BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

250 related articles for article (PubMed ID: 17212810)

  • 41. Insight into the structural similarity between HIV protease and secreted aspartic protease-2 and binding mode analysis of HIV-Candida albicans inhibitors.
    Calugi C; Guarna A; Trabocchi A
    J Enzyme Inhib Med Chem; 2013 Oct; 28(5):936-43. PubMed ID: 22803674
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Assessment of FIV-C infection of cats as a function of treatment with the protease inhibitor, TL-3.
    de Rozières S; Swan CH; Sheeter DA; Clingerman KJ; Lin YC; Huitron-Resendiz S; Henriksen S; Torbett BE; Elder JH
    Retrovirology; 2004 Nov; 1():38. PubMed ID: 15555065
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Three-dimensional structures of HIV-1 and SIV protease product complexes.
    Rose RB; Craik CS; Douglas NL; Stroud RM
    Biochemistry; 1996 Oct; 35(39):12933-44. PubMed ID: 8841139
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Comparison of the substrate specificity of the human T-cell leukemia virus and human immunodeficiency virus proteinases.
    Tözsér J; Zahuczky G; Bagossi P; Louis JM; Copeland TD; Oroszlan S; Harrison RW; Weber IT
    Eur J Biochem; 2000 Oct; 267(20):6287-95. PubMed ID: 11012683
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Effectiveness of nonpeptide clinical inhibitor TMC-114 on HIV-1 protease with highly drug resistant mutations D30N, I50V, and L90M.
    Kovalevsky AY; Tie Y; Liu F; Boross PI; Wang YF; Leshchenko S; Ghosh AK; Harrison RW; Weber IT
    J Med Chem; 2006 Feb; 49(4):1379-87. PubMed ID: 16480273
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Mechanism of drug resistance revealed by the crystal structure of the unliganded HIV-1 protease with F53L mutation.
    Liu F; Kovalevsky AY; Louis JM; Boross PI; Wang YF; Harrison RW; Weber IT
    J Mol Biol; 2006 May; 358(5):1191-9. PubMed ID: 16569415
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Kinetic and modeling studies of subsites S4-S3' of Moloney murine leukemia virus protease.
    Menéndez-Arias L; Weber IT; Soss J; Harrison RW; Gotte D; Oroszlan S
    J Biol Chem; 1994 Jun; 269(24):16795-801. PubMed ID: 8207003
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Structural analysis of an HIV-1 protease I47A mutant resistant to the protease inhibitor lopinavir.
    Kagan RM; Shenderovich MD; Heseltine PN; Ramnarayan K
    Protein Sci; 2005 Jul; 14(7):1870-8. PubMed ID: 15937277
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114.
    Kovalevsky AY; Liu F; Leshchenko S; Ghosh AK; Louis JM; Harrison RW; Weber IT
    J Mol Biol; 2006 Oct; 363(1):161-73. PubMed ID: 16962136
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Effect of mutations on the dimer stability and the pH optimum of the human foamy virus protease.
    Sperka T; Boross P; Eizert H; Tözsér J; Bagossi P
    Protein Eng Des Sel; 2006 Aug; 19(8):369-75. PubMed ID: 16799151
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Molecular basis of HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with cyclic urea inhibitors.
    Ala PJ; Huston EE; Klabe RM; McCabe DD; Duke JL; Rizzo CJ; Korant BD; DeLoskey RJ; Lam PY; Hodge CN; Chang CH
    Biochemistry; 1997 Feb; 36(7):1573-80. PubMed ID: 9048541
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Systematic mutational analysis of the active-site threonine of HIV-1 proteinase: rethinking the "fireman's grip" hypothesis.
    Strisovsky K; Tessmer U; Langner J; Konvalinka J; Kräusslich HG
    Protein Sci; 2000 Sep; 9(9):1631-41. PubMed ID: 11045610
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Susceptibility of feline immunodeficiency virus/human immunodeficiency virus type 1 reverse transcriptase chimeras to non-nucleoside RT inhibitors.
    Auwerx J; Esnouf R; De Clercq E; Balzarini J
    Mol Pharmacol; 2004 Jan; 65(1):244-51. PubMed ID: 14722257
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Role of hydroxyl group and R/S configuration of isostere in binding properties of HIV-1 protease inhibitors.
    Petroková H; Dusková J; Dohnálek J; Skálová T; Vondrácková-Buchtelová E; Soucek M; Konvalinka J; Brynda J; Fábry M; Sedlácek J; Hasek J
    Eur J Biochem; 2004 Nov; 271(22):4451-61. PubMed ID: 15560786
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Crystal structures of complexes of a peptidic inhibitor with wild-type and two mutant HIV-1 proteases.
    Hong L; Treharne A; Hartsuck JA; Foundling S; Tang J
    Biochemistry; 1996 Aug; 35(33):10627-33. PubMed ID: 8718851
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Comparison of inhibitor binding in HIV-1 protease and in non-viral aspartic proteases: the role of the flap.
    Gustchina A; Weber IT
    FEBS Lett; 1990 Aug; 269(1):269-72. PubMed ID: 2201571
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Structural and kinetic analysis of drug resistant mutants of HIV-1 protease.
    Mahalingam B; Louis JM; Reed CC; Adomat JM; Krouse J; Wang YF; Harrison RW; Weber IT
    Eur J Biochem; 1999 Jul; 263(1):238-45. PubMed ID: 10429209
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Cyclic urea amides: HIV-1 protease inhibitors with low nanomolar potency against both wild type and protease inhibitor resistant mutants of HIV.
    Jadhav PK; Ala P; Woerner FJ; Chang CH; Garber SS; Anton ED; Bacheler LT
    J Med Chem; 1997 Jan; 40(2):181-91. PubMed ID: 9003516
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Effect of the active site D25N mutation on the structure, stability, and ligand binding of the mature HIV-1 protease.
    Sayer JM; Liu F; Ishima R; Weber IT; Louis JM
    J Biol Chem; 2008 May; 283(19):13459-70. PubMed ID: 18281688
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Insights into the mechanism of drug resistance: X-ray structure analysis of multi-drug resistant HIV-1 protease ritonavir complex.
    Liu Z; Yedidi RS; Wang Y; Dewdney TG; Reiter SJ; Brunzelle JS; Kovari IA; Kovari LC
    Biochem Biophys Res Commun; 2013 Feb; 431(2):232-8. PubMed ID: 23313846
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.