240 related articles for article (PubMed ID: 17220171)
1. Stat5 constitutive activation rescues defects in spinal muscular atrophy.
Ting CH; Lin CW; Wen SL; Hsieh-Li HM; Li H
Hum Mol Genet; 2007 Mar; 16(5):499-514. PubMed ID: 17220171
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and biological evaluation of novel 2,4-diaminoquinazoline derivatives as SMN2 promoter activators for the potential treatment of spinal muscular atrophy.
Thurmond J; Butchbach ME; Palomo M; Pease B; Rao M; Bedell L; Keyvan M; Pai G; Mishra R; Haraldsson M; Andresson T; Bragason G; Thosteinsdottir M; Bjornsson JM; Coovert DD; Burghes AH; Gurney ME; Singh J
J Med Chem; 2008 Feb; 51(3):449-69. PubMed ID: 18205293
[TBL] [Abstract][Full Text] [Related]
3. Hydroxyurea enhances SMN2 gene expression in spinal muscular atrophy cells.
Grzeschik SM; Ganta M; Prior TW; Heavlin WD; Wang CH
Ann Neurol; 2005 Aug; 58(2):194-202. PubMed ID: 16049920
[TBL] [Abstract][Full Text] [Related]
4. A non-sequence-specific requirement for SMN protein activity: the role of aminoglycosides in inducing elevated SMN protein levels.
Wolstencroft EC; Mattis V; Bajer AA; Young PJ; Lorson CL
Hum Mol Genet; 2005 May; 14(9):1199-210. PubMed ID: 15790598
[TBL] [Abstract][Full Text] [Related]
5. Salbutamol increases SMN mRNA and protein levels in spinal muscular atrophy cells.
Angelozzi C; Borgo F; Tiziano FD; Martella A; Neri G; Brahe C
J Med Genet; 2008 Jan; 45(1):29-31. PubMed ID: 17932121
[TBL] [Abstract][Full Text] [Related]
6. Stimulating full-length SMN2 expression by delivering bifunctional RNAs via a viral vector.
Baughan T; Shababi M; Coady TH; Dickson AM; Tullis GE; Lorson CL
Mol Ther; 2006 Jul; 14(1):54-62. PubMed ID: 16580882
[TBL] [Abstract][Full Text] [Related]
7. The effect of hydroxyurea in spinal muscular atrophy cells and patients.
Liang WC; Yuo CY; Chang JG; Chen YC; Chang YF; Wang HY; Ju YH; Chiou SS; Jong YJ
J Neurol Sci; 2008 May; 268(1-2):87-94. PubMed ID: 18166199
[TBL] [Abstract][Full Text] [Related]
8. Survival motor neuron SMN1 and SMN2 gene promoters: identical sequences and differential expression in neurons and non-neuronal cells.
Boda B; Mas C; Giudicelli C; Nepote V; Guimiot F; Levacher B; Zvara A; Santha M; LeGall I; Simonneau M
Eur J Hum Genet; 2004 Sep; 12(9):729-37. PubMed ID: 15162126
[TBL] [Abstract][Full Text] [Related]
9. Diverse small-molecule modulators of SMN expression found by high-throughput compound screening: early leads towards a therapeutic for spinal muscular atrophy.
Jarecki J; Chen X; Bernardino A; Coovert DD; Whitney M; Burghes A; Stack J; Pollok BA
Hum Mol Genet; 2005 Jul; 14(14):2003-18. PubMed ID: 15944201
[TBL] [Abstract][Full Text] [Related]
10. Genetic conversion of an SMN2 gene to SMN1: a novel approach to the treatment of spinal muscular atrophy.
DiMatteo D; Callahan S; Kmiec EB
Exp Cell Res; 2008 Feb; 314(4):878-86. PubMed ID: 18078930
[TBL] [Abstract][Full Text] [Related]
11. Valproic acid increases the SMN2 protein level: a well-known drug as a potential therapy for spinal muscular atrophy.
Brichta L; Hofmann Y; Hahnen E; Siebzehnrubl FA; Raschke H; Blumcke I; Eyupoglu IY; Wirth B
Hum Mol Genet; 2003 Oct; 12(19):2481-9. PubMed ID: 12915451
[TBL] [Abstract][Full Text] [Related]
12. A sensitive assay for measuring SMN mRNA levels in peripheral blood and in muscle samples of patients affected with spinal muscular atrophy.
Vezain M; Saugier-Veber P; Melki J; Toutain A; Bieth E; Husson M; Pedespan JM; Viollet L; Pénisson-Besnier I; Fehrenbach S; Bou J; Frébourg T; Tosi M
Eur J Hum Genet; 2007 Oct; 15(10):1054-62. PubMed ID: 17609673
[TBL] [Abstract][Full Text] [Related]
13. 5-(N-ethyl-N-isopropyl)-amiloride enhances SMN2 exon 7 inclusion and protein expression in spinal muscular atrophy cells.
Yuo CY; Lin HH; Chang YS; Yang WK; Chang JG
Ann Neurol; 2008 Jan; 63(1):26-34. PubMed ID: 17924536
[TBL] [Abstract][Full Text] [Related]
14. A role for complexes of survival of motor neurons (SMN) protein with gemins and profilin in neurite-like cytoplasmic extensions of cultured nerve cells.
Sharma A; Lambrechts A; Hao le T; Le TT; Sewry CA; Ampe C; Burghes AH; Morris GE
Exp Cell Res; 2005 Sep; 309(1):185-97. PubMed ID: 15975577
[TBL] [Abstract][Full Text] [Related]
15. LBH589 induces up to 10-fold SMN protein levels by several independent mechanisms and is effective even in cells from SMA patients non-responsive to valproate.
Garbes L; Riessland M; Hölker I; Heller R; Hauke J; Tränkle C; Coras R; Blümcke I; Hahnen E; Wirth B
Hum Mol Genet; 2009 Oct; 18(19):3645-58. PubMed ID: 19584083
[TBL] [Abstract][Full Text] [Related]
16. The benzamide M344, a novel histone deacetylase inhibitor, significantly increases SMN2 RNA/protein levels in spinal muscular atrophy cells.
Riessland M; Brichta L; Hahnen E; Wirth B
Hum Genet; 2006 Aug; 120(1):101-10. PubMed ID: 16724231
[TBL] [Abstract][Full Text] [Related]
17. Spinal muscular atrophy: from gene to therapy.
Wirth B; Brichta L; Hahnen E
Semin Pediatr Neurol; 2006 Jun; 13(2):121-31. PubMed ID: 17027862
[TBL] [Abstract][Full Text] [Related]
18. Spinal muscular atrophy: state-of-the-art and therapeutic perspectives.
Wirth B
Amyotroph Lateral Scler Other Motor Neuron Disord; 2002 Jun; 3(2):87-95. PubMed ID: 12215230
[TBL] [Abstract][Full Text] [Related]
19. Aclarubicin treatment restores SMN levels to cells derived from type I spinal muscular atrophy patients.
Andreassi C; Jarecki J; Zhou J; Coovert DD; Monani UR; Chen X; Whitney M; Pollok B; Zhang M; Androphy E; Burghes AH
Hum Mol Genet; 2001 Nov; 10(24):2841-9. PubMed ID: 11734549
[TBL] [Abstract][Full Text] [Related]
20. Extracellular pH change modulates the exon 7 splicing in SMN2 mRNA.
Chen YC; Yuo CY; Yang WK; Jong YJ; Lin HH; Chang YS; Chang JG
Mol Cell Neurosci; 2008 Oct; 39(2):268-72. PubMed ID: 18672065
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]