435 related articles for article (PubMed ID: 17241619)
1. The human hepatoma HepaRG cells: a highly differentiated model for studies of liver metabolism and toxicity of xenobiotics.
Guillouzo A; Corlu A; Aninat C; Glaise D; Morel F; Guguen-Guillouzo C
Chem Biol Interact; 2007 May; 168(1):66-73. PubMed ID: 17241619
[TBL] [Abstract][Full Text] [Related]
2. Regulation of Drug Metabolism by the Interplay of Inflammatory Signaling, Steatosis, and Xeno-Sensing Receptors in HepaRG Cells.
Tanner N; Kubik L; Luckert C; Thomas M; Hofmann U; Zanger UM; Böhmert L; Lampen A; Braeuning A
Drug Metab Dispos; 2018 Apr; 46(4):326-335. PubMed ID: 29330220
[TBL] [Abstract][Full Text] [Related]
3. Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists.
Braeuning A; Thomas M; Hofmann U; Vetter S; Zeller E; Petzuch B; Johänning J; Schroth W; Weiss TS; Zanger UM; Schwarz M
Drug Metab Dispos; 2015 Nov; 43(11):1781-7. PubMed ID: 26310804
[TBL] [Abstract][Full Text] [Related]
4. Human Hepatic HepaRG Cells Maintain an Organotypic Phenotype with High Intrinsic CYP450 Activity/Metabolism and Significantly Outperform Standard HepG2/C3A Cells for Pharmaceutical and Therapeutic Applications.
Nelson LJ; Morgan K; Treskes P; Samuel K; Henderson CJ; LeBled C; Homer N; Grant MH; Hayes PC; Plevris JN
Basic Clin Pharmacol Toxicol; 2017 Jan; 120(1):30-37. PubMed ID: 27285124
[TBL] [Abstract][Full Text] [Related]
5. Creation and Preliminary Characterization of Pregnane X Receptor and Constitutive Androstane Receptor Knockout Rats.
Forbes KP; Kouranova E; Tinker D; Janowski K; Cortner D; McCoy A; Cui X
Drug Metab Dispos; 2017 Oct; 45(10):1068-1076. PubMed ID: 28716828
[TBL] [Abstract][Full Text] [Related]
6. Stable Overexpression of the Constitutive Androstane Receptor Reduces the Requirement for Culture with Dimethyl Sulfoxide for High Drug Metabolism in HepaRG Cells.
van der Mark VA; Rudi de Waart D; Shevchenko V; Elferink RP; Chamuleau RA; Hoekstra R
Drug Metab Dispos; 2017 Jan; 45(1):56-67. PubMed ID: 27780834
[TBL] [Abstract][Full Text] [Related]
7. Critical differences in drug metabolic properties of human hepatic cellular models, including primary human hepatocytes, stem cell derived hepatocytes, and hepatoma cell lines.
Kvist AJ; Kanebratt KP; Walentinsson A; Palmgren H; O'Hara M; Björkbom A; Andersson LC; Ahlqvist M; Andersson TB
Biochem Pharmacol; 2018 Sep; 155():124-140. PubMed ID: 29953844
[TBL] [Abstract][Full Text] [Related]
8. Epigenetic Modifications of the Liver Tumor Cell Line HepG2 Increase Their Drug Metabolic Capacity.
Ruoß M; Damm G; Vosough M; Ehret L; Grom-Baumgarten C; Petkov M; Naddalin S; Ladurner R; Seehofer D; Nussler A; Sajadian S
Int J Mol Sci; 2019 Jan; 20(2):. PubMed ID: 30654452
[TBL] [Abstract][Full Text] [Related]
9. NADPH-cytochrome P450 reductase expression and enzymatic activity in primary-like human hepatocytes and HepG2 cells for in vitro biotransformation studies.
