485 related articles for article (PubMed ID: 17219439)
1. A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth.
Shi Q; Hjelmeland AB; Keir ST; Song L; Wickman S; Jackson D; Ohmori O; Bigner DD; Friedman HS; Rich JN
Mol Carcinog; 2007 Jun; 46(6):488-96. PubMed ID: 17219439
[TBL] [Abstract][Full Text] [Related]
2. TAE226-induced apoptosis in breast cancer cells with overexpressed Src or EGFR.
Golubovskaya VM; Virnig C; Cance WG
Mol Carcinog; 2008 Mar; 47(3):222-34. PubMed ID: 17849451
[TBL] [Abstract][Full Text] [Related]
3. TAE226, a dual inhibitor for FAK and IGF-IR, has inhibitory effects on mTOR signaling in esophageal cancer cells.
Wang ZG; Fukazawa T; Nishikawa T; Watanabe N; Sakurama K; Motoki T; Takaoka M; Hatakeyama S; Omori O; Ohara T; Tanabe S; Fujiwara Y; Shirakawa Y; Yamatsuji T; Tanaka N; Naomoto Y
Oncol Rep; 2008 Dec; 20(6):1473-7. PubMed ID: 19020730
[TBL] [Abstract][Full Text] [Related]
4. Dual tyrosine kinase inhibitor for focal adhesion kinase and insulin-like growth factor-I receptor exhibits anticancer effect in esophageal adenocarcinoma in vitro and in vivo.
Watanabe N; Takaoka M; Sakurama K; Tomono Y; Hatakeyama S; Ohmori O; Motoki T; Shirakawa Y; Yamatsuji T; Haisa M; Matsuoka J; Beer DG; Nagatsuka H; Tanaka N; Naomoto Y
Clin Cancer Res; 2008 Jul; 14(14):4631-9. PubMed ID: 18628478
[TBL] [Abstract][Full Text] [Related]
5. 3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226.
Hehlgans S; Lange I; Eke I; Cordes N
Radiother Oncol; 2009 Sep; 92(3):371-8. PubMed ID: 19729215
[TBL] [Abstract][Full Text] [Related]
6. Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases.
Shi Q; Bao S; Song L; Wu Q; Bigner DD; Hjelmeland AB; Rich JN
Oncogene; 2007 Jun; 26(28):4084-94. PubMed ID: 17213807
[TBL] [Abstract][Full Text] [Related]
7. AMPA receptors promote perivascular glioma invasion via beta1 integrin-dependent adhesion to the extracellular matrix.
Piao Y; Lu L; de Groot J
Neuro Oncol; 2009 Jun; 11(3):260-73. PubMed ID: 18957620
[TBL] [Abstract][Full Text] [Related]
8. Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271.
Roberts WG; Ung E; Whalen P; Cooper B; Hulford C; Autry C; Richter D; Emerson E; Lin J; Kath J; Coleman K; Yao L; Martinez-Alsina L; Lorenzen M; Berliner M; Luzzio M; Patel N; Schmitt E; LaGreca S; Jani J; Wessel M; Marr E; Griffor M; Vajdos F
Cancer Res; 2008 Mar; 68(6):1935-44. PubMed ID: 18339875
[TBL] [Abstract][Full Text] [Related]
9. Focal adhesion kinase promotes the aggressive melanoma phenotype.
Hess AR; Postovit LM; Margaryan NV; Seftor EA; Schneider GB; Seftor RE; Nickoloff BJ; Hendrix MJ
Cancer Res; 2005 Nov; 65(21):9851-60. PubMed ID: 16267008
[TBL] [Abstract][Full Text] [Related]
10. Coadministration of sorafenib with rottlerin potently inhibits cell proliferation and migration in human malignant glioma cells.
Jane EP; Premkumar DR; Pollack IF
J Pharmacol Exp Ther; 2006 Dec; 319(3):1070-80. PubMed ID: 16959960
[TBL] [Abstract][Full Text] [Related]
11. Apigenin inhibited migration and invasion of human ovarian cancer A2780 cells through focal adhesion kinase.
Hu XW; Meng D; Fang J
Carcinogenesis; 2008 Dec; 29(12):2369-76. PubMed ID: 18974065
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo.
Liu TJ; LaFortune T; Honda T; Ohmori O; Hatakeyama S; Meyer T; Jackson D; de Groot J; Yung WK
Mol Cancer Ther; 2007 Apr; 6(4):1357-67. PubMed ID: 17431114
[TBL] [Abstract][Full Text] [Related]
13. Focal adhesion kinase: important to prostaglandin E2-mediated adhesion, migration and invasion in hepatocellular carcinoma cells.
Bai XM; Zhang W; Liu NB; Jiang H; Lou KX; Peng T; Ma J; Zhang L; Zhang H; Leng J
Oncol Rep; 2009 Jan; 21(1):129-36. PubMed ID: 19082453
[TBL] [Abstract][Full Text] [Related]
14. The effect of epidermal growth factor receptor variant III on glioma cell migration by stimulating ERK phosphorylation through the focal adhesion kinase signaling pathway.
Liu M; Yang Y; Wang C; Sun L; Mei C; Yao W; Liu Y; Shi Y; Qiu S; Fan J; Cai X; Zha X
Arch Biochem Biophys; 2010 Oct; 502(2):89-95. PubMed ID: 20650261
[TBL] [Abstract][Full Text] [Related]
15. FAK expression regulation and therapeutic potential.
Li S; Hua ZC
Adv Cancer Res; 2008; 101():45-61. PubMed ID: 19055942
[TBL] [Abstract][Full Text] [Related]
16. An altered fibronectin matrix induces anoikis of human squamous cell carcinoma cells by suppressing integrin alpha v levels and phosphorylation of FAK and ERK.
Kamarajan P; Kapila YL
Apoptosis; 2007 Dec; 12(12):2221-31. PubMed ID: 17879163
[TBL] [Abstract][Full Text] [Related]
17. Dasatinib (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells.
Johnson FM; Saigal B; Talpaz M; Donato NJ
Clin Cancer Res; 2005 Oct; 11(19 Pt 1):6924-32. PubMed ID: 16203784
[TBL] [Abstract][Full Text] [Related]
18. Migration of renal carcinoma cells is dependent on protein kinase Cdelta via beta1 integrin and focal adhesion kinase.
Brenner W; Greber I; Gudejko-Thiel J; Beitz S; Schneider E; Walenta S; Peters K; Unger R; Thüroff JW
Int J Oncol; 2008 May; 32(5):1125-31. PubMed ID: 18425341
[TBL] [Abstract][Full Text] [Related]
19. Deoxycholic acid differentially regulates focal adhesion kinase phosphorylation: role of tyrosine phosphatase ShP2.
Khare S; Holgren C; Samarel AM
Am J Physiol Gastrointest Liver Physiol; 2006 Dec; 291(6):G1100-12. PubMed ID: 16920701
[TBL] [Abstract][Full Text] [Related]
20. Regulation of focal adhesion dynamics and disassembly by phosphorylation of FAK at tyrosine 397.
Hamadi A; Bouali M; Dontenwill M; Stoeckel H; Takeda K; Rondé P
J Cell Sci; 2005 Oct; 118(Pt 19):4415-25. PubMed ID: 16159962
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
