These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 17206380)

  • 21. Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.
    Ben-Sahra I; Howell JJ; Asara JM; Manning BD
    Science; 2013 Mar; 339(6125):1323-8. PubMed ID: 23429703
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Nucleotide ligands protect the inter-domain regions of the multifunctional polypeptide CAD against limited proteolysis, and also stabilize the thermolabile part-reactions of the carbamoyl-phosphate synthase II domains within the CAD polypeptide.
    Carrey EA
    Biochem J; 1986 Jun; 236(2):327-35. PubMed ID: 3638965
    [TBL] [Abstract][Full Text] [Related]  

  • 23. carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (cad) regulates Notch signaling and vascular development in zebrafish.
    Coxam B; Neyt C; Grassini DR; Le Guen L; Smith KA; Schulte-Merker S; Hogan BM
    Dev Dyn; 2015 Jan; 244(1):1-9. PubMed ID: 25294789
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Appearance of CAD activity, the rate-limiting enzyme for pyrimidine biosynthesis, as B cells progress into and through the G1 stage of the cell cycle.
    Morford G; Davidson JN; Snow EC
    Cell Immunol; 1994 Oct; 158(1):96-104. PubMed ID: 7916269
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Molecular interaction of the first 3 enzymes of the de novo pyrimidine biosynthetic pathway of Trypanosoma cruzi.
    Nara T; Hashimoto M; Hirawake H; Liao CW; Fukai Y; Suzuki S; Tsubouchi A; Morales J; Takamiya S; Fujimura T; Taka H; Mineki R; Fan CK; Inaoka DK; Inoue M; Tanaka A; Harada S; Kita K; Aoki T
    Biochem Biophys Res Commun; 2012 Feb; 418(1):140-3. PubMed ID: 22245425
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Intracellular location of the multidomain protein CAD in mammalian cells.
    Chaparian MG; Evans DR
    FASEB J; 1988 Nov; 2(14):2982-9. PubMed ID: 2903106
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Mapping of catalytic domains and phosphorylation sites in the multifunctional pyrimidine-biosynthetic protein CAD.
    Carrey EA; Hardie DG
    Eur J Biochem; 1988 Feb; 171(3):583-8. PubMed ID: 3345746
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis.
    Rabinovich S; Adler L; Yizhak K; Sarver A; Silberman A; Agron S; Stettner N; Sun Q; Brandis A; Helbling D; Korman S; Itzkovitz S; Dimmock D; Ulitsky I; Nagamani SC; Ruppin E; Erez A
    Nature; 2015 Nov; 527(7578):379-383. PubMed ID: 26560030
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis.
    Moreno-Morcillo M; Grande-García A; Ruiz-Ramos A; Del Caño-Ochoa F; Boskovic J; Ramón-Maiques S
    Structure; 2017 Jun; 25(6):912-923.e5. PubMed ID: 28552578
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A protonated histidine residue in a phosphorylation site for cyclic AMP-dependent protein kinase. Comparison of a synthetic peptide with the exposed linking region in the multienzyme polypeptide CAD.
    Carrey EA
    Biochem J; 1992 Nov; 287 ( Pt 3)(Pt 3):791-5. PubMed ID: 1359877
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Estrogen receptor/Sp1 complexes are required for induction of cad gene expression by 17beta-estradiol in breast cancer cells.
    Khan S; Abdelrahim M; Samudio I; Safe S
    Endocrinology; 2003 Jun; 144(6):2325-35. PubMed ID: 12746293
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Glutamine-dependent carbamoyl-phosphate synthetase and control of pyrimidine biosynthesis in the parasitic helminth Schistosoma mansoni.
    Aoki T; Oya H
    Comp Biochem Physiol B; 1979; 63(4):511-5. PubMed ID: 45544
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Allosteric regulation and substrate channeling in multifunctional pyrimidine biosynthetic complexes: analysis of isolated domains and yeast-mammalian chimeric proteins.
    Serre V; Guy H; Liu X; Penverne B; Hervé G; Evans D
    J Mol Biol; 1998 Aug; 281(2):363-77. PubMed ID: 9698553
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Adenovirus preterminal protein binds to the CAD enzyme at active sites of viral DNA replication on the nuclear matrix.
    Angeletti PC; Engler JA
    J Virol; 1998 Apr; 72(4):2896-904. PubMed ID: 9525610
    [TBL] [Abstract][Full Text] [Related]  

  • 35. De novo synthesis of pyrimidine nucleotides; emerging interfaces with signal transduction pathways.
    Huang M; Graves LM
    Cell Mol Life Sci; 2003 Feb; 60(2):321-36. PubMed ID: 12678497
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Identification of the binding site for the allosteric inactivator UTP in mammalian CPS II.
    Zhu LM; Carrey EA
    Biochem Soc Trans; 1995 Nov; 23(4):620S. PubMed ID: 8654805
    [No Abstract]   [Full Text] [Related]  

  • 37. Catalytic synergy in the multifunctional protein that initiates pyrimidine biosynthesis in Syrian hamster cells.
    Mally MI; Grayson DR; Evans DR
    J Biol Chem; 1980 Dec; 255(23):11372-80. PubMed ID: 6108322
    [No Abstract]   [Full Text] [Related]  

  • 38. Caspase-dependent cleavage of carbamoyl phosphate synthetase II during apoptosis.
    Huang M; Kozlowski P; Collins M; Wang Y; Haystead TA; Graves LM
    Mol Pharmacol; 2002 Mar; 61(3):569-77. PubMed ID: 11854437
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Deciphering CAD: Structure and function of a mega-enzymatic pyrimidine factory in health and disease.
    Del Caño-Ochoa F; Ramón-Maiques S
    Protein Sci; 2021 Oct; 30(10):1995-2008. PubMed ID: 34288185
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Prostaglandin E2 activates cAMP response element-binding protein in glioma cells via a signaling pathway involving PKA-dependent inhibition of ERK.
    Bidwell P; Joh K; Leaver HA; Rizzo MT
    Prostaglandins Other Lipid Mediat; 2010 Feb; 91(1-2):18-29. PubMed ID: 20015475
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.