These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

346 related articles for article (PubMed ID: 17210712)

  • 1. Pegylated recombinant human arginase (rhArg-peg5,000mw) inhibits the in vitro and in vivo proliferation of human hepatocellular carcinoma through arginine depletion.
    Cheng PN; Lam TL; Lam WM; Tsui SM; Cheng AW; Lo WH; Leung YC
    Cancer Res; 2007 Jan; 67(1):309-17. PubMed ID: 17210712
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Recombinant human arginase inhibits proliferation of human hepatocellular carcinoma by inducing cell cycle arrest.
    Lam TL; Wong GK; Chong HC; Cheng PN; Choi SC; Chow TL; Kwok SY; Poon RT; Wheatley DN; Lo WH; Leung YC
    Cancer Lett; 2009 May; 277(1):91-100. PubMed ID: 19138817
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A phase II clinical study on the efficacy and predictive biomarker of pegylated recombinant arginase on hepatocellular carcinoma.
    Chan SL; Cheng PNM; Liu AM; Chan LL; Li L; Chu CM; Chong CCN; Lau YM; Yeo W; Ng KKC; Yu SCH; Mok TSK; Chan AWH
    Invest New Drugs; 2021 Oct; 39(5):1375-1382. PubMed ID: 33856599
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Combination of Arginine Deprivation and 5-Fluorouracil Improves Therapeutic Efficacy in Argininosuccinate Synthetase Negative Hepatocellular Carcinoma.
    Thongkum A; Wu C; Li YY; Wangpaichitr M; Navasumrit P; Parnlob V; Sricharunrat T; Bhudhisawasdi V; Ruchirawat M; Savaraj N
    Int J Mol Sci; 2017 Jun; 18(6):. PubMed ID: 28587170
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pegylated arginine deiminase (ADI-SS PEG20,000 mw) inhibits human melanomas and hepatocellular carcinomas in vitro and in vivo.
    Ensor CM; Holtsberg FW; Bomalaski JS; Clark MA
    Cancer Res; 2002 Oct; 62(19):5443-50. PubMed ID: 12359751
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Recombinant human arginase inhibits the in vitro and in vivo proliferation of human melanoma by inducing cell cycle arrest and apoptosis.
    Lam TL; Wong GK; Chow HY; Chong HC; Chow TL; Kwok SY; Cheng PN; Wheatley DN; Lo WH; Leung YC
    Pigment Cell Melanoma Res; 2011 Apr; 24(2):366-76. PubMed ID: 21029397
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pancreatic cancer cell lines deficient in argininosuccinate synthetase are sensitive to arginine deprivation by arginine deiminase.
    Bowles TL; Kim R; Galante J; Parsons CM; Virudachalam S; Kung HJ; Bold RJ
    Int J Cancer; 2008 Oct; 123(8):1950-5. PubMed ID: 18661517
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Renal cell carcinoma does not express argininosuccinate synthetase and is highly sensitive to arginine deprivation via arginine deiminase.
    Yoon CY; Shim YJ; Kim EH; Lee JH; Won NH; Kim JH; Park IS; Yoon DK; Min BH
    Int J Cancer; 2007 Feb; 120(4):897-905. PubMed ID: 17096330
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Deprivation of arginine by recombinant human arginase in prostate cancer cells.
    Hsueh EC; Knebel SM; Lo WH; Leung YC; Cheng PN; Hsueh CT
    J Hematol Oncol; 2012 Apr; 5():17. PubMed ID: 22546217
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes.
    Alexandrou C; Al-Aqbi SS; Higgins JA; Boyle W; Karmokar A; Andreadi C; Luo JL; Moore DA; Viskaduraki M; Blades M; Murray GI; Howells LM; Thomas A; Brown K; Cheng PN; Rufini A
    Sci Rep; 2018 Aug; 8(1):12096. PubMed ID: 30108309
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Arginine deprivation as a targeted therapy for cancer.
    Feun L; You M; Wu CJ; Kuo MT; Wangpaichitr M; Spector S; Savaraj N
    Curr Pharm Des; 2008; 14(11):1049-57. PubMed ID: 18473854
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeted cellular metabolism for cancer chemotherapy with recombinant arginine-degrading enzymes.
    Kuo MT; Savaraj N; Feun LG
    Oncotarget; 2010 Aug; 1(4):246-51. PubMed ID: 21152246
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction of arginosuccinate synthetase (ASS) expression affects the antiproliferative activity of arginine deiminase (ADI) in melanoma cells.
    Manca A; Sini MC; Izzo F; Ascierto PA; Tatangelo F; Botti G; Gentilcore G; Capone M; Mozzillo N; Rozzo C; Cossu A; Tanda F; Palmieri G
    Oncol Rep; 2011 Jun; 25(6):1495-502. PubMed ID: 21424129
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Down-regulation of argininosuccinate synthetase is associated with cisplatin resistance in hepatocellular carcinoma cell lines: implications for PEGylated arginine deiminase combination therapy.
    McAlpine JA; Lu HT; Wu KC; Knowles SK; Thomson JA
    BMC Cancer; 2014 Aug; 14():621. PubMed ID: 25164070
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bioengineered arginase I increases caspase-3 expression of hepatocellular and pancreatic carcinoma cells despite induction of argininosuccinate synthetase-1.
    Glazer ES; Kaluarachchi WD; Massey KL; Zhu C; Curley SA
    Surgery; 2010 Aug; 148(2):310-8. PubMed ID: 20466402
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The arginine metabolome in acute lymphoblastic leukemia can be targeted by the pegylated-recombinant arginase I BCT-100.
    De Santo C; Booth S; Vardon A; Cousins A; Tubb V; Perry T; Noyvert B; Beggs A; Ng M; Halsey C; Kearns P; Cheng P; Mussai F
    Int J Cancer; 2018 Apr; 142(7):1490-1502. PubMed ID: 29168171
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mono-PEGylation of a Thermostable Arginine-Depleting Enzyme for the Treatment of Lung Cancer.
    Chung SF; Kim CF; Kwok SY; Tam SY; Chen YW; Chong HC; Leung SL; So PK; Wong KY; Leung YC; Lo WH
    Int J Mol Sci; 2020 Jun; 21(12):. PubMed ID: 32545874
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytotoxicity of human recombinant arginase I (Co)-PEG5000 in the presence of supplemental L-citrulline is dependent on decreased argininosuccinate synthetase expression in human cells.
    Agrawal V; Woo JH; Mauldin JP; Jo C; Stone EM; Georgiou G; Frankel AE
    Anticancer Drugs; 2012 Jan; 23(1):51-64. PubMed ID: 21955999
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cancer cell sensitivity to arginine deprivation in vitro is not determined by endogenous levels of arginine metabolic enzymes.
    Bobak YP; Vynnytska BO; Kurlishchuk YV; Sibirny AA; Stasyk OV
    Cell Biol Int; 2010 Nov; 34(11):1085-9. PubMed ID: 20653567
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pegylated arginine deiminase: a novel anticancer enzyme agent.
    Feun L; Savaraj N
    Expert Opin Investig Drugs; 2006 Jul; 15(7):815-22. PubMed ID: 16787144
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.