BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 17223255)

  • 1. Identification of the molecular switch that regulates access of 5alpha-DHT to the androgen receptor.
    Penning TM; Bauman DR; Jin Y; Rizner TL
    Mol Cell Endocrinol; 2007 Feb; 265-266():77-82. PubMed ID: 17223255
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human type 3 3alpha-hydroxysteroid dehydrogenase (aldo-keto reductase 1C2) and androgen metabolism in prostate cells.
    Rizner TL; Lin HK; Peehl DM; Steckelbroeck S; Bauman DR; Penning TM
    Endocrinology; 2003 Jul; 144(7):2922-32. PubMed ID: 12810547
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of human type 3 3alpha-hydroxysteroid dehydrogenase (AKR1C2) in androgen metabolism of prostate cancer cells.
    Rizner TL; Lin HK; Penning TM
    Chem Biol Interact; 2003 Feb; 143-144():401-9. PubMed ID: 12604227
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pre-receptor regulation of the androgen receptor.
    Penning TM; Jin Y; Rizner TL; Bauman DR
    Mol Cell Endocrinol; 2008 Jan; 281(1-2):1-8. PubMed ID: 18060684
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of the major oxidative 3alpha-hydroxysteroid dehydrogenase in human prostate that converts 5alpha-androstane-3alpha,17beta-diol to 5alpha-dihydrotestosterone: a potential therapeutic target for androgen-dependent disease.
    Bauman DR; Steckelbroeck S; Williams MV; Peehl DM; Penning TM
    Mol Endocrinol; 2006 Feb; 20(2):444-58. PubMed ID: 16179381
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Androgen inactivation and steroid-converting enzyme expression in abdominal adipose tissue in men.
    Blouin K; Richard C; Brochu G; Hould FS; Lebel S; Marceau S; Biron S; Luu-The V; Tchernof A
    J Endocrinol; 2006 Dec; 191(3):637-49. PubMed ID: 17170221
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Steroid 5alpha-reductases and 3alpha-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism.
    Jin Y; Penning TM
    Best Pract Res Clin Endocrinol Metab; 2001 Mar; 15(1):79-94. PubMed ID: 11469812
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transcript profiling of the androgen signal in normal prostate, benign prostatic hyperplasia, and prostate cancer.
    Bauman DR; Steckelbroeck S; Peehl DM; Penning TM
    Endocrinology; 2006 Dec; 147(12):5806-16. PubMed ID: 16959841
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expression and characterization of recombinant type 2 3 alpha-hydroxysteroid dehydrogenase (HSD) from human prostate: demonstration of bifunctional 3 alpha/17 beta-HSD activity and cellular distribution.
    Lin HK; Jez JM; Schlegel BP; Peehl DM; Pachter JA; Penning TM
    Mol Endocrinol; 1997 Dec; 11(13):1971-84. PubMed ID: 9415401
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multiple steps determine the overall rate of the reduction of 5alpha-dihydrotestosterone catalyzed by human type 3 3alpha-hydroxysteroid dehydrogenase: implications for the elimination of androgens.
    Jin Y; Penning TM
    Biochemistry; 2006 Oct; 45(43):13054-63. PubMed ID: 17059222
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone metabolism and action.
    Steckelbroeck S; Jin Y; Gopishetty S; Oyesanmi B; Penning TM
    J Biol Chem; 2004 Mar; 279(11):10784-95. PubMed ID: 14672942
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Partitioning of 5alpha-dihydrotestosterone and 5alpha-androstane-3alpha, 17beta-diol activated pathways for stimulating human prostate cancer LNCaP cell proliferation.
    Nunlist EH; Dozmorov I; Tang Y; Cowan R; Centola M; Lin HK
    J Steroid Biochem Mol Biol; 2004 Jul; 91(3):157-70. PubMed ID: 15276623
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 5alpha-androstane-3alpha,17beta-diol supports human prostate cancer cell survival and proliferation through androgen receptor-independent signaling pathways: implication of androgen-independent prostate cancer progression.
    Yang Q; Titus MA; Fung KM; Lin HK
    J Cell Biochem; 2008 Aug; 104(5):1612-24. PubMed ID: 18320593
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer.
    Mohler JL; Titus MA; Bai S; Kennerley BJ; Lih FB; Tomer KB; Wilson EM
    Cancer Res; 2011 Feb; 71(4):1486-96. PubMed ID: 21303972
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Conversion of mammalian 3alpha-hydroxysteroid dehydrogenase to 20alpha-hydroxysteroid dehydrogenase using loop chimeras: changing specificity from androgens to progestins.
    Ma H; Penning TM
    Proc Natl Acad Sci U S A; 1999 Sep; 96(20):11161-6. PubMed ID: 10500147
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Function of human brain short chain L-3-hydroxyacyl coenzyme A dehydrogenase in androgen metabolism.
    He XY; Merz G; Yang YZ; Pullakart R; Mehta P; Schulz H; Yang SY
    Biochim Biophys Acta; 2000 Apr; 1484(2-3):267-77. PubMed ID: 10760475
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-function relationships in 3alpha-hydroxysteroid dehydrogenases: a comparison of the rat and human isoforms.
    Penning TM; Jin Y; Heredia VV; Lewis M
    J Steroid Biochem Mol Biol; 2003 Jun; 85(2-5):247-55. PubMed ID: 12943710
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hydroxysteroid dehydrogenases and pre-receptor regulation of steroid hormone action.
    Penning TM
    Hum Reprod Update; 2003; 9(3):193-205. PubMed ID: 12861966
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular determinants of steroid recognition and catalysis in aldo-keto reductases. Lessons from 3alpha-hydroxysteroid dehydrogenase.
    Penning TM
    J Steroid Biochem Mol Biol; 1999; 69(1-6):211-25. PubMed ID: 10418995
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Androgen formation and metabolism in the pulmonary epithelial cell line A549: expression of 17beta-hydroxysteroid dehydrogenase type 5 and 3alpha-hydroxysteroid dehydrogenase type 3.
    Provost PR; Blomquist CH; Godin C; Huang XF; Flamand N; Luu-The V; Nadeau D; Tremblay Y
    Endocrinology; 2000 Aug; 141(8):2786-94. PubMed ID: 10919264
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.