BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

281 related articles for article (PubMed ID: 17240975)

  • 1. Biosynthetic characterization and chemoenzymatic assembly of the cryptophycins. Potent anticancer agents from cyanobionts.
    Magarvey NA; Beck ZQ; Golakoti T; Ding Y; Huber U; Hemscheidt TK; Abelson D; Moore RE; Sherman DH
    ACS Chem Biol; 2006 Dec; 1(12):766-79. PubMed ID: 17240975
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chemoenzymatic synthesis of cryptophycin/arenastatin natural products.
    Beck ZQ; Aldrich CC; Magarvey NA; Georg GI; Sherman DH
    Biochemistry; 2005 Oct; 44(41):13457-66. PubMed ID: 16216069
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The tallysomycin biosynthetic gene cluster from Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insights into the biosynthesis of the bleomycin family of antitumor antibiotics.
    Tao M; Wang L; Wendt-Pienkowski E; George NP; Galm U; Zhang G; Coughlin JM; Shen B
    Mol Biosyst; 2007 Jan; 3(1):60-74. PubMed ID: 17216057
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of a gene cluster responsible for the biosynthesis of anticancer agent FK228 in Chromobacterium violaceum No. 968.
    Cheng YQ; Yang M; Matter AM
    Appl Environ Microbiol; 2007 Jun; 73(11):3460-9. PubMed ID: 17400765
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cryptophycin anticancer drugs revisited.
    Rohr J
    ACS Chem Biol; 2006 Dec; 1(12):747-50. PubMed ID: 17240971
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Analysis of the cryptophycin P450 epoxidase reveals substrate tolerance and cooperativity.
    Ding Y; Seufert WH; Beck ZQ; Sherman DH
    J Am Chem Soc; 2008 Apr; 130(16):5492-8. PubMed ID: 18366166
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sequencing and modular analysis of the hybrid non-ribosomal peptide synthase - polyketide synthase gene cluster from the marine sponge Hymeniacidon perleve-associated bacterium Pseudoalteromonas sp. strain NJ631.
    Zhu P; Zheng Y; You Y; Yan X; Shao J
    Can J Microbiol; 2009 Mar; 55(3):219-27. PubMed ID: 19370064
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Three new cryptophycins from Nostoc sp. GSV 224.
    Subbaraju GV; Golakoti T; Patterson GM; Moore RE
    J Nat Prod; 1997 Mar; 60(3):302-5. PubMed ID: 9090872
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of the locus of genes encoding enzymes producing heptadepsipeptide micropeptin in the unicellular cyanobacterium Microcystis.
    Nishizawa T; Ueda A; Nakano T; Nishizawa A; Miura T; Asayama M; Fujii K; Harada K; Shirai M
    J Biochem; 2011 Apr; 149(4):475-85. PubMed ID: 21212071
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nonribosomal biosynthesis of fusaricidins by Paenibacillus polymyxa PKB1 involves direct activation of a D-amino acid.
    Li J; Jensen SE
    Chem Biol; 2008 Feb; 15(2):118-27. PubMed ID: 18291316
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.
    Xu Z; Jakobi K; Welzel K; Hertweck C
    Chem Biol; 2005 May; 12(5):579-88. PubMed ID: 15911378
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Isolation and structure determination of cryptophycins 38, 326, and 327 from the terrestrial cyanobacterium Nostoc sp. GSV 224.
    Chaganty S; Golakoti T; Heltzel C; Moore RE; Yoshida WY
    J Nat Prod; 2004 Aug; 67(8):1403-6. PubMed ID: 15332864
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nostophycin biosynthesis is directed by a hybrid polyketide synthase-nonribosomal peptide synthetase in the toxic cyanobacterium Nostoc sp. strain 152.
    Fewer DP; Osterholm J; Rouhiainen L; Jokela J; Wahlsten M; Sivonen K
    Appl Environ Microbiol; 2011 Nov; 77(22):8034-40. PubMed ID: 21948844
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Myxovirescin A biosynthesis is directed by hybrid polyketide synthases/nonribosomal peptide synthetase, 3-hydroxy-3-methylglutaryl-CoA synthases, and trans-acting acyltransferases.
    Simunovic V; Zapp J; Rachid S; Krug D; Meiser P; Müller R
    Chembiochem; 2006 Aug; 7(8):1206-20. PubMed ID: 16835859
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure and biosynthesis of myxochromides S1-3 in Stigmatella aurantiaca: evidence for an iterative bacterial type I polyketide synthase and for module skipping in nonribosomal peptide biosynthesis.
    Wenzel SC; Kunze B; Höfle G; Silakowski B; Scharfe M; Blöcker H; Müller R
    Chembiochem; 2005 Feb; 6(2):375-85. PubMed ID: 15651040
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The biosynthetic genes for disorazoles, potent cytotoxic compounds that disrupt microtubule formation.
    Carvalho R; Reid R; Viswanathan N; Gramajo H; Julien B
    Gene; 2005 Oct; 359():91-8. PubMed ID: 16084035
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Efficient and versatile stereoselective synthesis of cryptophycins.
    Mast CA; Eissler S; Stoncius A; Stammler HG; Neumann B; Sewald N
    Chemistry; 2005 Aug; 11(16):4667-77. PubMed ID: 15915529
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chemoenzymatic synthesis of cryptophycin anticancer agents by an ester bond-forming non-ribosomal peptide synthetase module.
    Ding Y; Rath CM; Bolduc KL; Håkansson K; Sherman DH
    J Am Chem Soc; 2011 Sep; 133(37):14492-5. PubMed ID: 21823639
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rational biosynthetic engineering for optimization of geldanamycin analogues.
    Kim W; Lee D; Hong SS; Na Z; Shin JC; Roh SH; Wu CZ; Choi O; Lee K; Shen YM; Paik SG; Lee JJ; Hong YS
    Chembiochem; 2009 May; 10(7):1243-51. PubMed ID: 19308924
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from Streptomyces griseus.
    Wendt-Pienkowski E; Huang Y; Zhang J; Li B; Jiang H; Kwon H; Hutchinson CR; Shen B
    J Am Chem Soc; 2005 Nov; 127(47):16442-52. PubMed ID: 16305230
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.