179 related articles for article (PubMed ID: 17239587)
21. Discovery of novel benzimidazoles as potent inhibitors of TIE-2 and VEGFR-2 tyrosine kinase receptors.
Hasegawa M; Nishigaki N; Washio Y; Kano K; Harris PA; Sato H; Mori I; West RI; Shibahara M; Toyoda H; Wang L; Nolte RT; Veal JM; Cheung M
J Med Chem; 2007 Sep; 50(18):4453-70. PubMed ID: 17676829
[TBL] [Abstract][Full Text] [Related]
22. 4-Acylamino-6-arylfuro[2,3-d]pyrimidines: potent and selective glycogen synthase kinase-3 inhibitors.
Maeda Y; Nakano M; Sato H; Miyazaki Y; Schweiker SL; Smith JL; Truesdale AT
Bioorg Med Chem Lett; 2004 Aug; 14(15):3907-11. PubMed ID: 15225695
[TBL] [Abstract][Full Text] [Related]
23. Thienopyridine urea inhibitors of KDR kinase.
Heyman HR; Frey RR; Bousquet PF; Cunha GA; Moskey MD; Ahmed AA; Soni NB; Marcotte PA; Pease LJ; Glaser KB; Yates M; Bouska JJ; Albert DH; Black-Schaefer CL; Dandliker PJ; Stewart KD; Rafferty P; Davidsen SK; Michaelides MR; Curtin ML
Bioorg Med Chem Lett; 2007 Mar; 17(5):1246-9. PubMed ID: 17188869
[TBL] [Abstract][Full Text] [Related]
24. Discovery of indenopyrazoles as EGFR and VEGFR-2 tyrosine kinase inhibitors by in silico high-throughput screening.
Usui T; Ban HS; Kawada J; Hirokawa T; Nakamura H
Bioorg Med Chem Lett; 2008 Jan; 18(1):285-8. PubMed ID: 17983745
[TBL] [Abstract][Full Text] [Related]
25. Discovery of novel 1,2,3,4-tetrahydroisoquinolines and 3,4-dihydroisoquinoline-1(2H)-ones as potent and selective inhibitors of KDR: synthesis, SAR, and pharmacokinetic properties.
Choquette D; Teffera Y; Polverino A; Harmange JC
Bioorg Med Chem Lett; 2008 Jul; 18(14):4054-8. PubMed ID: 18573658
[TBL] [Abstract][Full Text] [Related]
26. Pyrazolone based TGFbetaR1 kinase inhibitors.
Guckian K; Carter MB; Lin EY; Choi M; Sun L; Boriack-Sjodin PA; Chuaqui C; Lane B; Cheung K; Ling L; Lee WC
Bioorg Med Chem Lett; 2010 Jan; 20(1):326-9. PubMed ID: 19914068
[TBL] [Abstract][Full Text] [Related]
27. Pharmacophore modeling and virtual screening studies for new VEGFR-2 kinase inhibitors.
Lee K; Jeong KW; Lee Y; Song JY; Kim MS; Lee GS; Kim Y
Eur J Med Chem; 2010 Nov; 45(11):5420-7. PubMed ID: 20869793
[TBL] [Abstract][Full Text] [Related]
28. Identification of aminopyrazolopyridine ureas as potent VEGFR/PDGFR multitargeted kinase inhibitors.
Dai Y; Hartandi K; Soni NB; Pease LJ; Reuter DR; Olson AM; Osterling DJ; Doktor SZ; Albert DH; Bouska JJ; Glaser KB; Marcotte PA; Stewart KD; Davidsen SK; Michaelides MR
Bioorg Med Chem Lett; 2008 Jan; 18(1):386-90. PubMed ID: 18023347
[TBL] [Abstract][Full Text] [Related]
29. Synthesis, biological evaluation, and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis: part 2. Synthesis of rigid pyrazolones.
Castagnolo D; Manetti F; Radi M; Bechi B; Pagano M; De Logu A; Meleddu R; Saddi M; Botta M
Bioorg Med Chem; 2009 Aug; 17(15):5716-21. PubMed ID: 19581099
[TBL] [Abstract][Full Text] [Related]
30. Synthesis and biological activity of N,N-dialkylaminoalkyl-substituted bisindolyl and diphenyl pyrazolone derivatives.
Braña MF; Gradillas A; Ovalles AG; López B; Acero N; Llinares F; Muñoz Mingarro D
Bioorg Med Chem; 2006 Jan; 14(1):9-16. PubMed ID: 16263294
[TBL] [Abstract][Full Text] [Related]
31. Scaffold oriented synthesis. Part 1: Design, preparation, and biological evaluation of thienopyrazoles as kinase inhibitors.
