126 related articles for article (PubMed ID: 17225251)
1. Identification of intracellular targets of small molecular weight chemical compounds using affinity chromatography.
Guiffant D; Tribouillard D; Gug F; Galons H; Meijer L; Blondel M; Bach S
Biotechnol J; 2007 Jan; 2(1):68-75. PubMed ID: 17225251
[TBL] [Abstract][Full Text] [Related]
2. [Development of antituberculous drugs: current status and future prospects].
Tomioka H; Namba K
Kekkaku; 2006 Dec; 81(12):753-74. PubMed ID: 17240921
[TBL] [Abstract][Full Text] [Related]
3. Kinase selectivity profiling by inhibitor affinity chromatography.
Valsasina B; Kalisz HM; Isacchi A
Expert Rev Proteomics; 2004 Oct; 1(3):303-15. PubMed ID: 15966827
[TBL] [Abstract][Full Text] [Related]
4. Use of ligand based models for protein domains to predict novel molecular targets and applications to triage affinity chromatography data.
Bender A; Mikhailov D; Glick M; Scheiber J; Davies JW; Cleaver S; Marshall S; Tallarico JA; Harrington E; Cornella-Taracido I; Jenkins JL
J Proteome Res; 2009 May; 8(5):2575-85. PubMed ID: 19271732
[TBL] [Abstract][Full Text] [Related]
5. Finding the target after screening the phenotype.
Hart CP
Drug Discov Today; 2005 Apr; 10(7):513-9. PubMed ID: 15809197
[TBL] [Abstract][Full Text] [Related]
6. [Strategy of molecular design of drugs: the unification of macro-properties and micro-structures of a molecule].
Guo ZR
Yao Xue Xue Bao; 2008 Mar; 43(3):227-33. PubMed ID: 18630256
[TBL] [Abstract][Full Text] [Related]
7. Tools and methodologies capable of isolating and identifying a target molecule for a bioactive compound.
Sakamoto S; Hatakeyama M; Ito T; Handa H
Bioorg Med Chem; 2012 Mar; 20(6):1990-2001. PubMed ID: 22264760
[TBL] [Abstract][Full Text] [Related]
8. Pharmacological promiscuity: dependence on compound properties and target specificity in a set of recent Roche compounds.
Peters JU; Schnider P; Mattei P; Kansy M
ChemMedChem; 2009 Apr; 4(4):680-6. PubMed ID: 19266525
[TBL] [Abstract][Full Text] [Related]
9. Methods for computer-aided chemical biology. Part 2: Evaluation of compound selectivity using 2D molecular fingerprints.
Vogt I; Stumpfe D; Ahmed HE; Bajorath J
Chem Biol Drug Des; 2007 Sep; 70(3):195-205. PubMed ID: 17718714
[TBL] [Abstract][Full Text] [Related]
10. Drug target deconvolution by chemical proteomics.
Raida M
Curr Opin Chem Biol; 2011 Aug; 15(4):570-5. PubMed ID: 21763176
[TBL] [Abstract][Full Text] [Related]
11. [Strategy of molecular drug design: hits, leads and drug candidates].
Guo ZR
Yao Xue Xue Bao; 2008 Sep; 43(9):898-904. PubMed ID: 19048779
[TBL] [Abstract][Full Text] [Related]
12. Revealing promiscuous drug-target interactions by chemical proteomics.
Bantscheff M; Scholten A; Heck AJ
Drug Discov Today; 2009 Nov; 14(21-22):1021-9. PubMed ID: 19596079
[TBL] [Abstract][Full Text] [Related]
13. Fragment-based drug design: how big is too big?
Hajduk PJ
J Med Chem; 2006 Nov; 49(24):6972-6. PubMed ID: 17125250
[TBL] [Abstract][Full Text] [Related]
14. Identification of the cellular targets of bioactive small organic molecules using affinity reagents.
Leslie BJ; Hergenrother PJ
Chem Soc Rev; 2008 Jul; 37(7):1347-60. PubMed ID: 18568161
[TBL] [Abstract][Full Text] [Related]
15. Chemical proteomics for drug discovery based on compound-immobilized affinity chromatography.
Katayama H; Oda Y
J Chromatogr B Analyt Technol Biomed Life Sci; 2007 Aug; 855(1):21-7. PubMed ID: 17241823
[TBL] [Abstract][Full Text] [Related]
16. Drugs in other drugs: a new look at drugs as fragments.
Siegel MG; Vieth M
Drug Discov Today; 2007 Jan; 12(1-2):71-9. PubMed ID: 17198975
[TBL] [Abstract][Full Text] [Related]
17. Defining optimum lipophilicity and molecular weight ranges for drug candidates-Molecular weight dependent lower logD limits based on permeability.
Waring MJ
Bioorg Med Chem Lett; 2009 May; 19(10):2844-51. PubMed ID: 19361989
[TBL] [Abstract][Full Text] [Related]
18. Importance of molecular computer modeling in anticancer drug development.
Geromichalos GD
J BUON; 2007 Sep; 12 Suppl 1():S101-18. PubMed ID: 17935268
[TBL] [Abstract][Full Text] [Related]
19. Analysis of pharmacology data and the prediction of adverse drug reactions and off-target effects from chemical structure.
Bender A; Scheiber J; Glick M; Davies JW; Azzaoui K; Hamon J; Urban L; Whitebread S; Jenkins JL
ChemMedChem; 2007 Jun; 2(6):861-73. PubMed ID: 17477341
[TBL] [Abstract][Full Text] [Related]
20. An immuno-chemo-proteomics method for drug target deconvolution.
Saxena C; Zhen E; Higgs RE; Hale JE
J Proteome Res; 2008 Aug; 7(8):3490-7. PubMed ID: 18590316
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]