; Rao Z
    Proc Natl Acad Sci U S A; 2003 Nov; 100(23):13190-5. PubMed ID: 14585926
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structures of the Middle East respiratory syndrome coronavirus 3C-like protease reveal insights into substrate specificity.
    Needle D; Lountos GT; Waugh DS
    Acta Crystallogr D Biol Crystallogr; 2015 May; 71(Pt 5):1102-11. PubMed ID: 25945576
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the SARS-CoV 3C-like peptidase.
    Yin J; Niu C; Cherney MM; Zhang J; Huitema C; Eltis LD; Vederas JC; James MN
    J Mol Biol; 2007 Aug; 371(4):1060-74. PubMed ID: 17599357
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Quaternary structure of the severe acute respiratory syndrome (SARS) coronavirus main protease.
    Chou CY; Chang HC; Hsu WC; Lin TZ; Lin CH; Chang GG
    Biochemistry; 2004 Nov; 43(47):14958-70. PubMed ID: 15554703
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Insights into cleavage specificity from the crystal structure of foot-and-mouth disease virus 3C protease complexed with a peptide substrate.
    Zunszain PA; Knox SR; Sweeney TR; Yang J; Roqué-Rosell N; Belsham GJ; Leatherbarrow RJ; Curry S
    J Mol Biol; 2010 Jan; 395(2):375-89. PubMed ID: 19883658
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular docking identifies the binding of 3-chloropyridine moieties specifically to the S1 pocket of SARS-CoV Mpro.
    Niu C; Yin J; Zhang J; Vederas JC; James MN
    Bioorg Med Chem; 2008 Jan; 16(1):293-302. PubMed ID: 17931870
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Severe acute respiratory syndrome coronavirus 3C-like proteinase N terminus is indispensable for proteolytic activity but not for enzyme dimerization. Biochemical and thermodynamic investigation in conjunction with molecular dynamics simulations.
    Chen S; Chen L; Tan J; Chen J; Du L; Sun T; Shen J; Chen K; Jiang H; Shen X
    J Biol Chem; 2005 Jan; 280(1):164-73. PubMed ID: 15507456
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Insight into the activity of SARS main protease: Molecular dynamics study of dimeric and monomeric form of enzyme.
    Zheng K; Ma G; Zhou J; Zen M; Zhao W; Jiang Y; Yu Q; Feng J
    Proteins; 2007 Feb; 66(2):467-79. PubMed ID: 17083088
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation and maturation of SARS-CoV main protease.
    Xia B; Kang X
    Protein Cell; 2011 Apr; 2(4):282-90. PubMed ID: 21533772
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural Basis of the Main Proteases of Coronavirus Bound to Drug Candidate PF-07321332.
    Li J; Lin C; Zhou X; Zhong F; Zeng P; Yang Y; Zhang Y; Yu B; Fan X; McCormick PJ; Fu R; Fu Y; Jiang H; Zhang J
    J Virol; 2022 Apr; 96(8):e0201321. PubMed ID: 35389231
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.