BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

104 related articles for article (PubMed ID: 17208201)

  • 1. Aggregate-centered redistribution of proteins by mutant huntingtin.
    Swayne LA; Braun JE
    Biochem Biophys Res Commun; 2007 Mar; 354(1):39-44. PubMed ID: 17208201
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity.
    Jana NR; Tanaka M; Wang Gh; Nukina N
    Hum Mol Genet; 2000 Aug; 9(13):2009-18. PubMed ID: 10942430
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sensitive biochemical aggregate detection reveals aggregation onset before symptom development in cellular and murine models of Huntington's disease.
    Weiss A; Klein C; Woodman B; Sathasivam K; Bibel M; Régulier E; Bates GP; Paganetti P
    J Neurochem; 2008 Feb; 104(3):846-58. PubMed ID: 17986219
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heat shock protein 70 alters the endosome-lysosomal localization of huntingtin.
    Kang BS; Ahn JY; Kim MK; Kim HJ; Kang L; Lim HC; Park KS; Lee JS; Seo JS; Cha CI; Kim SU; Park YJ; Kim M
    Exp Mol Med; 2007 Feb; 39(1):38-46. PubMed ID: 17334227
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutant huntingtin forms in vivo complexes with distinct context-dependent conformations of the polyglutamine segment.
    Persichetti F; Trettel F; Huang CC; Fraefel C; Timmers HT; Gusella JF; MacDonald ME
    Neurobiol Dis; 1999 Oct; 6(5):364-75. PubMed ID: 10527804
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tissue transglutaminase selectively modifies proteins associated with truncated mutant huntingtin in intact cells.
    Chun W; Lesort M; Tucholski J; Faber PW; MacDonald ME; Ross CA; Johnson GV
    Neurobiol Dis; 2001 Jun; 8(3):391-404. PubMed ID: 11442349
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways.
    Velier J; Kim M; Schwarz C; Kim TW; Sapp E; Chase K; Aronin N; DiFiglia M
    Exp Neurol; 1998 Jul; 152(1):34-40. PubMed ID: 9682010
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant huntingtin expression in clonal striatal cells: dissociation of inclusion formation and neuronal survival by caspase inhibition.
    Kim M; Lee HS; LaForet G; McIntyre C; Martin EJ; Chang P; Kim TW; Williams M; Reddy PH; Tagle D; Boyce FM; Won L; Heller A; Aronin N; DiFiglia M
    J Neurosci; 1999 Feb; 19(3):964-73. PubMed ID: 9920660
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of neuron-specific huntingtin aggregates in human huntingtin knock-in mice.
    Sawada H; Ishiguro H; Nishii K; Yamada K; Tsuchida K; Takahashi H; Goto J; Kanazawa I; Nagatsu T
    Neurosci Res; 2007 Apr; 57(4):559-73. PubMed ID: 17335925
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction.
    Goswami A; Dikshit P; Mishra A; Mulherkar S; Nukina N; Jana NR
    Biochem Biophys Res Commun; 2006 Mar; 342(1):184-90. PubMed ID: 16472774
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Purification of neuronal inclusions of patients with Huntington's disease reveals a broad range of N-terminal fragments of expanded huntingtin and insoluble polymers.
    Hoffner G; Island ML; Djian P
    J Neurochem; 2005 Oct; 95(1):125-36. PubMed ID: 16181417
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reversal of a full-length mutant huntingtin neuronal cell phenotype by chemical inhibitors of polyglutamine-mediated aggregation.
    Wang J; Gines S; MacDonald ME; Gusella JF
    BMC Neurosci; 2005 Jan; 6():1. PubMed ID: 15649316
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antisense downregulation of mutant huntingtin in a cell model.
    Hasholt L; Abell K; Nørremølle A; Nellemann C; Fenger K; Sørensen SA
    J Gene Med; 2003 Jun; 5(6):528-38. PubMed ID: 12797118
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Huntingtin fragments that aggregate go their separate ways.
    DiFiglia M
    Mol Cell; 2002 Aug; 10(2):224-5. PubMed ID: 12191468
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inducing huntingtin inclusion formation in primary neuronal cell culture and in vivo by high-capacity adenoviral vectors expressing truncated and full-length huntingtin with polyglutamine expansion.
    Huang B; Schiefer J; Sass C; Kosinski CM; Kochanek S
    J Gene Med; 2008 Mar; 10(3):269-79. PubMed ID: 18067195
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 14-3-3zeta is indispensable for aggregate formation of polyglutamine-expanded huntingtin protein.
    Omi K; Hachiya NS; Tanaka M; Tokunaga K; Kaneko K
    Neurosci Lett; 2008 Jan; 431(1):45-50. PubMed ID: 18078716
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Progressive and selective striatal degeneration in primary neuronal cultures using lentiviral vector coding for a mutant huntingtin fragment.
    Zala D; Benchoua A; Brouillet E; Perrin V; Gaillard MC; Zurn AD; Aebischer P; Déglon N
    Neurobiol Dis; 2005 Dec; 20(3):785-98. PubMed ID: 16006135
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Huntingtin processing in pathogenesis of Huntington disease.
    Qin ZH; Gu ZL
    Acta Pharmacol Sin; 2004 Oct; 25(10):1243-9. PubMed ID: 15456523
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inactivation of Apaf1 reduces the formation of mutant huntingtin-dependent aggregates and cell death.
    Sancho M; Herrera AE; Orzáez M; Pérez-Payá E
    Neuroscience; 2014 Mar; 262():83-91. PubMed ID: 24412373
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chaperone suppression of cellular toxicity of huntingtin is independent of polyglutamine aggregation.
    Zhou H; Li SH; Li XJ
    J Biol Chem; 2001 Dec; 276(51):48417-24. PubMed ID: 11606565
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.