Akritopoulou-Zanze I; Darczak D; Sarris K; Phelan KM; Huth JR; Song D; Johnson EF; Jia Y; Djuric SW
Bioorg Med Chem Lett; 2006 Jan; 16(1):96-9. PubMed ID: 16216502
[TBL] [Abstract][Full Text] [Related]
32. Hit-to-lead optimization of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of KDR kinase inhibitors.
Dinges J; Akritopoulou-Zanze I; Arnold LD; Barlozzari T; Bousquet PF; Cunha GA; Ericsson AM; Iwasaki N; Michaelides MR; Ogawa N; Phelan KM; Rafferty P; Sowin TJ; Stewart KD; Tokuyama R; Xia Z; Zhang HQ
Bioorg Med Chem Lett; 2006 Aug; 16(16):4371-5. PubMed ID: 16750628
[TBL] [Abstract][Full Text] [Related]
33. Efficient syntheses of KDR kinase inhibitors using a Pd-catalyzed tandem C-N/Suzuki coupling as the key step.
Fang YQ; Karisch R; Lautens M
J Org Chem; 2007 Feb; 72(4):1341-6. PubMed ID: 17253753
[TBL] [Abstract][Full Text] [Related]
34. Synthesis, structural analysis, and SAR studies of triazine derivatives as potent, selective Tie-2 inhibitors.
Hodous BL; Geuns-Meyer SD; Hughes PE; Albrecht BK; Bellon S; Caenepeel S; Cee VJ; Chaffee SC; Emery M; Fretland J; Gallant P; Gu Y; Johnson RE; Kim JL; Long AM; Morrison M; Olivieri PR; Patel VF; Polverino A; Rose P; Wang L; Zhao H
Bioorg Med Chem Lett; 2007 May; 17(10):2886-9. PubMed ID: 17350837
[TBL] [Abstract][Full Text] [Related]
35. Inhibitors of VEGF receptors-1 and -2 based on the 2-((pyridin-4-yl)ethyl)pyridine template.
Kiselyov AS; Semenova M; Semenov VV; Milligan D
Bioorg Med Chem Lett; 2006 Apr; 16(7):1913-9. PubMed ID: 16460936
[TBL] [Abstract][Full Text] [Related]
36. Discovery of N-phenyl nicotinamides as potent inhibitors of Kdr.
Dominguez C; Smith L; Huang Q; Yuan C; Ouyang X; Cai L; Chen P; Kim J; Harvey T; Syed R; Kim TS; Tasker A; Wang L; Zhang M; Coxon A; Bready J; Starnes C; Chen D; Gan Y; Neervannan S; Kumar G; Polverino A; Kendall R
Bioorg Med Chem Lett; 2007 Nov; 17(21):6003-8. PubMed ID: 17869515
[TBL] [Abstract][Full Text] [Related]
37. Evolution of a highly selective and potent 2-(pyridin-2-yl)-1,3,5-triazine Tie-2 kinase inhibitor.
Hodous BL; Geuns-Meyer SD; Hughes PE; Albrecht BK; Bellon S; Bready J; Caenepeel S; Cee VJ; Chaffee SC; Coxon A; Emery M; Fretland J; Gallant P; Gu Y; Hoffman D; Johnson RE; Kendall R; Kim JL; Long AM; Morrison M; Olivieri PR; Patel VF; Polverino A; Rose P; Tempest P; Wang L; Whittington DA; Zhao H
J Med Chem; 2007 Feb; 50(4):611-26. PubMed ID: 17253678
[TBL] [Abstract][Full Text] [Related]
38. 2-((1H-Azol-1-yl)methyl)-N-arylbenzamides: novel dual inhibitors of VEGFR-1/2 kinases.
Kiselyov AS; Semenova M; Semenov VV; Piatnitski E
Bioorg Med Chem Lett; 2006 Mar; 16(6):1726-30. PubMed ID: 16364640
[TBL] [Abstract][Full Text] [Related]
39. Isothiazolopyrimidines and isoxazolopyrimidines as novel multi-targeted inhibitors of receptor tyrosine kinases.
Ji Z; Ahmed AA; Albert DH; Bouska JJ; Bousquet PF; Cunha GA; Glaser KB; Guo J; Li J; Marcotte PA; Moskey MD; Pease LJ; Stewart KD; Yates M; Davidsen SK; Michaelides MR
Bioorg Med Chem Lett; 2006 Aug; 16(16):4326-30. PubMed ID: 16735117
[TBL] [Abstract][Full Text] [Related]
40. In-silico fragment-based identification of novel angiogenesis inhibitors.
Dakshanamurthy S; Kim M; Brown ML; Byers SW
Bioorg Med Chem Lett; 2007 Aug; 17(16):4551-6. PubMed ID: 17591441
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