Schulz C; Kammerer S; Küpper JH
Clin Hemorheol Microcirc; 2019; 73(1):249-260. PubMed ID: 31561354
[TBL] [Abstract][Full Text] [Related]
10. Cross-species analysis of hepatic cytochrome P450 and transport protein expression.
Hammer H; Schmidt F; Marx-Stoelting P; Pötz O; Braeuning A
Arch Toxicol; 2021 Jan; 95(1):117-133. PubMed ID: 33150952
[TBL] [Abstract][Full Text] [Related]
11. Comparative analysis of 3D culture methods on human HepG2 cells.
Luckert C; Schulz C; Lehmann N; Thomas M; Hofmann U; Hammad S; Hengstler JG; Braeuning A; Lampen A; Hessel S
Arch Toxicol; 2017 Jan; 91(1):393-406. PubMed ID: 26872951
[TBL] [Abstract][Full Text] [Related]
12. Comparison of Drug Metabolism and Its Related Hepatotoxic Effects in HepaRG, Cryopreserved Human Hepatocytes, and HepG2 Cell Cultures.
Yokoyama Y; Sasaki Y; Terasaki N; Kawataki T; Takekawa K; Iwase Y; Shimizu T; Sanoh S; Ohta S
Biol Pharm Bull; 2018 May; 41(5):722-732. PubMed ID: 29445054
[TBL] [Abstract][Full Text] [Related]
13. Functional polarization of human hepatoma HepaRG cells in response to forskolin.
Mayati A; Moreau A; Le Vée M; Bruyère A; Jouan E; Denizot C; Parmentier Y; Fardel O
Sci Rep; 2018 Oct; 8(1):16115. PubMed ID: 30382126
[TBL] [Abstract][Full Text] [Related]
14. Role of Nuclear Receptors PXR and CAR in Xenobiotic-Induced Hepatocyte Proliferation and Chemical Carcinogenesis.
Yoshinari K
Biol Pharm Bull; 2019; 42(8):1243-1252. PubMed ID: 31366862
[TBL] [Abstract][Full Text] [Related]
15. Cytochrome P450-dependent drug oxidation activities in commercially available hepatocytes derived from human induced pluripotent stem cells cultured for 3 weeks.
Murayama N; Yamazaki H
J Toxicol Sci; 2018; 43(4):241-245. PubMed ID: 29618712
[TBL] [Abstract][Full Text] [Related]
16. Overexpression of the constitutive androstane receptor and shaken 3D-culturing increase biotransformation and oxidative phosphorylation and sensitivity to mitochondrial amiodarone toxicity of HepaRG cells.
van der Mark VA; Adam AAA; Chang JC; Oude Elferink RP; Chamuleau RAFM; Hoekstra R
Toxicol Appl Pharmacol; 2020 Jul; 399():115055. PubMed ID: 32428594
[TBL] [Abstract][Full Text] [Related]
17. Hepatocellular carcinoma: Gene expression profiling and regulation of xenobiotic-metabolizing cytochromes P450.
Nekvindova J; Mrkvicova A; Zubanova V; Hyrslova Vaculova A; Anzenbacher P; Soucek P; Radova L; Slaby O; Kiss I; Vondracek J; Spicakova A; Bohovicova L; Fabian P; Kala Z; Palicka V
Biochem Pharmacol; 2020 Jul; 177():113912. PubMed ID: 32173367
[TBL] [Abstract][Full Text] [Related]
18. Cytochrome P450 1A1/2, 2B6 and 3A4 HepaRG Cell-Based Biosensors to Monitor Hepatocyte Differentiation, Drug Metabolism and Toxicity.
Vlach M; Quesnot N; Dubois-Pot-Schneider H; Ribault C; Verres Y; Petitjean K; Rauch C; Morel F; Robin MA; Corlu A; Loyer P
Sensors (Basel); 2019 May; 19(10):. PubMed ID: 31096615
[TBL] [Abstract][Full Text] [Related]
19. Comparison of HepaRG cells following growth in proliferative and differentiated culture conditions reveals distinct bioenergetic profiles.
Young CKJ; Young MJ
Cell Cycle; 2019 Feb; 18(4):476-499. PubMed ID: 30755072
[TBL] [Abstract][Full Text] [Related]
20. Comparative Analysis of Long Noncoding RNA Expression in Human Hepatocyte Cell Lines and Liver.
Burenina OY; Zatsepin TS; Kim EF; Metelin AV; Skvortsov DA; Rubtsova MP; Dontsova OA
Dokl Biochem Biophys; 2020 Jul; 493(1):181-184. PubMed ID: 32894460
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
