136 related articles for article (PubMed ID: 17251017)
1. Carbonic anhydrase inhibitors: binding of an antiglaucoma glycosyl-sulfanilamide derivative to human isoform II and its consequences for the drug design of enzyme inhibitors incorporating sugar moieties.
Di Fiore A; Scozzafava A; Winum JY; Montero JL; Pedone C; Supuran CT; De Simone G
Bioorg Med Chem Lett; 2007 Mar; 17(6):1726-31. PubMed ID: 17251017
[TBL] [Abstract][Full Text] [Related]
2. Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxib.
Di Fiore A; Pedone C; D'Ambrosio K; Scozzafava A; De Simone G; Supuran CT
Bioorg Med Chem Lett; 2006 Jan; 16(2):437-42. PubMed ID: 16290146
[TBL] [Abstract][Full Text] [Related]
3. Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II.
Di Fiore A; De Simone G; Menchise V; Pedone C; Casini A; Scozzafava A; Supuran CT
Bioorg Med Chem Lett; 2005 Apr; 15(7):1937-42. PubMed ID: 15780637
[TBL] [Abstract][Full Text] [Related]
4. Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a topically acting antiglaucoma sulfonamide.
Abbate F; Casini A; Scozzafava A; Supuran CT
Bioorg Med Chem Lett; 2004 May; 14(9):2357-61. PubMed ID: 15081040
[TBL] [Abstract][Full Text] [Related]
5. Carbonic anhydrase inhibitors: clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozyme II, exemplified by the crystal structure of the topiramate sulfamide analogue.
Winum JY; Temperini C; El Cheikh K; Innocenti A; Vullo D; Ciattini S; Montero JL; Scozzafava A; Supuran CT
J Med Chem; 2006 Nov; 49(24):7024-31. PubMed ID: 17125255
[TBL] [Abstract][Full Text] [Related]
6. Carbonic anhydrase inhibitors. X-ray crystal studies of the carbonic anhydrase II-trithiocarbonate adduct--an inhibitor mimicking the sulfonamide and urea binding to the enzyme.
Temperini C; Scozzafava A; Supuran CT
Bioorg Med Chem Lett; 2010 Jan; 20(2):474-8. PubMed ID: 20005709
[TBL] [Abstract][Full Text] [Related]
7. Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors.
Di Fiore A; Pedone C; Antel J; Waldeck H; Witte A; Wurl M; Scozzafava A; Supuran CT; De Simone G
Bioorg Med Chem Lett; 2008 Apr; 18(8):2669-74. PubMed ID: 18359629
[TBL] [Abstract][Full Text] [Related]
8. Carbonic anhydrase inhibitors. Sulfonamide diuretics revisited--old leads for new applications?
Temperini C; Cecchi A; Scozzafava A; Supuran CT
Org Biomol Chem; 2008 Jul; 6(14):2499-506. PubMed ID: 18600270
[TBL] [Abstract][Full Text] [Related]
9. Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies.
De Simone G; Di Fiore A; Menchise V; Pedone C; Antel J; Casini A; Scozzafava A; Wurl M; Supuran CT
Bioorg Med Chem Lett; 2005 May; 15(9):2315-20. PubMed ID: 15837316
[TBL] [Abstract][Full Text] [Related]
10. Carbonic anhydrase inhibitors: the X-ray crystal structure of the adduct of N-hydroxysulfamide with isozyme II explains why this new zinc binding function is effective in the design of potent inhibitors.
Temperini C; Winum JY; Montero JL; Scozzafava A; Supuran CT
Bioorg Med Chem Lett; 2007 May; 17(10):2795-801. PubMed ID: 17346964
[TBL] [Abstract][Full Text] [Related]
11. The first example of a significant active site conformational rearrangement in a carbonic anhydrase-inhibitor adduct: the carbonic anhydrase I-topiramate complex.
Alterio V; Monti SM; Truppo E; Pedone C; Supuran CT; De Simone G
Org Biomol Chem; 2010 Aug; 8(15):3528-33. PubMed ID: 20505865
[TBL] [Abstract][Full Text] [Related]
12. Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the perfluorobenzoyl analogue of methazolamide. Implications for the drug design of fluorinated inhibitors.
Abbate F; Casini A; Scozzafava A; Supuran CT
J Enzyme Inhib Med Chem; 2003 Aug; 18(4):303-8. PubMed ID: 14567544
[TBL] [Abstract][Full Text] [Related]
13. Carbonic anhydrase inhibitors: inhibition of cytosolic carbonic anhydrase isozymes II and VII with simple aromatic sulfonamides and some azo dyes.
Carta F; Pothen B; Maresca A; Tiwari M; Singh V; Supuran CT
Chem Biol Drug Des; 2009 Aug; 74(2):196-202. PubMed ID: 19549076
[TBL] [Abstract][Full Text] [Related]
14. Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with L-histidine as a platform for the design of stronger activators.
Temperini C; Scozzafava A; Puccetti L; Supuran CT
Bioorg Med Chem Lett; 2005 Dec; 15(23):5136-41. PubMed ID: 16214338
[TBL] [Abstract][Full Text] [Related]
15. Carbonic anhydrase activators. Activation of isozymes I, II, IV, VA, VII, and XIV with l- and d-histidine and crystallographic analysis of their adducts with isoform II: engineering proton-transfer processes within the active site of an enzyme.
Temperini C; Scozzafava A; Vullo D; Supuran CT
Chemistry; 2006 Sep; 12(27):7057-66. PubMed ID: 16807956
[TBL] [Abstract][Full Text] [Related]
16. Drug-protein interactions. Refined structures of three sulfonamide drug complexes of human carbonic anhydrase I enzyme.
Chakravarty S; Kannan KK
J Mol Biol; 1994 Oct; 243(2):298-309. PubMed ID: 7932756
[TBL] [Abstract][Full Text] [Related]
17. Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a bis-sulfonamide-two heads are better than one?
Casini A; Abbate F; Scozzafava A; Supuran CT
Bioorg Med Chem Lett; 2003 Aug; 13(16):2759-63. PubMed ID: 12873509
[TBL] [Abstract][Full Text] [Related]
18. Carbonic anhydrase inhibitors: inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides--solution and crystallographic studies.
Alterio V; De Simone G; Monti SM; Scozzafava A; Supuran CT
Bioorg Med Chem Lett; 2007 Aug; 17(15):4201-7. PubMed ID: 17540563
[TBL] [Abstract][Full Text] [Related]
19. Crystallographic studies of inhibitor binding sites in human carbonic anhydrase II: a pentacoordinated binding of the SCN- ion to the zinc at high pH.
Eriksson AE; Kylsten PM; Jones TA; Liljas A
Proteins; 1988; 4(4):283-93. PubMed ID: 3151020
[TBL] [Abstract][Full Text] [Related]
20. QSAR study on carbonic anhydrase inhibitors: aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl moieties, with topical activity as antiglaucoma agents.
Agrawal VK; Bano S; Supuran CT; Khadikar PV
Eur J Med Chem; 2004 Jul; 39(7):593-600. PubMed ID: 15236839
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]